Showing 9 results for Hair
Mohammadali Nilforoushzadeh, Seyyed Mohsen Hosseini, Farahnaz Fatemi Naeini, Fariba Jaffary, Elaheh Haftbaradaran, Narges Rahmanian, Fatemeh Hashemi, Maryam Vatankhah,
Volume 1, Issue 3 (9-2010)
Abstract
Background and Aim: Androgenetic alopecia is an extremely common disorder affecting both men and women. The incidence is generally considered to be greater in males than females, although some evidence suggests that the apparent differences in incidence may be a reflection of different expression in males and females. This genetically determined disorder is progressive through the gradual conversion of terminal hairs into indeterminate hairs and finally to vellus hairs. Patients have a reduction in the terminal-to-vellus hair ratio, normally at least 2:1. Following miniaturization of the follicles, fibrous tracts remain. Patients with this disorder usually have a typical distribution of hair loss.
Methods: This is a cross sectional study that conducted in Isfahan health center in 2007-2008 .Using simple random sampling, we selected 1800 women in urban health center areas for hair loss. We evaluated the type of hair loss by Ludwig classification. The data was collected through administration of a specifically designed questionnaire and was analyzed using SPSS software. The chi-square and student tests were used for data analysis.
Results: According to results of this study the of 1800 women, 712 (39.6%) had hair loss. Mean age of females who had hair loss was 50.4±13 years.
Conclusion: Thyroid disorders, ferritin serum level and androgenic hormones may play role in hair loss and their existance should be assessed.
Fatemeh Heidari, Abazar Yari, Maliheh Nobakht,
Volume 6, Issue 3 (10-2015)
Abstract
Emergence and spread of various diseases in the past century have been associated with many problems for the health care providers. Now a days, with advancement of technology, new methods such as cell therapy, are available, efficient and successful in some clinical areas. To use any cell, it is necessary to identify its source, so herein, we reviewed the literature of a new source of adult stem cells in the bulge of hair follicle.
Hair is composed of two parts: root and shaft. Proximal two-thirds of the hair root, called hair follicle that is surrounded by two dermal and epidermal sheaths. Epidermal sheath included inner and outer root sheath. Outer root sheath at the junction of the errector pilli muscle and sebaceous glands make the bulge that includes stem cells.
In this review we described anatomy of the hair follicle, hair growth cycle, hair follicle bulge, embryonic source of hair follicle, isolation of bulge stem cells using cell surface markers, gene expression and differentiation in bulge stem cells directing differentiation of bulge stem cells in normal skin repair, and practical advantages of bulge stem cells over other stem cells.
Mohamad Ebrahimzadeh Ardakani, Ghasem Dastjerdi, Fatemeh Sahraie, Parvneh Dehqan Harati,
Volume 7, Issue 1 (4-2016)
Abstract
Background and Aim: Hair loss is a chronic and frequent dermatological condition. It negatively affects the psychological status, social relationships and daily activities of the patients The aim of this study was to evaluate the prevalnce of depression in women with hair loss in a referral dematology clinic in Yazd, Iran.
Methods: This cross-sectional study was conducted from March 21 to June 21, 2015. Fifty-four women suffering from hair loss referred to the Shahid Sadoughi Dermatology Clinic in Yazd were recruited. Depression assessed by using the Beck Depression Inventory. Data were analyzed using versioin 18 of PASW (IBM Corp., Armonk, NY, USA) and Fisher's exact test was used for comparing proportions in different groups.
Results: The mean ± standard deviation score of depression was 16.1±13.5. The study showed that 67% of hair loss patients were experiencing depression. While not statitically significant, frequency of depression seems to be associated with the level of education (P=0.052). There was no associatioin between the frequency of depression and age, marital status, previous medical history, or drug use.
Conclusion: This study showed that depression is highly frequent among women with hair loss. Beauty is crucial for most women and feeling the lack of beauty and not being attractive decrease their social interaction. More effective treatment of hair loss may improve depression and community relations, and consequently result in higher quality of life in a hair loss patient.
Shokoufeh Ahmadi Moghadam, Roghieh Jebreili, Masoumeh Yarjanli,
Volume 7, Issue 2 (7-2016)
Abstract
Background and Aim: Hair loss is a common issue among men and women. Studies have shown that 1-25 (OH) vit D affects differentiation in normal follicles and hair growth, through effect on the translation of genes. The aim of this study was to assess vitamin D3 level in patients suffering from hair loss between the age of 18 to 50 years.
Methods: This cross sectional study was conducted on 100 patients including 27 men and 73 women suffering from hair loss. Cases were chosen from one of the educational hospitals of Islamic Azad University, Tehran Medical Branch. Blood samples were obtained from the patients and were sent to the laboratory for assessment of vitamin D3 serumic levels.
Results: The average of patients’ age was 29.5±8.5 years. The average serum level of vitamin D in patients was 17.26±14.5 ng/mL. Sixty-six percent of patients suffering from hair loss had vitamin D deficiency as well. The prevalence of vitamin D insufficiency in women was considerably more than men (P<0.001).
Conclusion: Prevalence of vitamin D deficiency among people suffeing from hair loss is noteworthy.
Mohsen Sheykhhasan, Hossein Bakhtiari Pak, Mahdieh Ghiasi,
Volume 7, Issue 3 (10-2016)
Abstract
Platelet-rich plasma (PRP) is a solution derived from whole blood that is enriched in the platelet fraction. Platelets serve as a reservoir of growth factors and cytokines. When platelets are activated in vivo, signaling molecules are released into the immediate microenvironment and activate receptors for various pathways. PRP has been applied to bedsores to promote healing. Over the last decade, it has been used as a valuable therapeutic method in various specialties such as maxillofacial surgery, plastic surgery, orthopedics and sports medicine. Only recently has PRP been utilized for dermatologic purposes, psrticularly, for the treatment of male and female pattern hair loss.
