Showing 61 results for Hossein
Samira Shirmohammadi, Saeedehsadat Hosseini, Hassan Amiri,
Volume 10, Issue 2 (2019, Volume 10, Number 2 2019)
Abstract
Background and Aim: Cosmetic surgery is one of the most common phenomena in recent decades. Due to high prevalence of psychiatric disorders among the cosmetic surgery applicants, it is important to explore the pathways and variables which affect mental health of these people. The aim of the present study was to investigate the mediating role of difficulties in excitement adjustment in the relationship between attachment styles and psychopathology in women undergoing cosmetic surgery.
Methods: The present study was descriptive and based on correlation models. The sample included all women who applied for cosmetic surgery who referred to the specialized surgical centers of Kermanshah, 300 of whom were selected by available sampling method. Data were collected by attachment styles. Excitement adjustment difficulty and psychopathology questionnaire and were analyzed by SPSS 22 and LISREL 8/8.
Results: The hypothesized model of research is fitted with the experimental data. There was a significant relationship between attachment styles and psychopathology directly and indirectly. The results of path analysis indicated mediating role of the difficulties of excitement adjustment in the relationship between attachment styles and psychopathology.
Conclusion: Attachment styles and difficulties in excitement adjustment can be effective in preventing, diagnosing and treating of mental disorders, and promoting mental health of cosmetic surgery applicants.
Hamidreza Ahmadi Ashtiani, Alireza Firooz, Hossein Rastegar, Amirhosein Askaripour,
Volume 10, Issue 4 (Volume 10, No4 2020)
Abstract
A wound is described as any laceration in normal anatomic structure and functional integrity of the skin. Chronic wounds don’t progress through the normal wound healing process in 3 months leaving open laceration of different degrees of severity. Diabetic wound healing is an insurmountable process due to the chronic nature of diabetic wounds. For these complications, this has been a challenge in the health care system. By the appearance of regenerative medicine, advisedly stem cell-based therapies and ingredients have been gained the focus of researchers and professionals as well. As there is no definite cure for diabetic wounds and forasmuch as the appearance of regenerative medicine and cell-based therapies there is a big hope to find a definite treatment for diabetic wounds. In this article novel therapies based on stem cells were observed.
Samira Shirmohammadi, Saeedehsadat Hosseini, Hassan Amiri,
Volume 11, Issue 2 (Volume 11, No2 2020)
Abstract
Background and Aim: Cosmetic surgery is one of the most common phenomena in recent decades. Due to high prevalence of psychiatric disorders among cosmetic surgery applicants, it is important to explore the pathways and variables affecting their mental health. The aim of this study was to investigate the mediating role of basic psychological needs in the relationship between attachment styles and psychopathology in women undergoing cosmetic surgery.
Methods: The research was descriptive and based on correlation models. Available sampling method was employed in order to gather data from 300 women referring to Kermanshah specialized surgical centres, for doing cosmetic surgeries. Collected data were analyzed employing attachment styles questionnaire, basic psychological needs and psychopathology, and by SPSS 22 and LISREL 8/8.
Results: The hypothetical model of the research fitted the experimental data. There was a significant relationship between attachment styles and psychopathology directly and indirectly. The results of path analysis indicated a mediating role for the difficulties of psychological needs in the relationship between attachment styles and psychopathology.
Conclusion: Attachment styles and basic psychological needs can be effective in preventing, diagnosing and treating of mental disorders, and promoting mental health of cosmetic surgery applicants.
Seyedezahra Emami Razavi, Fereidoon Memari, Maryam Hosseini, Mohadeseh Azadvari,
Volume 11, Issue 3 (Volume 11, No 3 2020)
Abstract
Post herpetic neuralgia is a chronic neuropathic pain syndrome that it is characterized by pain in the area of the nerve involved distribution after the disappearance of herpes zoster lesions and it may be persistent, refractory and severe. Various treatments including medication, Botox injections, nerve block and physical modalities have been used in the treatment of this syndrome, each has advantages and disadvantages. One of the most widely used methods today is the use of acupuncture. Acupuncture is a low-complication and reproducible treatment that is gaining more and more place in pain management, especially chronic pain. Studies have shown the effect of acupuncture on reducing pain in post-herpetic neuralgia patients. Different parts of acupuncture can be used to reduce pain. The recommended number of sessions is usually 10 to 12 sessions, lasting 20 to 30 minutes. Due to the beneficial effects of acupuncture and its low complication, this method is recommended as one of the treatment methods for postherpetic neuralgia. In this paper, we review the effect of acupuncture on post herpetic neuralgia.
