Showing 14 results for Dermatitis
Soodabeh Tirgar-Tabari, Shahnaz Barat,
Volume 1, Issue 4 (12-2010)
Abstract
Background and Aim: Pruritus is usually caused by a primary skin disorder or a systemic disease. Causes of groin pruritus are fungi, eczema, bacterial diseases, neurodermatitis, scabies and many other skin disorders. This study was performed to find the common causes of groin pruritus in female patients that referred to dermatology and gynecology clinics of Yahya-Nejad hospital in Babol.
Methods: This descriptive study was performed on patients with groin pruritus from the begining of winter 2006 until the end of autumn 2007. Other information including name, age, height, weight, previous drug consumption, simultaneous infection in partner or other members of the family, duration of infection, underlying disease and result of examination were recorded in a questionnaire for each patient.
Results: 115 patients were studied. The average age of patients was 41.2 years (15-75 years old). The highest disease frequency was seen in 48 cases (41.7%) in summer. Most cases (33 patients [28.7%]) were between 46-55 years of age. Most of patients (28.7%) had a BMI from 25 to 29.9 (over weigh). The most common causes of groin pruritus in all seasons, ages and BMIs were tinea cruris in 55 cases (47.8%) and seborrheic dermatitis in 29 cases (25.1%).
Conclusion: Considering common causes of groin pruritus, season and patient's weight can be helpful in diagnosis and early treatment of groin pruritus.
Mahnaz Mahmoudi Rad, Akram Miramin Mohammadi, Parviz Tousi, Alireza Firooz, Seyyed Ebrahim Eskandari, Niki Mahmoudi Rad, Yasaman Mirdamadi, Amirhoushang Ehsani, Zeinab Ghasemi, Shima Younespour,
Volume 2, Issue 2 (6-2011)
Abstract
Background and Aim: Malassezia is a lipophilic and dimorphic fungus which has different species. Some of them can be found as natural flora on the skin and in some conditions may cause seborrheic dermatitis. The aim of this study was to identify Malassezia species associated with seborrheic dermatitis in Iranian patients, using PCR-RFLP.
Methods: In this study out of 79 patients with seborrheic dermatitis, isolates of 70 patients were positive for Malassezia species using PCR-RFLP. The Internal Transcribed Spacer 2 (ITS2) region was amplified by PCR employing the ITS3 and ITS4 primers and The restriction endonucleases AluI, BanI and MspAI were selected for producing distinct RFLP patterns.
Results: M. globosa (48.6%), M. furfur (40.0%), M. slooffiae (8.6%) and M. sympodialis (2.8%), were the microorganisms responsible for the infection among participants. M. pachydermatis, M. japonica, M. dermatis, M. restricta, M. obtuse, M. nana and M. yamatoensis were not isolated from any samples.
Conclusion: Our findings suggest that the most common Malassezia species associated with seborrheic dermatitis was M. globosa, followed by M. furfur.
Parvin Mansouri, Soheila Hasouri, Alireza Firooz, Alireza Khatami, Hamed Zartab, Asal Atarod, Reza Chalangari, Katalin Martits Chalangari, Faribroz Sadeghi,
Volume 2, Issue 3 (9-2011)
Abstract
Background and Aim: Atopic dermatitis (AD) is a chronic, relapsing, pruritic skin disease more common in infancy and childhood. Emollients, topical corticosteroids, and avoidance of irritating factors are the mainstay of its treatment, but fear of side effects has limited the use of topical corticosteroids. The objective of this study was to evaluate the safety and efficacy of topical tacrolimus 0.03% ointment in the treatment of AD.
Methods: In this randomized, double-blind, clinical trial, 76 patients with AD older than 2 years were randomly allocated in two groups and treated with either tacrolimus 0.03% ointment (Abu-Rayhan Co., Iran) or placebo, twice a day for 6 weeks. Responses to treatment were compared every 2 weeks using SCORAD.
Results: Twenty-nine patients in tacrolimus group and 26 in placebo group completed the trial. The reduction in SCORAD after 2 and 4 weeks in tacrolimus group was significantly higher than placebo group (P<0/05). The frequency of treatment-induced pruritus and burning sensation was similar in both groups but erythema was more observed in the placebo group (P<0/05).
Conclusion: Tacrolimus 0.03% ointment is more effective than placebo in the treatment of AD.