In this review, we discuss molecular and cellular pathways up-regulated by PRP important in hair folliculogenesis, and examine clinical evidence from all previously published studies involving the use of PRP for pattern hair loss.
Rozita Davoodi, Rafat Gerayeli, Elnaz Soltani, Najmeh Mohajeri, Zahra Khani, Nahid Jalalian Elahi,
Volume 9, Issue 4 (1-2019)
Abstract
Background and Aim: Among destructive treatments for removal of unwanted hair, hair removal laser devices have widely replaced the old fashion methods due to their safety and effectiveness. The purpose of this study was to analyze the effective factors on treating unwanted hairs with a laser device.
Methods: This retrospective study, was performed on records of 122 patients who referred to a hair and skin clinic .Patients with hirsutism or other diseases were excluded. Hair thickness and color, skin color, number of laser sessions, age and sessions interval were evaluated. The collected data were analyzed by compeutering program SPSS version 21, analytic tests chi-square and logistic regression (P less than 0.05 considered meaningful).
Results: The average age of participants was 31.3±6.6 years. The average number of laser sessions was 5.4±2.1 and the most satisfying outcome was observed in dark hairs and more than 5 sessions (P<0.05). Multivariate logistic regression model illustrated that the number of sessions directly impacts the effectiveness of treating unwanted hair (P<0.05). Level below the rock curve and the sensitivity were 0.71(0.61-0.81) and 0.759, respectively.
Conclusion: This study showed that hair thickness and color, number of laser sessions are important factors on hair removal treatments by laser. For optimal outcome more sessions with longer follow up is recommended.
Sepehr Zargaran, Soroush Mohitmafi, Ali Anisian,
Volume 12, Issue 1 (5-2021)
Abstract
Background and Aim: Alopecia by reduction of hair follicles at the wound healing site is a complication of cryosurgery that creates an unpleasant appearance in the scar of healed tissue. The aim of this study was to evaluate the effect of low level laser on preventing necrosis of hair follicles and increasing hair follicles in cryosurgery induced wounds.
Methods: Fifty male Wistar rats were randomly divided into 2 main experimental and control groups (with and without low power laser) and 5 subgroups. Histopathological examination of the amount of hair follicle count and angiogenesis at intervals of 3, 7, 14, 21 and 28 days was performed in the laboratory. SPSS software was used for statistical analysis.
Results: There was no significant difference in the angiogenesis had significantly index between the main groups on days 14 and 21 (P>0.05), but on days 3, 7 and 28, the experimental group had significantly higher angiogenesis than the control group. Throughout the days, both groups showed a significant increase in angiogenesis (P<0.05), except for the third and seventh days in the control group, and in both groups between the 21st and 28th days (P>0.05). In the comparison of hair follicle index, there was an increase on all days, which was significantly higher in the experimental group than the control group (P<0.05). However, no statistical difference was observed between the third and seventh days (P>0.05).
Conclusion: The use of low-power lasers on cryosurgery induced wounds with scars and alopecia can prevent hair follicles necrosis and subsequent increase in their numbers in rats.
Zahrabeigom Moosavi, Alireza Firooz,
Volume 12, Issue 4 (2-2022)
Abstract
The COVID-19 pandemic is still present and we are directly or indirectly affected by it. The skin is one of the organs that has some manifestations not only during the course of the disease, but also long after recovery and also after vaccination. Hair is one of the parts that, like the skin, may show disorders during and after recovery of the infection and also after vaccination. In this issue, we aimed to provide an overview of the effects of COVID-19 and vaccination on hair. We also express the instrumental role of hair in the study of other diseases, including psychological problems.
Azin Ayatollahi, Taraneh Yazdanparast, Saman Ahmadnasrollahi, Mahsa Fattahi, Mahdieh Emambakhsh, Alireza Firooz,
Volume 13, Issue 1 (5-2022)
Abstract
Background and Aim: Hair loss is one of the most common problems among the skin and hair related diseases. Hair loss can lead to anxiety, depression, low self-esteem and dissatisfaction with appearance.
Methods: Patients with androgenetic alopecia who met the eligibility criteria entered the study. Participants were asked to randomly apply a solution of valproic acid 8.3% or a solution of minoxidil 5% on the affected areas according to the treatment protocol (twice a day). Before and 2 months after treatment, the participants were evaluated. The studied indices included the number of hair follicles in the specified area, the number of velus hairs, the number of terminal hairs, the average hair thickness, and the percentage of hairs in the anagen and telogen phases, as well as the skin reactions in the area. Hairs were examined at the beginning of the study and at 2 months after treatment using Foto Finder-trichoscale device.
Results: Two months after treatment compared to baseline in the valproic group, anagen hair count index (P=0.02), general hair count index (P=0.03), and terminl hair count index (P=0.012) showed significant changes. While telogen hair count (P=0.059) and vellus hair count (P=0.097) did not show significant changes. These changes were more significated in minoxidil group.
Conclusion: 8.3% valproic acid solution showed positive effects in increasing the number of hairs and decreasing the percentage of telogen hairs. Due to the delayed mechanism of valproic acid, the duration of treatment with this compound should be considered longer than minoxidil as a positive control.
