Showing 11 results for Diagnosis
Narges Alizadeh, Rasool Hassanzadeh, Sina Khajeh Jahromi, Mohsen Taherkhani,
Volume 3, Issue 3 (9-2012)
Abstract
Hair loss can be viewed a problem from different perspectives: as a disease, a disorder which affects appearance of an individual, and its psychological effects. Therefore, it is crucial to determine the causes and types of hair loss. This review summarized hair loss evaluation methods with significant emphasis on their clinical aspects. According to relevant literature reviews, the major approaches to hair loss are taking medical history, primary investigations and detailed hair examination. Although several invasive and non-invasive, clinical and paraclinical examinations can be used for hair loss assessment, it is generally accepted that using clinical evaluation methods and physical examinations are more efficient. In conclusion, diagnosing hair loss is complex and sometimes time-consuming process. However, precise hair examination may lead to the suspicion of an endocrine disorder.
Zahra Hallaji, Alireza Khatami, Reza Robati, Hassan Seirafi, Alireza Firooz, Vahideh Lajevardi, Zoherh Mozafari, Parvin Mansouri, Pedram Mehryan, Mansour Nassiri-Kashani,
Volume 6, Issue 1 (4-2015)
Abstract
Urticaria is a common and challenging skin disorder. Its diagnosis and treatment is not limited to the field of dermatology. General physicians, and allergologists and clinical immunologists are also commonly involved in the management of urticaria patients.
One of the missions of the Iranian Society of Dermatology is to develop strategies to provide the best possible management for patients suffering dermatological conditions. To accomplish this mission, the Society assigned a committee to search and critically appraise the recent research evidence and available guidelines to develop a clinical practice guideline concerning diagnosis and treatment of urticaria.
Azita Nikoo, Babak Hosseindoost, Alireza Khatami,
Volume 6, Issue 1 (4-2015)
Abstract
Background and Aim: Mycosis fungoides (MF) is the most common primary cutaneous lymphoma. Diagnosis of early MF (eMF) is often difficult due to its resemblance of benign dermatoses. The aim of this study was to evaluate the role of provided clinical information on the histopathology request forms for diagnosis of eMF according to the International Society of Cutaneous Lympoma (ISCL) criteria.
Methods: In this cross-sectional study, 108 patients admitted to Razi Hospital, Tehran, between April 2012 and November 2013, who were biopsied as eMF cases, were recruited. Based on partial application of ISCL algorithm, the checklist of clinical and histopathological findings were scored.
Results: Eighty-five (78.7%) patients received maximum total clinical and histopathological scores (4) and their eMF were definitely diagnosed. Sixteen (14.8%) patients received a total score of 3, and suggestive eMF diagnosis was made. Further work up such as immunohistochemistry (IHC) evaluation were recommended. Seven patients (6.5%) received a total score of 2, which did not confirm eMF diagnosis. Follow up was recommended. In 14 (87.5%) of 16 patients who had received a total score of 3, the definite diagnosis of eMF was made according to the results of IHC. They were referred to receive treatment. In 2 patients (12.5%) diagnosis of eMF were not confirmed by IHC. They were recommended to undergo polymerase chain reaction (PCR) evaluation
Conclusion: Many MF cases can be diagnosed in the early stages using a combination of clinical and histopathological criteria.
Azam Habibi, Mahmoud Nateghi Rostami, Masoumeh Douraghi, Masoumeh Dolati, Batool Hossein Rashidi, Roghaye Ahangari,
Volume 6, Issue 4 (1-2016)
Abstract
Background and Aim: Trichomonas vaginalis infection is one of the most common sexually transmitted diseases of women and men in the world. To the best of our knowledge, there has been no previous report of the prevalence and complications of trichomoniasis in women of Qom.
Methods: In this cross-sectional study, the prevalence of T. vaginalis in women whom were admitted to a referral gynecology clinic in the city of Qom. For this purpose, two diagnostic methods, wet mount and ITS-PCR, were used to examin the vaginal swabs taken from the participants. Microscopic examination of cellular morphology and bacteria was also conducted on the stained smear.
