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Showing 2 results for Hyperpigmentation
Quality of life in women with melasma
Hossein Safizade, Simin Shamsi-Meymandi, Yalda Bani-Hashemi,
Volume 1, Issue 4 (12-2010)
Abstract

Background and Aim: Melasma is an acquired symmetrical brown hyperpigmentation of the face or neck. Melasma has been shown to have a significant emotional and psychologic distress on affected patients. Although this pigmentary disorder is more prevalent among women of reproductive age, the effect of melasma on quality of life in this population is unknown. The aim of this study was to evaluate health-related quality of life in patients with melasma attending to dermatology clinics in Kerman city, Iran.

Methods: A cross-sectional study was carried out by clinical examination and questionnaire on 200 patients with melasma. Melasma area and severity index (MASI), Dermatology Life Quality Index (DLQI) and Melasma Quality of Life Scale (MELASQOL) were used to assess melasma severity and quality of life.
Results: There were 200 women with mean age 31.86±6.42 years old (range: 18-55 years). The mean score of DLQI and MELASQOL were 6.90±4.48 and 40.24±14.95, respectively. In 113 (56.5%) patients, melasma had very large effect on their quality of life. There was a significant correlation between the scores of quality of life questionnaires and MASI (P<0.001). In DLQI scale the most frequent impairment was related to emotional well-being and based on MELASQOL questionnaire, embarrassment due to skin appearance had an important impact on quality of life.
Conclusion: This study revealed that physicians must consider the devastating psychosocial impact of pigmentary imperfections in addition to pharmacological and physical treatment.


Efficacy of laser therapy in the management of melasma and skin hyperpigmentation: a descriptive review
Hassan Mohsen, Elaheh Nahvifard, Armin Nazemi Zadeh, Afshan Shirkavand, Leila Ataei Fashtami,
Volume 16, Issue 4 (2-2026)
Abstract
Melasma is one of the most common disorders It is an acquired skin pigmentation that occurs especially in sun-exposed areas, mainly on the face. The chronic, recurrent nature and multifactorial pathophysiology of this disease make its treatment associated with significant challenges. In recent years, lasers have been considered as new and complementary methods in the treatment of melasma, but the results reported in different studies have been variable.
The aim of this study is to review the studies conducted on the role of various lasers in the treatment of melasma and compare their effectiveness, safety and limitations. This study was conducted as a review and published articles on the use of various lasers including Nd: YAG, fractional lasers, picosecond lasers, pulsed-dye lasers (PDL) and intense pulsed light sources (IPL) were examined. The findings of the studies were analyzed and compared descriptively.
The results of the review of studies showed that lasers can reduce the severity of melasma and improve the appearance of skin lesions, but the degree of effectiveness and durability of results depends on the type of laser, treatment parameters, patient skin type and compliance with post-treatment care. Among the various methods, the low-fluence Nd: YAG laser has shown the most scientific evidence in terms of the balance between effectiveness and safety. However, the risk of recurrence and complications such as post-inflammatory hyperpigmentation remain important challenges for laser treatment of melasma.
Overall, the available evidence suggests that lasers have an effective role in the management of melasma, but the best results are achieved when these methods are used as part of a comprehensive and combined treatment approach, along with topical treatments and appropriate sun protection.
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