Hamed Hosseini, Rojin Firooz, Alireza Firooz,
Volume 12, Issue 1 (Volume 12, No 1 2021)
Abstract
The fifth paper of reviews on COVID-19 addresses COVID-19 vaccines, as vaccination has started in the world and Iran. In this paper, we review different types of available vaccines and also various platforms for production of COVID-19 vaccines as well as the vaccines produced in each platform in the world and Iran. Then the considerations about vaccination in patients with skin diseases, specially those using immunomodulator drugs will be presented. Finally, the cutaneous adverse effects of COVID-19 vaccines will be reviewed.
Javad Rahmati, Hosseinali Abdolrazaghi, Seyedsaheb Hoseininejad, Hojat Molaei,
Volume 12, Issue 1 (Volume 12, No 1 2021)
Abstract
Introduction: Auricular reconstruction of partial ear defects is usually challenging, especially in extended resections or traumas. Helical rim is the most noticeable part of ear with aesthetic significance, which demands detailed procedures. Helical rim advancement is a known procedure to reshape lacerated rim. In the original technique, a chondrocutaneous flap is raised in order to preserve the posterior skin and consequently, the blood supply.
Case Report: Due to auricle’s rich blood supply, we selected an inferiorly based flap of helical rim, which we incised completely, even the posterior skin, in order to advance the flap more freely to the cephalic side and relaxed cephalically. In five patients with helix tumors, this reconstructive procedure was done without threatening the blood supply and flap ischemia. Moreover, posterior skin traction or subsequent deformity, as one of concerns of reconstructive surgeons, were also eradicated.
Conclusion: It appears that this modification can be noteworthy in auricular reconstruction.
Amir Hosseinalibeygi, Morteza Kashani, Mansour Nassiri Kashani,
Volume 12, Issue 2 (Volume 12, No 2 2021)
Abstract
Sports and the development of nations are very much intertwined. Sports dermatology is a growing discipline. Athletes’ skin diseases are a distinct group of diseases, and that repetitive physical activity combined with environmental stressors puts the athlete at the highest level of risk.The purpose of this study is to equip physicians with basic knowledge of skin diseases in athletes. Lack of knowledge about the role of exercise in the pathogenesis of skin diseases can lead to delayed diagnosis and consequently, incorrect treatment. Skin diseases can be caused directly or indirectly by exercise; there are some skin diseases which exist in a person but appear or intensify with the onset of exercise.
In general, before an athlete should exercise, he should be examined dermatologically to prevent the spread of skin diseases. They should be considered especially for lesions on the less noticeable areas such as the back and inner side of ears. It is better to prepare a map of the patient’s lesions that can be tracked over time, which the possibility of following their changes (Body Mapping).
Athletes should have no general symptoms such as fever for 72 hours before exercising. There should be no secretory skin lesions, otherwise, it is necessary to receive treatments before going to the gym and using the equipment to ensure that the disease does not spread to others.
Ehsan Zarei, Atefeh Gholamhosseini, Narges Ghandi,
Volume 12, Issue 3 (Volume 12, No 3 2021)
Abstract
Background and Aim: Psoriasis is a systemic and non-transmissible chronic inflammatory autoimmune skin disease that about 2-3% of Iranians suffer from it. Cost of management and budgeting and planning for the treatment of patients with psoriasis requires accurate information. The present study estimates the direct and indirect costs for one-year treatment of patients admitted in Razi Dermatology Hospital.
Methods: In this descriptive-analytical study, treatment costs of 170 patients with psoriasis, including direct (medical and non-medical) and indirect costs were evaluated by census method and using a researcher-made checklist, from October 2017 to October 2018. The fee was collected through reviewing patients' bills in the hospital information system and through telephone interviews with patients.
Results: The average cost of one year was 9037480 Tomans ($ 758), of which direct cost of treatment was 90.22% (8178681 Tomans) and indirect cost of treatment was 9.78% (858799 Tomans). The highest cost of treatment was related to pharmaceutical services with 5825233 Tomans. Also, the total direct medical cost was equal to 7069890 Tomans, of which 62% was the insurance share and 38% was the patient share. The findings showed that injecting biological drugs and accommodation had a significant effect on the direct cost of treatment. Supplementary insurance and accommodation variables also affect out-of-pocket costs.
