Hossein Kavoussi, Mansour Rezaei, Danyal Isapour, Seyyed Reza Seyyed Mohammad Doulabi,
Volume 3, Issue 2 (6-2012)
Abstract
Background and Aim: Basal cell carcinoma (BCC) is the most common type of malignancy that rarely causes death but results in cosmetic problems and is associated with high treatment cost. Clinical characteristics of this cancer are related to the host and environmental factors. Theses factors are specific for each area and may change over the time. The aim of this study was to find clinical characteristics of BCC in Kermanshah city.
Methods: This cross-sectional study was done on 119 histopathologically documented BCC cases in Haj Dayi skin clinic in Kermanshah in 2009. Demographic data of patients and characteristics of the lesions including their number, location, size and clinical type were recorded. Data were analyzed using ANOVA and chi squared tests.
Results: The patients had a total number of 171 BCC lesions. Nodular type encompassed 158 (92.4%) lesions and was the most common clinical form. Pigmented subtype included one third of lesions and was significantly more common in male patients with moderate brown skin and following radiotherapy (P<0.05). The nose was the most common area of involvement and actinic keratosis was the most common associated skin lesion.
Conclusion: In this study, the most common clinical and pathological type of BCC was nodular type. It was observed in old patients, those with outdoor jobs and was associated with actinic keratosis. Educational and screening programs for prevention, early detection and diagnosis, and appropriate treatment for high-risk individuals are suggested.
Ala Ehsani, Bahar Sadeghi, Amirhoushang Ehsani, Mahshid-Ol- Sadat Ansari, Zahra Razavi, Mina Koohian Mohammadabadi, Kambiz Kamyab, Pedram Nourmohammadpour, Mobina Kamalabadi Farahani, Amirhossein Rahimnia,
Volume 15, Issue 3 (11-2024)
Abstract
Background and Aim: Angiokeratomas are rare vascular lesions, typically presenting as small red to purple macules or papules on the skin. These lesions are usually benign, though they can undergo changes in thickness and color over time. Certain types of angiokeratomas may also signal underlying metabolic disorders, necessitating careful clinical attention. This study aims to analyze the clinical and demographic features of angiokeratoma in Iranian patients at Razi Dermatology Hospital.
Methods: This descriptive, retrospective cross-sectional study examined 199 patients diagnosed with angiokeratoma between 2013 and 2023. Data on demographics, lesion characteristics (location and size), family history, and treatment methods were collected from medical records and analyzed using SPSS. Both parametric and non-parametric statistical tests were applied to assess associations, with a significance level set at 0.05.
Results: The mean age of patients was 24.75 years, with the second and third decades showing the highest prevalence. Among the patients, 51.3% were male and 48.7% female. Lesions most commonly appeared on the lower extremities (40.7%) and genital area (18.6%). Treatment methods included cryotherapy (68.14%), laser (27.14%), and electrodessication (4.44%), with cryotherapy proving the most effective among them.
Conclusion: This study provides valuable insights into the prevalence, clinical characteristics, and preferred treatment approaches for angiokeratoma in Iranian patients. Broader studies across various centers, along with long-term follow-up, are recommended to further investigate the clinical course, therapeutic outcomes, and potential complications associated with different treatment methods.