Ali Ebrahimi, Md, Mansour Rezaei, Phd, Habibollah Khazaei, Md, Hossein Kavoussi, Md, Nooshin Nani,
Volume 4, Issue 2 (6-2013)
Abstract
Background and Aim: Irritant contact dermatitis of hands is a chronic and recurrent cutaneous disorder following the contact with detergents and chemicals. Obsessive compulsive disorder is highly frequent among dermatologic patients, and may be presented with signs of irritant contact dermatitis of hands. The aim of this study was to assess the frequency and relationship between obsessive compulsive disorder and irritant contact dermatitis, among women with chronic and recurrent irritant contact of hands dermatitis in Haj Daie Dermatology Clinic in Kermanshah.
Methods: This case-control analytic study was carried out on 139 females with irritant contact dermatitis of hands and 102 female patients without any history of irritant contact dermatitis of hands. Obsessive compulsive disorder was determined based on the clinical interview using DSM-IV-TR (SCID) by a psychiatrist. Data analysis was performed using chi-square and z-test.
Results: The mean age in the case group was 28.2±8.4 and in the control group was 28.4±6.3 years. Fifty-eight (41.7%) of hand dermatitis patients and 5 (4.9%) of control group had obsessive compulsive disorder (P<0.05). Obsessive compulsive disorder was seen in 29 and 14 patients with moderate and severe irritant contact dermatitis, respectively.
Conclusion: Obsessive compulsive disorder is common in irritant contact dermatitis of hands. Psychiatric evaluation in female patients with chronic irritant contact dermatitis of hands especially moderate and severe forms is suggested.
Ahmad Sarikhani, Hamidreza Mohajerani, Phd, Mowlood Gandomani,
Volume 4, Issue 2 (6-2013)
Abstract
Background and Aim: Seborrheic dermatitis is a chronic dermatitis that has been observed in both neonates and adults. It has been reported following stress, decreasing of mental and somatic energy, tiredness, insomnia, excitability, depression, etc. All of mentioned effects have adverse effects on health activity and result in body weakness. The aim of this study was evaluating general health indices of Arak Islamic Azad university students that suffered from seborrheic dermatitis using Goldberg scale.
Methods: Three hundred and eighteen students were randomly selected and examined, among them 101 students who suffered from seborrheic dermatitis completed the General Health Questionnaire and then the data were statistically described and analyzed.
Results: Forty-one percent of students with seborrheic dermatitis had body symptoms. Anxiety, communicative act failure and depression were observed in 48%, 65% and 31% of patients, respectively.
Conclusion: The findings of this study indicated the strong relationship between seborrheic dermatitis and communicative act failure.
Rouhullah Dehghani, Rezvan Talaee, Fahimeh Chaharbaghi, Nahid Chaharbaghi, Marzieh Firouzi,
Volume 5, Issue 3 (10-2014)
Abstract
Paederus dermatitis is a common dermatitis in northern parts of Iran. Clinically, the most common presentation of paederus dermatitis is sudden onset of erythematous plaques with vesicles. The lesions usually affect exposed areas such as face, neck and arms. It is a common dermatitis between residents and tourists in northern provinces of Iran during spring and summer. Preventive measures include typical insect repellents precautions, such as using bed nets, long-sleeve clothing, and avoiding fluorescent lights. If the beetles are found on the skin, brushing them off, rather than crushing them, helps to prevent the dermatitis. Treatment includes washing the affected area immidiatley, applying cold and wet compresses, and in some cases, treatment with antibiotics, steroids, and antihistamines. Herein, we report a paederus dermatitis case in a 9-year old Kashani boy who had traveled to northern Iran as a tourist. We also review the related literature.
Mahdi Taheri Sarvtin, Mahdi Abastabar,
Volume 6, Issue 1 (4-2015)
Abstract
Malassezia species (previously Pityrosporum) are normal flora of human and warm-blooded animals skin. The genus Malassezia is now divided into 13 species. Most of the yeasts show an absolute requirement for long fatty acid chains and specific procedures are required for their isolation, conservation and identification. Under appropriate conditions, the fungi can cause various skin diseases. The aims of this review were to describe recent classification of genus Malassezia their virulence factors, and their association to dermatlogical diseases.