Conclusion: Drugs made up most of the costs. The high price of biologics and the low coverage of these drugs by insurance companies have caused many economic problems for these patients. According to the findings of this study, it seems necessary to review the more complete insurance coverage of these drugs as well as the use of charitable assistance to cover part of the cost for treatment.
Seyedalireza Golshani, Zahra Hosseinhashemi, Mohammadmahdi Zarshenas,
Volume 12, Issue 4 (Volume 12, No 4 2022)
Abstract
Khadab is one of the most important solutions used to beautify and strengthen hair, and Khadab has been used for a long time throughout history. Moreover, putting Khadab has been a long- lasting tradition in the course of history. Also, Iranian medical sources pointed out to the herbs used in Khadab and its role in human health. In this regard, the present study examines Khadab and its place in the history of Islamic civilization.
This is a desk study which is conducted through reviewing the main sources, Hadiths, and written sources of Iranian medicine. Also, various databases such as Magiran, SID, Google Scholar were searched to reach new findings. What is important in this study is putting Khadab during the course of history for adornment and human health. Moreover, diseases were cured through putting Khadab.
Putting Khadab and promoting this act can be effective in improving mental and physical health. Therefore, putting Khadab and its effect on the health of the human body and the herbs used in it need further investigation, as this research can be used to enhance the knowledge of the experts of traditional medicine.
Elahe Nazari, Kambiz Kamyab Hesari, Sahar Montazeri, Nazanin Mansourzadeh, Vida Feizi, Hossein Mortazavi, Alireza Ghanadan, Nafiseh Esmaeli,
Volume 13, Issue 1 (Volume 13, No 1 2022)
Abstract
Background and Aim: Direct immunofluorescence (DIF) is represented as a gold standard method in diagnosis of autoimmune blistering dermatoses. Normal saline, liquid nitrogen and michel’ solution are a widely accepted media for preserving biopsy samples of skin or mucosa before DIF examination. Occasionally clinicians put the biopsy specimen taken for DIF in formalin 10%, occasionally clinicians ordered DIF retrogradely and only a paraffin-embedded biopsy specimen exposed to formalin 10% is available. To determine the diagnostic value of DIF when it was performed on biopsy samples of skin or mucosa exposed to formalin 10% in comparison to the same biopsy samples exposed to normal saline.
Methods: In 74 patients (38 immunobullous and 23 chronic dermatitis), which the latter served as the normal controls, 2 perilesional punch biopsy of skin or mucosa were done, one put in formalin 10% and fixed in paraffin and one put in normal saline, and DIF was done on both samples.
Results: DIF sensitivity and specificity was with IgG 31.5% and 100% in pemphigus and 15.36% and 93.44% in BP, with C3 39.47% and 100% in pemphigus and 7.69% and 91.80% in BP, respectively.
Conclusion: DIF on specimens exposed to formalin 10% in comparison to specimens exposed to normal saline is less sensitive but approximately as specific as it is in the diagnosis of pemphigus and BP patients and especially can be useful in pemphigus patients when only a formalin exposed samples is available.
Javad Rahmati, Shahriar Haddady Abianeh, Hosseinali Abdolrazaghi, Hojjat Molaei,
Volume 13, Issue 3 (Volume 13, No 3 2022)
Abstract
Background: Skin lesions and need for tissue evaluation, makes skin surgery an important part of treatment. Each excision is accompanied by skin repair. One of side effects of lesion excision is dog ear and cosmetic problems, particulary on face.
Case Report: A middle age woman presented with an old leishmaniosis scar in her face. she asked how can we remove the lesion with minimal scar. In the planned operation the lesion was excised some deeper fatty tissues at both ends. At the end of wound closure, there was not ant dog ear around wound.
Conclusion: There are numerous options to prevent and correct dog ears at the end of skin closure- depending on size and location of the lesion. in our recommended technique, subdermal fatty excision attached to the lesion, may remain minimal extra skin at the end of skin closure.
Amirhoushang Ehsani, Pedram Nourmohammadpour, Kambiz Kamyab Hesari, Seyedmohammad Bahrainian, Mina Koohian Mohammadabadi, Ala Ehsani, Amirhossein Rahimnia,
Volume 13, Issue 4 (Volume 13, No 4 2023)
Abstract
Background and Aim: One of the most important pathologies of tattooing is granulomatous reaction to the tattoo which is usually represented by symptoms like pain, inflation, redness and tenderness at the tattoo area. Granulomatous reaction to tattoo occurs at all ages and has been seen among both male and female. Due to the new rise in popularity of cosmetic tattoos and its pathologies, we intend to explore a descriptive study of the demographic and histopathologic characteristics of the granulomatous reactions due to cosmetic tattoos.