Results: Three hundered volunteers were enrolled. Of 300 specimens, 7 (2.67%) by wet mount and 34 (11.3%) by ITS-PCR method were positive. The positive results of ITS-PCR were confirmed by sequencing of PCR products. In comparison with women without T. vaginalis infection, infection with T. vaginalis was associated with increased the risks of low birth weight (OR=43.3; 95% CI=2.8-671.9), in women with history of abortion (OR=91.8; 95% CI=15.5-544.2), and in women with premature rupture of membrane (PROM) (OR=21.6; 95% CI=2.1-22.9). Probability of finding of epithelial cells (OR=36.9; 95% CI=6.9-197.3) and white blood cells (OR=43.3; 95% CI=2.8-665.1) in stained smear were higher in women with T. vaginalis compared to those without T. vaginalis.
Conclusion: Comparing with wet mount, ITS-PCR seems to be a more sensitive and reliable technique in detection of T. vaginalis infection in women. The high prevalence of trichomoniasis emphasizes the need for screening of women in Qom. Early examination and accurate diagnosis of T. vaginalis, especially in middle-aged women, could prevent pregnancy-related complications of T. vaginalis.
Fatemeh Valipoori Goodarzi, Javad Haddadnia, Maryam Hashemiyan,
Volume 6, Issue 4 (1-2016)
Abstract
Background and Aim: Malignant melanoma is one of the most dangerous types of skin cancer. The aim of this study was to evaluate Spatial Thermographic Imaging (STI) in differentiating benign from malignant skin lesions.
Methods: One-hundred and ten STI images were taken from the volunteers who had lesions being suspected for malignant melanoma. Benignity or malignancy of lesions was determined according to the changes detected in tissue using texture filters. The STI data were compared with histopathology results.
Results: Out of 110 investigated patients with STI, three cases of malignant melanoma were found. Two cases were in men and the other one was in a woman. Accuracy of STI in diagnosis of malignant melanoma was 98%.
Conclusion: STI may potentially be used as a non-invasive method for the detecting skin malignant melanoma.
Khadijeh Tavakoli, Zahrabeigom Moosavi Moosavi, Kambiz Kamyab,
Volume 9, Issue 2 (7-2018)
Abstract
Introduction: Idiopathic granulomatous mastitis (IGM) is a rare benign breast disease. The importance of this disease relies on its similar clinical manifestation to those of mammary carcinoma and a group of mastitis with other causes.
Case Report: The patient was a 32-year-old woman, that suddenly got fever, pain and swelling in left breast. In examination several masses were felt. Performed core needle biopsy reported IGM.
Conclusion: Similarity of clinical presentations and diagnostic tests to the other kinds of mastitis and malignancies may lead to misdiagnosis and mistreatment, which imposes socioeconomic and psychological burden to patients.
Alireza Firooz, Vahideh Lajevardi, Parvin Mansouri, Nassiri-Kashani Mansour, Yasaman Norouzi, Farhad Handjani,
Volume 9, Issue 3 (10-2018)
Abstract
Urticaria is a common and challenging skin disorder. Diagnosis and treatment of urticaria is not limited to the field of dermatology. General physicians, allergologists and clinical immunologists are also commonly involved in the management of patients with urticaria.
Iranian Society of Dermatology developed a clinical practice guideline concerning diagnosis and treatment of urticaria that was published in 2015. The current guideline, with respect to scientific papers that got published from 2015 to August 2018, is the update it.
Ensieh Lotfali, Akram Miraminmohammadi, Mahshid Shahrzad, Ali Khamesipoor, Alireza Firooz, Azam Fattahi,
Volume 11, Issue 1 (4-2020)
Abstract
Background and Aim: The aim of the present study is rapid and precise identification of yeast species isolated from nail of patients with clinical features of onychomycosis using PCR-RFLP technique.
