Showing 6 results for Cutaneous Reaction
Bahareh Malekafzali, Franak Najibi,
Volume 2, Issue 1 (3-2011)
Abstract
Background and Aim: Cutaneous drug reaction is a common side effect of antiepileptic drugs and a frequent cause of treatment discontinuation. These reactions ranges can be a mild maculopapular rash to Stevens-Johnson Syndrom and toxic epidermal necrolysis. Among the traditional anticonvulsant drugs the aromatic compounds Phenytoin, Phenobarbital and Carbamazepin have been associated with relatively higher incidences of cutaneous reactions which can hospitalized the patient. Some of the newer drugs also can induce this problem, especially lamotrigine.
Methods: All records of patiens who were hospitalized at hospitals related to Islamic Azad as well as Rasol Akram hospital with a diagnosis of cutaneous drug reaction to anticonvulsant therapy in 8 years period were reviewed.
Results: The most common culprit was phenytoin (32%) and the least common drug was lamotrigin (3%).
Conclusion: Cutaneous reaction to anticonvulsant drugs is common and sometimes may be life threatening which needs serious treatment options.
Esmaeil Alizadeh, Abbas Aghaei Afshar, Mohammadamin Gorouhi, Faeghe Shiri,
Volume 11, Issue 4 (1-2021)
Abstract
Introduction: Fleas are small, blood-sucking insects that can transmit some pathogens to human and animals.
Case Report: This paper presents a 21-year-old woman with severe skin reactions in her right forearm. After initial examinations, the symptoms were recognized as skin reaction caused by the bite of some human blood-sucking insects. Finally, after 15 days of flea bites, the symptoms were treated with topical after bite cream and oral antihistamines. In order to prevent and control the infestation of this blood-sucking pest, public awareness should be increased specially in at risk populations.
Conclusion: Increasing awareness among physicians, about the symptoms of this health pest can help to accelerate treatment process.
Hamideh Herizchighadim,
Volume 13, Issue 1 (5-2022)
Abstract
COVID-19 pandemic has led to many mortalities since the beginning of 2020. As there was no previous experience, no specific therapy was used, except for gloves, masks, special clothes, and antiseptics. So various pharmacologic and
non-pharmacological treatments were tried. World Health Organization published therapeutic protocols in the first weeks of the pandemic that has been changed over months. As there are constant and variable signs and symptoms in different patients in different countries, therapeutic modalities and drugs are various too. Some of these drugs have been used for viral and nonviral diseases, including Tamiflu (that has been used in the treatment of influenza), Ribavirin (an effective drug in hepatitis C infection), immunoglobulin (that has been used in the treatment of various disorders like Stevens-Johnson syndrome), hydroxychloroquine (for the treatment of systemic lupus erythematosus and other rheumatologic disorders), azithromycin (that is used for upper respiratory tract infections, acne, etc.). On the other hand, consuming spices such as ginger and turmeric, vitamins like vitamin C and vitamin D, and zinc supplements have been suggested. Over months, treatment complications, including side effects of drugs and protective equipment appeared. Complications included a broad spectrum of pruritus and nonspecific rash to Stevens-Johnson syndrome and angioedema. Aggravation and recurrence of dermatitis due to the use of protective equipment and antiseptics have been observed. Increasing knowledge about treatment complications will result in early diagnosis and management and obviously decreasing mortality rates and costs.
This article is a review of common cutaneous side effects of therapeutic modalities and preventive methods in COVID-19.
Esmaeil Alizadeh, Mohammadamin Gorouhi, Leila Shirani Bidabadi, Abbas Aghaei Afshar, Mohadese Ordouni, Faezeh Rohani, Hanane Maleki Azaraki, Yasaman Shafiee,
Volume 13, Issue 4 (2-2023)
Abstract
Background: Tarantulas (Camel spiders) are order that belong to classes of arachnida and phylum of arthropoda. They can make a painful bite in human.
Case Report: This paper presents 34 and 40-year-old men with skin reactions in their left legs. After initial examinations, the symptoms were recognized as skin reaction caused by the bite of some nuisance insects. After one day, a lesion including 2 red dots appeared on the patient's leg. After a few hours, skin lesions were observed in both patient, and by washing with soap and water after 7 days, the symptoms completely disappeared and the bite improved.
Conclusion: Increasing awareness among physicians, about the symptoms of this nuisance insects can help to accelerate treatment process.
Mohsen Mohebbi Nodez, Abolfazl Ataei, Ismaeil Alizadeh,
Volume 15, Issue 1 (5-2024)
Abstract
Background and Aim: Spiders are one of the largest orders of arachnids, found worldwide on all continents except Antarctica. Many species of spiders live in close proximity to humans and generally inject poison into other animals, including humans, to protect themselves or to hunt.
Case Report: In this paper, a seven-year-old boy is presented who came to the hospital complaining of skin reactions in the eye, knee, and lower leg area. Skin lesions appeared on the boy's body after a few hours. After 24 hours, the skin lesions intensified, and inflammation and redness along with itching occurred on the boy's body. Finally, after 5 days, the skin lesions disappeared completely by washing with soap and water along with the use of Calamine lotion and the bite site improved.
Conclusion: Increasing awareness among physicians, about the symptoms of this nuisance insects can help to accelerate treatment process.
Seyedmohsen Mohebi Nodez, Alireza Zare Karizi, Bita Ghaderi, Shahrazad Aghababaei, Ismaeil Alizadeh,
Volume 15, Issue 3 (11-2024)
Abstract
Background: Scorpions are known as one of the oldest venomous animals on the planet. Scorpion bites are an important public health problem in many parts of the world, including Iran.
Case Report: In this paper, a 49-year-old woman is presented who came to the hospital with a complaining of skin reactions in the thigh area. The clinical findings in this study showed that the scorpion bite site had inflammatory reactions and redness after 24 hours. The patient was treated with Pentavalent anti-scorpion serum by intravenous injection. Approximately one week after the scorpion bite, the local and systemic symptoms disappeared with the use of anti-inflammatory ointments. Immediately after the scorpion bite, the patient's resting place was checked by the companions, and a specimen of the Hottentotta jayakari scorpion species was identified.
Conclusion: Considering that there are scorpion bite in Iran, in order to prevent and control them, it is necessary to increase the general awareness and knowledge of people at risk in society in order to reduce possible risks. In addition to these, increasing the awareness among doctors, especially dermatologists, of the skin symptoms of this dangerous animal, as therapists, can help speed up the treatment process.