Methods: Razi hospital patients with proven tattoo granuloma pathology in a 3-year period were identified and studied and their demographic-histological characteristics were recorded. The study is of a cross-sectional type. 196 patients were enrolled in the study, a questionnaire was prepared for each patient and information was collected through them.
Results: The mean ± standard deviation age of the patients was 45.46±8.54. The mean ± standard deviation tattoo time was 4.18±4.33. The mean ± standard deviation frequency of tattooing was 1.64±1.8. The most common tattoo area was eyebrow in 88.3% of the patients and least common was upper eyelid in 0.6%. The most common pathology result was tattoo granuloma in 41.7% of the patients and the least common was Lichenoid in 2.8%.
Conclusion: Considering the highest frequency of pathological diagnosis of tattoo-granuloma (Sarcoidal and foreign body) with 41.7% in our study and observing the relationship between tattoo-granuloma and sarcoidosis in previous studies, complete examination of patients, long-term follow-up of patients which will have sarcoidosis in the future and examining the clinical response to treatment seems logical and beneficial. It is also important to consider whether the treatment of current lesions will play a role in preventing sarcoidosis in the future or not.
Amirhoushang Ehsani, Hasan Hajmohammadtaghiseyrafi, Pedram Nourmohammadpour, Mahdi Naghdipour, Mina Koohian Mohammadabadi, Ala Ehsani, Amirhossein Rahimnia,
Volume 14, Issue 1 (Volume 14, No 1 2023)
Abstract
Background and Aim: Lower limb telangiectasias are commonly seen in the general population and especially in females. This disorder not only causes cosmetic problems but also can cause pain and related problems of increased venous blood pressure. These varicose veins are one of the most common causes that patients refer to dermatology clinics. Considering some complications and limitations of sclerotherapy, we decided to investigate the efficacy and safety of the Long-Pulsed Nd:YAG 1064-nm laser as an alternative method.
Methods: 29 patients underwent at least three sessions of 1064 nm Nd: YAG laser treatment at intervals of 4 weeks. Before the first treatment session, after each session, and six months after the last session, photos were taken of the treatment site. Finally, clinical response and satisfaction rate with the treatment were recorded based on the score of a secondary dermatologist and the patient himself based on the improvement criteria from 0 to 4.
Results: According to the dermatologist's judgment, the average satisfaction with the treatment is 3.38 out of 4 with a standard deviation of 0.5, and based on the patient's assessment, it is 3.2 out of 4 with a standard deviation of 0.71, which is equivalent to more than 76% of the effectiveness of Nd:YAG 1064 nm laser in the treatment of telangiectatic veins. The pain during laser treatment was recorded as 6.27 with a standard deviation of 2.64 based on The VAS Scale.
Conclusion: Our experience has demonstrated that the long-pulsed 1064 nm Nd:YAG laser is an effective, reliable, safe method in the treatment of telangiectatic and reticular veins of the lower limbs with minimal side effects and complications.
Mahbobeh Dehghan Nayeri, Mohammadhossein Bayazi,
Volume 14, Issue 1 (Volume 14, No 1 2023)
Abstract
Background and Aim: The purpose of this research was to compare the effectiveness of cognitive behavioral and emotion-focused group therapy on reducing the symptoms of psoriasis, psychological distress and perception of body image.
Methods: This was a semi-experimental research of pretest posttest type with a control group. The statistical population of this research included all patients who were diagnosed with psoriasis in spring of 2022 by referring to dermatologists in Mashhad. 45 psoriasis patients were selected by available sampling method and replaced randomly in two experimental groups (CBT and EFT) and control group (each groups 15). The experimental groups was treated for 8 sessions, one session of 90 minutes per week. The control group received no intervention. Parents completed the Psychological Distress Scale, Body Image Concern Inventory and the Physical Symptoms Questionnaire with Psoriasis Area Severity Index before and after the treatment sessions. The data were analyzed by Analysis of covariance.
Results: The findings showed that cognitive-behavioral and emotion-focused reduced psychological distress (P<0.01, F=21.06), improved perception of body image (P<0.01, F=33.65) and reducing the severity of psoriasis symptoms (P>0.01, F=12.67) are effective. Also, cognitive behavioral therapy is more effective method to reduce psychological distress and improve perception of body image (P<0.01). However, there is no significant difference between the effectiveness of cognitive-behavioral therapy and emotion-focused therapy in reducing psoriasis symptoms of patients (P<0.05).
