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Comparison of pediatric-onset psoriasis with adult-onset psoriasis
Zahra Hallaji, Maryam Akhyani, Vahide Lajevardi, Mayade Raeiati Damavandi,
Volume 3, Issue 3 (9-2012)
Abstract
Background and Aim: Psoriasis is a chronic papulosquamous disorder, which affects about 2% of the population. Psoriasis is relatively common in childhood: more than 10% of cases start before the age of 10. Tha aim of this study was to compare the clinical characteristics between pediatric-onset and adult-onset psoriasis in Iranian patients. 
Methods: In 2006 and 2007, clinical data were collected from all patients with psoriasis diagnosis referred to Razi Hospital. They were categorized into two groups: pediatric-onset psoriasis patients and adult-onset psoriasis patients. Clinical variables such as number of patients, gender, age of onset, family history, and stress as a precipitating factor, the first site of involvement, clinical type and involved sites were compared between the two group.
Results: From total of 162 patients, 50 patients (33.2%) were considered as pediatric-onset group. The percentage of males in the pediatric-onset group was 48% compared with 58.9% in the adult-onset group. In the pediatric-onset group positive family history was 20% and in the adult-onset group was 12.5%. Stress as a precipitating factor was nearly the same in both groups. Plaque type psoriasis was the most common clinical presentation and the head and neck was the most common site of involvement in both groups.
Conclusion: Our findings, similar to previous studies showed that the involvement of female gender, family history and the onset of psoriasis on the scalp in children were more than adults.

Epidemiological study of surgically treated patients with cutaneous melanoma in southern Iran: a 5-year retrospective analysis
Maryamsadat Sadati, Arefe Ferdowsi, Majid Akrami, Armin Gorjian, Mojgan Akbarzadeh Jahromi, Yasamin Dehghan,
Volume 16, Issue 2 (7-2025)
Abstract

Background and aim: Cutaneous melanoma is one of the most aggressive skin cancers with high metastatic potential and considerable mortality. Prognostic factors such as tumor thickness, surgical margin status, and lymph node involvement play a decisive role in prognosis and treatment selection. Reports from Iran also indicate an increasing incidence of this disease, and providing epidemiological and clinical data at the regional level can help guide therapeutic policies.
 

Methods: In this retrospective cross-sectional study, all patients with cutaneous melanoma who underwent surgery at Shahid Faghihi Hospital, Shiraz, between 2019 and 2023 were evaluated. Demographic information, lesion site, tumor size and thickness, histopathological type, surgical method, margin status, and the need for reoperation were extracted from medical records and analyzed using descriptive and analytical statistical tests.
 

Results: A total of 84 patients were included (51.2% male and 48.8% female). The most common histopathological type was malignant melanoma (31%). Lesions were most frequently located on the hands (28.6%) and feet (21.4%). The majority of lesions measured between 2–5 cm (36.9%). Only 2.4% of patients had tumors thinner than 1 mm, while 11.9% had tumors thicker than 5 mm. Excision was the most common surgical method (54.8%). Surgical margins were free of tumor in 53.6% of cases, and 61.9% of patients required reoperation.
 

Conclusion: The findings indicate that cutaneous melanoma in southern Iran predominantly occurs in the extremities, and the high rate of reoperation underscores the need for more precise surgical planning and earlier diagnosis.


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