Masoud Golpour, Mehrdad Taghipour, Fariborz Azizi, Lotfollah Davoudi,
Volume 5, Issue 3 (10-2014)
Abstract
Psoriasis is a chronic inflammatory disease which may occur in childhood. In many psoriasis cases, the disease develops in individuals younger than 18 years old. Psoriasis in children presents with a variety of clinical manifestations. Becouse of its atypical presentations, early diagnosis of psoriasis is difficult in children. The plaque type psoriasis is the most common form of the disease in children. Different treatments such as phototherapy and systemic therapies have been proposed, but using any of them leads to serious complications in children. Therefore, early diagnosis and proper management of the disease are the main components of the treatment in pediatric psoriasis cases. Herein, we aimed to provide a general overview on the pediatric psoriasis, including its epidemiology, pathogenesis, clinical manifestations as well as the treatment and discussing the latest related information.
Maryam Nourizadeh, Mahsa Fattahi,
Volume 14, Issue 4 (2-2024)
Abstract
Methotrexate (MTX) is a freely available medication. However, regardless of extensive off-label consumption, FDA labeling does not include accepted for the consumption of MTX for many inflammatory skin diseases in pediatrics, containing morphea, psoriasis, atopic dermatitis, and alopecia areata. Lacking published healing recommendations makes the clinicians unsure about prescribing MTX in an off-label manner especially in children. Present study, was conducted to review the use of MTX to heal pediatric inflammatory skin disorders.
The evidence and consent based advices will assistance safe and successful use of MTX for the underserved population of pediatrics who may benefit from this valuable, time-honored medication.
