Leila Khaki, Gholamhasan Vaezi, Azin Ayatollahi, Alireza Firooz,
Volume 11, Issue 3 (10-2020)
Abstract
The aim of this study was to investigate the possibility of using saliva instead of serum (as a simpler method without the need for blood sampling) to determine the level of some cytokines and enzymes. In this study, the levels of cytokines IL10, IFN-Y, TNF-α, TGF-β and the antioxidant enzymes glutathione reductase and glutathione peroxidase were measured in the saliva and serum of three patients with alopecia totalis by ELISA. Comparison of the levels of these substances in saliva samples at 5 am, saliva at 11 am and serum at 11 am with Friedman test did not show a significant difference. Therefore, saliva samples may be a good alternative to serum in the study of immunological factors.
Sharareh Rezaeian, Hamidreza Pourianfar,
Volume 13, Issue 4 (2-2023)
Abstract
Reishi mushroom (Ganoderma lucidum) is a unique medicinal mushroom that has been used for the treatment of various diseases in Asian countries for more than 4 thousand years. Today, this mushroom is also used in treatments related to traditional medicine. In addition to its diverse biological properties, its positive effects in improving the quality of the skin and treating skin diseases have attracted the attention of researchers. Polysaccharides and triterpenes are among the most important and effective metabolites of this mushroom, which are important in skin treatment and health due to their antioxidant and anti-inflammatory functions. This review summarizes the latest research achievements on the role of this mushroom in skin health and treatment. A number of studies have shown that the extracts of Reishi mushroom can accelerate wound healing, relieve post-burn infections, and prevent skin flaps due to ischemia (re-perfusion) damage. The effect of Reishi mushroom extracts on the prevention and treatment of wrinkles and the effect on skin whitening has made them a natural ingredient for skin care. Also, studies conducted on the effects of Reishi mushroom in the treatment of some skin diseases such as atopic dermatitis (eczema), cutaneous sarcoidosis, and the potential use of this mushroom in the treatment of skin cancer have been discussed.