Conclusion: Both therapies can play a key and effective role in controlling the symptoms of psoriasis.
Javad Rahmati, Hosseinali Abdolrazaghi, Shahriar Haddady Abianeh, Hojjat Molaei,
Volume 14, Issue 2 (Volume 14, No 2 2023)
Abstract
Introduction: Skin lesions and masses of forehead are challenging topics in the field of reconstruction. Skin grafts and local flaps have significant role in reconstruction of skin defects of forehead. Proper design of flap can save hairline configuration and symmetry of eyebrows.
Case report: A young woman with congenital sebaceous nevus-Jadassohn-wanted to remove this lesion. After excision, there was skin defect of 4 cm diameter. A O to T flap designed and incisions were on bilateral hairline. The defect was covered without any disruption of hairline.
Conclusion: Rotational-advancement flaps are among reliable flaps in reconstruction of forehead skin defects. O to T flap belongs to this category which is effective in traumatic patients and reconstruction following tumor resections.
Seyedhossein Jahanbakhsh, Arghavan Azizpoor, Maryam Nasimi, Amirhoushang Ehsani, Pedram Noormahamadpoor,
Volume 14, Issue 3 (Volume 14, No 3 2023)
Abstract
Background and Aim: The present study aims to assess the prevalence of obstructive sleep apnea in patients with psoriasis referring to Razi Hospital.
Methods: Participants were assessed for demographic characteristics, Psoriasis Area and Severity Index (PASI), disease duration, place of residence, education level, and were also evaluated using the Stop-Bang and Berlin questionnaires to assess the risk of obstructive sleep apnea. The high and low-risk groups for obstructive sleep apnea were compared regarding these parameters.
Results: Based on the Stop-Bang criteria, 43 individuals (41.3%) had moderate risk, and 23 individuals (22.1%) had high risk of obstructive sleep apnea. According to the Berlin questionnaire, 48 individuals (46.2%) were at high risk for obstructive sleep apnea. The mean age of individuals with high risk of obstructive sleep apnea according to the STOP-BANG criteria was significantly higher than those with moderate risk (mean=58.3, standard deviation=10.6, compared to mean=48.1, standard deviation=16.1, P = 0.039) and low risk (mean=41.7, standard deviation=17.8, P< 0.001). Additionally, BMI differed significantly among the three groups based on the Stop-BANG criteria, with higher BMI observed in individuals at higher risk for obstructive sleep apnea (P<0.05). BMI was significantly higher in individuals with high risk of obstructive sleep apnea according to the Berlin criteria compared to those with low risk (mean 31.1 versus mean 26, P<0.001).
Conclusion: The findings of this study highlight obstructive sleep apnea as a comorbidity associated with psoriasis.
Hossein Sharifi, Ensieh Lotfali,
Volume 14, Issue 3 (Volume 14, No 3 2023)
Abstract
Background and Aim: Considering the increase of dermatophytosis trough the Iran and world as well, especially ringworm of the body and groin due to terbinafine-resistant species and the high speed of disease transmission, in order to choose the appropriate treatment, considering the time required for the treatment of the disease and early detection of resistant cases treatment is required. The present study was conducted to determine the antifungal sensitivity of Trichophyton rubrum, Microsporum canis and Epidermophyton flucosum strains to common antifungal drugs.
Methods: Antifungal sensitivity test (broth microdilution) was performed for 20 specimens obtained from patients according to CLSI (Clinical and Laboratory Standard Institute) M38-3rd ED protocol, for terbinafine, itraconazole and voriconazole.
Results: According to the antifungal susceptibility test results, 5 patients were resistant to terbinafine and showed a minimum inhibitory concentration more than 2, 3 patients were tolerant to terbinafine and showed a minimum inhibitory concentration between 0.5 and 1. Based on the results of the antifungal susceptibility test, 7 patients were tolerant to itraconazole and showed the minimum inhibitory concentration between 0.5 and 1. All isolates responded well to voriconazole.
Conclusion: The results of the antifungal sensitivity test highlight the importance of mycological tests on dermatophytic skin lesions to prevent the spread of drug-resistant species.