Methods: 50 patients with involvement of 29 fingernails and 21 toenails were enrolled in the study. Different yeast species were identified by conventional mycological. The PCR-RFLP was tested on yeast isolated and the PCR-RFLP products were separated by electrophoresis in 2% agarose gel, with DNA stain.
Results: The main causative agents were yeasts in 12 cases (24%). Candida albicans was the most commonly isolated yeast species followed by Candida parapsilosis (6%), and Candida glabrata (4 %).
Conclusion: PCR-RFLP method using ITS1-ITS4 primers and MspI restriction enzymes is a rapid, accurate and cost-effective method for specific diagnosis of the most prevalent candida spp. Its ability to detect low amounts of fungal DNA in patient samples in 6-8 hours could be useful for clinical laboratories for optimal management of these infections.
Farasat Noormohammadifar, Alireza Soltanian, Pedram Alirezaei,
Volume 11, Issue 3 (10-2020)
Abstract
Background and Aim: Trichoscopy is a non-invasive diagnostic tool for hair diseases. The aim of this study was to evaluate the trichoscopic findings in different types of alopecia.
Methods: This cross-sectional study was conducted on 155 alopecia patients referring to Hamadan’s Sina hospital from March 2019 to July 2020. The patients were recruited after giving written informed consent. Scalp biopsy was performed to confirm the diagnosis and trichoscopic evaluation was then carried out. Trichoscopic findings along with demographic data were recorded. Data was analyzed using SPSS 16.0 software and appropriate statistical methods.
Results: A total of 155 patients including 79 males and 76 females were included in the study. The most common trichoscopic finding in alopecia areata was vellus hair (95.5%). The most common finding in androgenetic alopecia (AGA) was hair shaft thickness heterogeneity which was observed in all AGA patients. The most common findings in telogen effluvium (TE) were single hair pilosebaceous units, peripilar sign, thin terminal hairs and upright regrowing hairs which were observed in all TE patients. The most common finding in lichen planopilaris was perifollicular scaling (81.8%). The most common findings in discoid lupus erythematosus were large yellow dots (100%) and fine scaling (100%). Black dot was the most prevalent finding in tinea capitis (85.7%).
Conclusion: Trichoscopy ,as a non-invasive tool, could be helpful in differentiating different types of alopecia.
Fatemeh Mohaghegh, Zahra Talebzadeh, Mahsa Bahraminejad,
Volume 11, Issue 4 (1-2021)
Abstract
Introduction: Tinea capitis is the most common skin infection on the scalp and an uncommon dermatophytosis in adults. Its clinical appearance varies greatly depending on the causative organism, the type of hair involvement and the extent of the patient inflammatory response. Its common features are fragmented hair loss with varying degrees of scaling and erythema. However, if the clinical symptoms are mild, the diagnosis can be challenging.
Case report: We report a case of tinea capitis in a 60-year-old woman who initially had few clinical symptoms and according to the biopsy result and the presence of fibrosis, lichenpilanopilaris (LPP) were diagnosed and she received related treatment with methotrexate and cyclosporine, but after 4 months, no response to treatment and exacerbation of symptoms were observed. Tinea capitis was diagnosed and the patient was given appropriate treatment.
Conclusion: Tinea capitis can imitate clinical features of lichenplanopilaris and mistreatment with corticosteroids can lead to extension of the disease.
Amirhoushang Ehsani, Arezou Jammanesh, Amirali Jahanshahi, Elnaz Khosravani, Reza Robati, Zahra Saffarian, Alireza Firooz, Vahide Lajevardi, Parvin Mansouri, Mansour Nassiri Kashani,
Volume 13, Issue 4 (2-2023)
Abstract
Urticaria is a common and challenging skin disorder. Diagnosis and treatment of urticaria is not limited to the field of dermatology. General physicians, internal medicine specialists, allergologists and clinical immunologists are also commonly involved in the management of patients with urticaria.
Iranian Society of Dermatology developed a clinical practice guideline concerning diagnosis and treatment of urticaria that was published in 2018. The current guideline is the result of scientific papers that got published from April 2018 to August 2022.
