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Showing 4 results for Cicatricial Alopecia
Demographic evaluation of neutrophilic scarring alopecia in Razi Hospital in Tehran in 2005-2009
Amir Hooshang Ehsani, Mahboobeh Sadat Hosseyni, Kambiz Kamyab, Masoomeh Rohani Nasab, Amir Reza Hanifnia, Pejman Mobasher, ,
Volume 3, Issue 2 (6-2012)
Abstract

Background and Aim: Cicatricial alopecia is characterized by permanent destruction of the pilosebaceous unit, leading to irreversible hair loss, and has primary and secondary types. Primary type, based on predominant inflammatory infiltration in histology, is divided to neutrophilic, lymphocytic and mix types. Decalvans folliculitis, dissecting cellulitis and acne keloidalis are 3 subtypes of neutrophilic group. In this study frequency of each subtype and the distribution of age, gender and duration of disease have been reviewed.

Methods: This retrospective study was performed on patients with clinical diagnosis of cicatricial alopecia and histologic confirmation referred to Razi hospital in Tehran in 2005-2009.

Results: Of 135 patients with mean (mean±SD) age of 32±10.6 years, 71.9% were male and 28.1% were female. The diagnoses included decalvans folliulitis (72.6%) with mean age of 31.89 years, dissecting cellulitis (25.0%) with mean age of 32.4 years and acne keloidalis (1.5%) with mean age of 52 years. The mean duration of disease was 4.2±3.9 years (4.08 years in male and 4.7 years in female). The mean duration of disease in decalvans folliulitis was 4.7, in dissecting cellulitis was 1.9 and in acne keloidalis was 17.5 years.

Conclusion: Neutrophilic scarring alopecia is more common in men and in the third decade of age and the most common type is decalvans folliulitis.


Demographic, clinical and histopathological characteristics in different kinds of cicatricial alopecias
Hamidreza Ghasemi Basir, Mahmood Farshchian, Pedram Alirezaei, Mahdis Jahani,
Volume 5, Issue 4 (1-2015)
Abstract

Background and Aim: Cicatricial alopecia is the result of irreversible substitution of hair follicles with fibrotic tissue and presents as permanent loss of hair. Only a few studies have investigated the clinical and histopathological characteristics of cicatricial alopecia in Iran. The aim of this study was to determine the demographic, clinical and histopathological characteristics of patients with cicatricial alopecia who referred to our dermatology outpatient clinic in Farshchian hospital in a two year period, and to evaluate the diagnostic value of histopathologic criteria in diagnosing different kinds of cicatricial alopecias.

Methods: This was a cross-sectional study. Eighty nine patients who underwent skin biopsy due to clinical diagnosis of cicatricial alopecia were included. Demographic and clinical characteristics of patients as well as clinical diagnosis were recorded and the biopsy samples were evaluated by two different pathologists who were unaware of each other's diagnosis. Histopathological diagnosis of patients according to each pathologist's opinion was recorded separately and statistical analysis was performed to obtain the coincidence coefficient between two pathological diagnosis.

Results: The most common forms of cicatricial alopecias due to clinical and histopathological diagnosis were: lichen planopilaris, disciod lupus erythematosus, alopecia areata, pseudopelade of Brocq, folliculitis decalvans and central centrifugal cicatricial alopecia. Moreover, our findings showed a powerful coincidence coefficient between clinical diagnosis and the first pathologist diagnosis (kappa=0.836), an average to powerful coincidence coefficient between the second pathologist diagnosis and clinical diagnosis
(kappa=0.703) and finally an average to powerful coincidence coefficient between the two pathologists diagnosis
(kappa=0.663).

Conclusion: Diagnosis of cicatricial alopecia depends upon clinical and also histopathological examination. Diagnostic value of histopathological criteria even at the end of scarring process when there is considerable overlap between microscopic findings of different etiologies of cicatricial alopecias is still acceptable and there is no need to re-evaluate the biopsy specimen by a second pathologist in order to confirm the diagnosis.

Primary cicatricial alopecia in patients admitted to a referral dermatology clinic in Hamadan, between 2002 and 2012: A clinico-pathologic study
Ameneh Yazdanfar, Leila Khezrian, Leila Mousavi, Mahtab Feiziyan,
Volume 6, Issue 3 (10-2015)
Abstract

Background and Aim: Cicatricial alopecia refers to lesions that result in permanent and irreversible hair loss and are associated with destruction of hair follicles. In this alopecias the hair follicle is replaced with connective tissue. After remission of initial infection or inflammation, hair regrowth is unlikely.

Methods: In this retrospective cross-sectional study, 222 patients with cicatricial alopecia, admitted to Farshchian Hospital, Hamadan, Iran were investigated. Hospital records of patients with cicatricial alopecia were reviewed, and their demographic as well as clinical data were extracted and entered into prepared data gathering forms.

Results: One-hundred and ten patients (49.5%) had discoid lupus erythematosus, 71 patients (31.9%) had lichen planopilaris, 23 patients (10.4%) had pseudopelade of Brocq, 11 patients (4.9%) had keratosis pilaris spinulosa decalvans and 3 patients (1.3%) had central centrifugal cicatricial alopecia. Each of alopecia mucinosa and dissecting cellulitis/folliculitis were observed in 2 patients (0.9%). The correlation between of illness, extent of disease, gender, location, occupation, and clinical features of the disease were studied.

Conclusion: Cicatricial alopecia usually results in irreversible hair loss, but early diagnosis and treatment can prevent the progression of the lesions and its complications. The diagnosis of this disease is possible with a clinicopathologic study.


Evaluation of clinical-pathologic causes of scarring alopesia in patients referred to dermatology clinic of Imam Reza Hospital in Ardebil during the year of 2018
Fatemeh Alizadeh Chaychian, Maryam Kazemi, Majid Rostami Moghaddam,
Volume 11, Issue 3 (10-2020)
Abstract

Background and Aim: Cicatricial (scarring) alopecia is a group of disorders in which permanent hair loss results from replacement of hair follicles by fibrosis or hyalinized collagen, which includes two types: primary such as discoid lupus erythematosus (DLE), lichen plano pilaris (LPP), frontal fibrosing alopecia (FFA), Folliculitis decalvans, and secondary like kerion and burn. The aim of this study was to evaluate the frequency of different types of scarring alopecia in patients referred to Imam Reza Dermatology Clinic in Ardebil in 1397.

Methods: In this descriptive cross-sectional study, 96 patients referred to the dermatology clinic of Imam Reza Hospital, Ardebil, Iran, were evaluated. Epidemiologic and pathologic causes of primary and secondary cicatricial alopecia were analyzed using descriptive statistics in SPSS version 16 software.

Results: The most common causes among patients with primary cicatricial alopecia were DLE (51.16%), LPP (6.25%), acne keloidalis (4.16%), folliculitis decalvans (2.08%), FFA (2.08%) and pseudopelade of Brocq 1.04%). In patients with secondary cicatricial alopecia the most common causes were kerion (55.2%), followed by morphea cutaneous lymphoma and burn (1.04%).

Conclusion: Considering that the majority of patients in rural area had kerion (92.45%), we can prevent the spread of the disease by improving hygiene standards as an important factor in controlling this disease in order to early diagnosis and treatment.


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