Setareh Ameri, Taraneh Yazdanparast, Saman Ahmad Nasrollahi,
Volume 7, Issue 2 (7-2016)
Abstract
Background and Aim: Dermatitis or eczema is an itchy skin disorder which is usually caused by the skin inflammatory reaction in response to combination of genetic and environmental factors. This study was aimed to assess the safety of anti-dermatitis creams and possible side effects on human volunteers through measuring the skin biophysical parameters with non-invasive methods.
Methods: Two groups of 15 adults and 15 children as healthy volunteers participated for safety assessment of three anti atopic and contact dermatitis creams. All measurements were done using Cutometer® MPA 580 and the changes in the rate of transepidermal water loss (TEWL), stratum corneum hydration, content of melanin and hemoglobin (erythema) and skin pH were recorded. The obtained data were analyzed using SPSS software version 20 and P<0.05 were considered as significant.
Results: In this trial, no statistically significant changes in skin biophysical parameters including TEWL, melanin, erythema and pH was observed. The stratum corneum hydration on the applicatioins areas of Dermalex Repair Eczema, Dermalex Repair Contact Eczema, Dermalex Repair Eczema for Babies & Children compared to the control sides were significantly different (P=0.002, 0.001 and 0.013). This significant difference was due to emollient or humectant compounds in these creams.
Conclusion: Because of no adverse changes in the skin biophysical parameters, the studied anti-dermatitis creams could be conisdered as safe products. In addition, due to self-assessment results of adverse effects by the participants, no significant adverse effect was seen.
Narges Bidhendi, Hamidreza Ahmadi Ashtiani, Azin Ayatollahi, Somaye Yadangi, Orkideh Ghorban Dadras, Alireza Firooz,
Volume 7, Issue 4 (1-2017)
Abstract
Background and Aim: Dandruff and seborrheic dermatitis (SD) are common chronic skin diseases. There are many chemical drugs for treating dandruff and SD. Prolonged use of them may cause side effects and drug resistance. The aim of this study was to compare the efficacy of a herbal extract lotion with clotrimazole 1% lotion in the treatment of SD.
Methods: Twenty volunteers (12 men and 8 women) aged 20 to 40 years, with seborrheic dermatitis were enrolled in this trial and were randomly allocated into two groups. One group was treated with a herbal extract lotion and the other group with clotrimazole lotion. The herbal extract contained common sage, thyme vulgaris, tea tree oil, lavender, willow, rosemary, and aloe vera. The patients were instructed to use the lotions three times a week for 4 weeks. We evaluated the patients by clinical assessment and measured the scalp sebum, pH, and dandruff number before two weeks, and four weeks after completed a treatment. At the end of the study, each participant satisfaction form.
Results: At the end of the study, the participants whom received the herbal extract lotion had a significantly greater reduction in scalp scaling, erythema, itching, and number of dandruff compared with those who received clotrimazole (P<0.05). The patient satisfaction score was also higher in the herbal extract group (60% versus 10%).
Conclusion: This study showed that herbal extracts lotion was effective in the treatment of dandruff and seborrheic dermatitiand can be an appropriate alternative to chemical agents.
Pedram Alirezaei, Zeinab Memarzadeh, Sara Molkara, Seyedeh Fatemeh Yaghoubi Al,
Volume 10, Issue 1 (4-2019)
Abstract
Background and Aim: Seborrhoic dermatitis is one of the most common diseases in dermatology with a prevalence of about 2%. Many treatments have been used for this disease. This Study aimed to investigate the efficacy of betamethasone lotion compared with clotrizone lotion in patients with seborrheic dermatitis of face and scalp.
Methods: This double blind study was performed on 60 patients with seborrheic dermatitis older than 18 years, who refered to Emam Reza hospital, Mashhad. Patients were divided into two groups: clotrizone (31) and betamethasone group (29 patients). Patients were treated for a month. We evaluated severity of pruritus, erythema and desquamation of the face and scalp.
Results: The average age of patients participating in the study was 33.1 years (18 to 56 years) and 56.7% of patients were male. No significant differences were found in age and gender between the two groups (P> 0.05). Both treatments reduced severity of erythema and desquamation of the face and scalp (P<0.001). Two weeks after treatment, clotrizone had better performance, but there after both lotions had similar effect. Betamethasone reduced pruritus more than clotrizone.
Conclusion: This study showed that both betamethasone and clotrizone were effective. Clotrizone has better impact on the severity of erythema and scaling and betamethasone has better effect on improving the severity of pruritus.