Samira Shahhosseini, Moazameh Kordjazi, Saman Ahmadnasrollahi, Seyedmahdi Ojagh, Atefe Naeimifar, Salim Sharifian,
Volume 15, Issue 1 (Volume 15, No 1 2024)
Abstract
Background and Aim: Marine seaweeds are a valuable source of bioactive ingeredients with the possibility of different effects in cosmeceutical industries such as skin health products. One of the main characteristics of the skin is moisture which plays an important role in maintaining metabolism, enzymatic activity, mechanical properties, appearance and protective barrier. The objective of the present study was to formulate the water extract of brown algae Sargassum tenerrimum with antioxidant and antibacterial properties as a moisturizing cream to evaluate physicochemical stability and microbial growth.
Methods: Algae were collected from the Persian Gulf intertidal zone and was washed with seawater, then transferd to Seafood Processing Laboratory in Gorgan University of Agricultural Sciences and Natural Resources for extraction process, after that formulation of 1% moisturizing cream was made at Center for Research and Training in Skin Diseases and LeprosyTehran University of Medical Scinces. Statistical analysis of antibacterial properties of water extract was performed by SPSS software version 22 and one way ANONA was used to analyse the data. The comparison between the means were investigated by Duncan’s test used for measuring significant differences at 5 percent level. Finally, the charts were created by using Excel software. The results of the study were reported as mean ± standard deviation.
Results: According to the results, the prepared 1% cream was completely stable and homogeneous in room temperature and oven for 6 months and successfully passed microbial tests.
Conclusion: In view of the above mentioned, the manufactured cream efficacy was well done and can be introduce as a skin moisturizing agent.
Mahdieh Ghiasi, Seyedkhalil Pestehei, Seyedamirhossein Javadi, Seyediman Seyhoun,
Volume 15, Issue 1 (Volume 15, No 1 2024)
Abstract
The skin, as the outer layer, protects the body against external factors. Wounds can negatively affect its performance. Wound healing includes three stages of inflammation, proliferation, and regeneration, which begin immediately after injury. Also, some factors such as infection, obesity and diabetes can disrupt the natural healing process that leads to chronic wounds. Various surgical and non-surgical treatments have been used to manage chronic wounds, including hyperbaric oxygen therapy, ultrasound therapy, laser therapy, and skin grafting. These treatments have advantages and disadvantages. Recently, stem cells have been used as a surgical treatment for chronic wound healing. Stem cells are highly proliferative cells that can maintain their ability to divide and regenerate for a long time. Among the different types of stem cells, MSCs have many advantages such as ease of harvest, availability, and multilineage differentiation capacity for cell therapy. In addition, they showed some properties that could be useful in the clinical application of ASCs, including angiogenesis, immune system modulation, and improved tissue regeneration. This study was conducted by collecting data from reliable scientific sources from April 1401 to January 1402 at the Research Institute of Neurosciences, Brain and Spinal Cord Injury Research Center of Tehran University of Medical Sciences. Several studies have shown that ASCs can be a suitable candidate for wound healing due to their special characteristics. The purpose of this review is to discuss the use of ASCs in wound repair and healing as a new strategy in the treatment of skin problems.
Ala Ehsani, Amirhoushang Ehsani, Zahra Razavi, Mina Koohian Mohammadabadi, Mahshidsadat Ansari, Zeynab Aryanian, Pedram Nourmohammadpour, Amirmohammad Almasi, Amirhossein Rahimnia,
Volume 15, Issue 2 (Volume 15, No 2 2024)
Abstract
Background and aim: As the use of botulinum toxin to treat glabellar lines increases, particularly in Iran, where foreign products (e.g. Dysport) are relatively expensive, it becomes important to compare the efficacy, side effects, and duration of action of two locally produced botulinum toxin brands, Masport® and Dyston®. This study seeks to assess and compare the treatment results of these two medications.
Methods: In this cross-sectional, descriptive, retrospective study, the medical records of 81 patients who visited Razi Dermatology Hospital for the treatment of moderate to severe glabellar lines were reviewed. Data related to patient satisfaction, duration of action, and side effects of Masport® and Dyston® botulinum toxin were collected and analyzed via a questionnaire.
Results: The mean satisfaction score was 7 for the Dyston® group and 7.7 for the Masport® group, with no statistically significant difference between the two groups (P=0.142). Additionally, the mean duration of action was 3.5 months for Dyston® and 3.8 months for Masport®, with no significant difference observed. Headache was the most common side effect reported, with no other major adverse events noted. Furthermore, there was no statistically significant difference in the incidence of side effects between the two groups.
Conclusion: The findings of this study indicate that both Dyston® and Masport® have similar efficacy and safety profiles. The choice between them can be primarily based on cost and patient or physician preference rather than any significant therapeutic differences. Larger studies are recommended to further validate these findings.
