Amir Houshang Ehsani, Hossein Mortazavi, Pedram Noormohammadpour, Arghavan Azizpour, Sara Rostami, Maryam Nasimi,
Volume 7, Issue 2 (7-2016)
Abstract
Background and Aim: Acne vulgaris is a common skin disorder. This study was conducted to evaluate the impact of Ramadan fasting on acne healing in patients admitted to the dermatology clinic, Razi Hospital, Tehran.
Methods: In this prospective cohort study, 10 fasting persons (9 women and 1 man) and 10 non-fasting persons (9 women and 1 man) with acne were studied. Their baseline acne severities were recorded and acne improvement was evaluated in both groups after Ramadan month.
Results: Acne improvement was 71% in fasting persons and 49% in non-fasting persons. Improvement in fasting persons i.e. was 1.4 times of non-fasting ones (P=0.158). However, no significant statistical difference was detected. Also, it was determined that improvement was different according to acne grading. Improvement in acne lesions in patients with grade 2 severity was 100%, in those with grade 3 acne was 78%, and in patients with grade 4 acne was 35 % (P=0.025). But in non-fasting patients there was not a statistical difference between acne severity and improvement rate. Furthermore in patients younger than 24, improvement rate of acne was 1.6 fold more than non-fasting persons and in patients older than 24, this ratio was 1.3 (P=0.011).
Conclusion: This study did not show any statistically significant difference in acne improvement between who were fasting and who were not during Ramadan. Studies with larger sample size are recommended.
Erfan Zamani, Shayan Zamani, Mansour Nassiri Kashani, Alireza Firooz,
Volume 15, Issue 3 (11-2024)
Abstract
This review study examines the effects of oral collagen supplementation on various biophysical properties of the skin, including hydration, elasticity, and wrinkle reduction. Collagen, as the most abundant structural protein in the skin, plays a vital role in maintaining its firmness, elasticity, and moisture. With aging, collagen production declines, leading to visible signs of aging such as wrinkles, sagging, and dryness of the skin. Additionally, factors like UV radiation and environmental pollutants accelerate collagen degradation, contributing to premature skin aging. In recent years, oral supplements containing hydrolyzed collagen, particularly collagen peptides, have gained significant popularity due to their potential ability to stimulate collagen production and improve skin quality. Various studies indicate that regular consumption of these supplements can significantly increase skin hydration, enhance elasticity, and reduce the depth and number of wrinkles. However, there are notable limitations in the existing studies, including variations in dosage, intervention duration, and collagen sources. Moreover, many of these studies have small sample sizes and short intervention periods, which limit the validity of the results. Additionally, the presence of other ingredients, such as vitamin C and hyaluronic acid in some supplements, makes it challenging to isolate the direct effects of collagen. Despite these challenges, the existing evidence suggests that oral collagen supplementation holds high potential as an effective approach for addressing skin aging. However, further long-term studies with larger sample sizes and more diverse populations are necessary to determine the precise mechanisms and optimal dosage, thereby providing more definitive scientific recommendations.