Esmaeil Alizadeh, Abbas Aghaei Afshar, Mohammadamin Gorouhi, Leila Shirani Bidabadi, Zahra Nadalian,
Volume 10, Issue 4 (1-2020)
Abstract
Introduction: Egyptian cockroach is one of the species of cockroaches, which has a worldwide distribution, and can live in closed human environments. In this paper, we present the first reported patient with skin reactions and dermatitis to Egyptian cockroach in Iran.
Case Report: An 80-year-old man referred to the clinic with skin lesions on his right foot. The patient lived in an adobe house in Rafsanjan city, and he had not past history of skin lesions. He reported severe itching at the beginig,one day later redness and swelling appeared. Physical examination, revealed inflammation and bite signs. Lesions disappeared after two weeks of medical treatment.
Conclusion: In general, cockroaches can cause skin reactions after body contact, so public knowledge and awareness about the prevention and control of these cockroaches should be increased in the community.
Maryam Ghiasi, Mahshidsadat Ansari, Maryam Nasimi, Farnaz Pourrajab,
Volume 12, Issue 2 (8-2021)
Abstract
Background and Aim: Atopic dermatitis is a chronic inflammatory disease that is caused by an inflammatory process stimulated by Th2 cells. Acne vulgaris is a chronic inflammatory skin disease. It is associated with an increase in sebum secretion, unusual pilosebaceous keratinization and an increased inflammatory immune response. Propionibacterium acne can induce IL-17 production and Th1/Th17 response. The present study was designed to determine the prevalence of atopic dermatitis in patients with acne.
Methods: In this case-control study, the case group consisted of 75 individuals with acne and the control group consisted of 75 individuals without acne matched in age and gender. Both groups were interviewed for atopic dermatitis, asthma and allergic rhinitis symptoms in the past and present.
Results: Prevalence of atopic dermatitis at present in patients who had acne was significantly lower than those who did not have acne. There was no significant difference between case and control groups in frequency of atopic dermatitis in the past and frequency of asthma and allergic rhinitis in the present and past time.
Conclusion: The inverse relationship between prevalence of acne and atopic dermatitis can be related to activation of different immune responses (Th1 versus Th2), but more studies should be done to confirm this relationship.
Hasti Ahmadian Yazdi, Alireza Firooz, Mohsen Rezaeian Vaghar, Elahe Kashani, Aniseh Samadi,
Volume 14, Issue 2 (8-2023)
Abstract
Background and Aim: In order to overcome the local side effects of the conventional treatments for atopic dermatitis, a new attitude regarding alternative treatments would be needed, which herbal medicines are promising approachs in this case.
Methods: It was a 4-week, before-after clinical study, conducted on 20 participants (16 women and 4 men) aged 39.95±11.04 years. The severity scoring of atopic dermatitis was determined based on total & local SCORAD. skin biophisical parameters including TEWL ,skin hydration, pH, temperature, sebum and skin erythema were also measured after 2 and 4 weeks application of the study product. Participants’ satisfaction as well as tolerability of the product were assessed by monitoring the adverse effects.
Results: A significant improvement was detected in LOCAL and TOTAL SCORAD at weeks 2 and 4 (P<0.01). The intensity of burning and pruritus also showed a significant decrease at weeks 2 and 4 (P<0.01). A significant increase in the skin hydration was shown at weeks 2 and 4 after treatment (P<0.01). 84.1% and 78.9% of participants described their skin lesions as "improved" or "much improved", 2 and 4 weeks after treatment respectively.
Conclusion: The test cream containing oats and chamomile extract is considered a safe and effective product for improving mild to moderate lesions of atopic dermatitis.
Azin Ayatollahi,
Volume 14, Issue 3 (11-2023)
Abstract
Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder characterized by intensely itchy eczema. Sensitivity to Malassezia species may be associated with the severity of AD symptoms. The growth conditions for Malassezia spp. on children's skin are lower than on adult skin, making adults more susceptible to Malassezia. There is a minor suspicion that Malassezia spp. plays a role in AD as it may interact with skin immune reactions and barrier function, and sensitization against this skin-colonizing yeast can be correlated with illness activity. Additionally, antifungal treatment shows beneficial effects in some patients. However, the pathogenetic process and mutual interaction between Malassezia spp. and AD remain relatively unclear, necessitating further research.
