Showing 25 results for Psoriasis
Masoumeh Barzegari, Zahra Hallaji, Amirhoushang Ehsani, Pedram Nourmohammdpour, Maedeh Parham,
Volume 1, Issue 2 (6-2010)
Abstract
Background and Aim: Psoriasis is a chronic skin disorder involving many parts of the body including skin, nails and joints with severe negative effects on patient's quality of life. Nail involvement is one of the most difficult involvements of this disease to treat. Psoriatic arthritis categorized in sero-negative spondilo-arthropaties with some deforming characteristics. The aim of the present study was to evaluate the relationship between psoriatic arthritis and nail involvement based on standard psoriatic nail involvement score (NAPSI).
Methods: Psoriatic patients visiting dermatology clinic of Razi hospital were selected. Patients with arthritis enrolled as the case group while patients that had no joint involvement participated in control group. After matching, demographic data of both groups as well as NAPSI score and nail involvement characteristics collected through special questionnaires and analyzed with SPSS version 14.
Results: A total of 30 patients with psoriatic arthritis and 75 patients without arthritis were enrolled the study. Analysis of collected data demonstrated that nail involvement among patients with psoriatic arthritis (mean NAPSI score=46) was more common and severe than patients without joint involvement (mean NAPSI score=9.23) (P<0.05).
Conclusion: It seems that there is a significant difference between psoriatic patients presenting with or without arthritis and presence of arthritis probably can determine occurrence and extension of nail involvement.
Soodabeh Zandi, Simin Shamsi Meymandi, Sadegh Hasheminasab Gorji, Fatemeh Sabouri Shahrebabak,
Volume 2, Issue 3 (9-2011)
Abstract
Background and Aim: Psoriasis is a chronic, relapsing disease of the skin with psychological and somatic impacts that leads to substantial effects on the quality of life. The aim of this study was to determine the quality of life in psoriatic patients.
Methods: This cross-sectional study was conducted on 97 psoriatic patients in dermatology and PUVA clinic in Afzalipour hospital in Kerman from March 2009 to March 2010. Quality of life and disease severity were Dermatology Life Quality Index (DLQI) and Psoriasis Area Severity Index (PASI). Data analysis was done through conducting, chi-square and one-way AVONA tests and P<0.05 was considered as significant.
Results: 55.7% of patients were male and mean age of them was 35.3 years (range: 16-75 years). Psoriasis vulgaris was the most common type (76.3%), and arthropathy was seen in 3.1% of patients. The mean duration of the disease was 21 months (range: 11 months-30 years).The mean of DLQI score was 14.1(range: 1-29) and mean PASI score was 18.6 (range: 0.6-66.6). DLOI score correlated with severity of disease (PASI), marital status, and type of the disease (P<0.05).
Conclusion: Psoriasis has a severe negative impact on the quality of life of the patients. Therefore, supportive social and spiritual efforts are necessary to decrease these effects.
Akram Ansar, Vali-O-Allah Hosseinpoor, Abbas Zamanian, Mahmood Farshchian,
Volume 3, Issue 1 (3-2012)
Abstract
Background and Aim: C-reactive protein (CRP) is an inflammatory biomarker and its level increases in serum of psoriatic patients. Its level is also associated with Psoriasis Area and Severity Index (PASI) score.Methods: CRP serum levels in patients with psoriasis were measured before and after treatment with narrow-band ultraviolet B (NB-UVB) and the data were analyzed in relation the PASI score improvement.
Results: Baseline CRP levels among psoriatic patients were higher than normal. These levels decreased significantly after treatment. At the beginning of the study, patients with higher levels of CRP also had more extensive and severe skin involvement. Highest decrease in CRP was observed in patients who responded better to the treatment and acheived higher PASI 75%. There was an association between baseline PASI scores and CRP levels.
Conclusion: Patients with moderate to severe plaque-type psoriasis had systemic inflammation too, which was demonstrated by having higher levels of CRP. Skin disease activity also was associated with higher levels of CRP. Phototherapy healed the psoriatic skin lesions and also reduced inflammation and decreased CRP levels.
Mahmood Farshchian, Elaheh Soltanie, Leila Moosavee, Hossein Mahjoob, Abbas Zamanian, Haleh Nazerian, ,
Volume 3, Issue 2 (6-2012)
Abstract
Background and Aim: Psoriasis is a chronic inflammatory
dermatosis that affects 0.6% to 4.8% of the general population. Our aim was to compare the effect of narrow band UVB
(NB-UVB) on normal flora of cutaneous plaques and normal skin in psoriatic
patients.
Methods: Twenty
psoriatic patients without any contraindication of phototherapy were enrolled
in this study. Samples from psoriatic lesions and adjacent normal skin, before
and after phototherapy with NB-UVB were taken. Patients were treated with
NB-UVB three times weekly until complete remission. Finally, quantity of normal
cutaneous flora on normal and involved skin, before and after treatment was compared.
Results: The mean±SD of
the NB-UVB sessions and the mean cumulative dose were 26.35±4.95 and 2.05±0.57 J/cm2, respectively. The number of Staphylococcus epidermidis, S. aureus and diphtheroids on psoriatic plaques reduced after phototherapy.
Conclusuion:
The quantity of normal cutaneous flora on normal skin is less than psoriatic plaques,
and it reduced on normal and involved skin after phototherapy.
Zahra Hallaji, Maryam Akhyani, Vahide Lajevardi, Mayade Raeiati Damavandi,
Volume 3, Issue 3 (9-2012)
Abstract
Background and Aim: Psoriasis is a chronic papulosquamous
disorder, which affects about 2% of the population. Psoriasis is relatively
common in childhood: more than 10% of cases start before the age of 10. Tha aim
of this study was to compare the clinical characteristics between pediatric-onset
and adult-onset psoriasis in Iranian patients.
Methods: In 2006 and 2007, clinical data were collected
from all patients with psoriasis diagnosis referred to Razi Hospital. They were
categorized into two groups: pediatric-onset psoriasis patients and adult-onset
psoriasis patients. Clinical variables such as number of patients, gender, age
of onset, family history, and stress as a precipitating factor, the first site
of involvement, clinical type and involved sites were compared between the two
group.
Results: From total of 162 patients, 50 patients (33.2%)
were considered as pediatric-onset group. The percentage of males in the
pediatric-onset group was 48% compared with 58.9% in the adult-onset group. In
the pediatric-onset group positive family history was 20% and in the
adult-onset group was 12.5%. Stress as a precipitating factor was nearly the
same in both groups. Plaque type psoriasis was the most common clinical
presentation and the head and neck was the most common site of involvement in
both groups.
Conclusion: Our findings, similar to previous studies
showed that the involvement of female gender, family history and the onset of
psoriasis on the scalp in children were more than adults.
Nafiseh Esmaeili, Amirhooshang Ehsani, Mehdi Mohseni-Badalabadi, Kambiz Kamyab, Abbas Karimi,
Volume 3, Issue 4 (12-2012)
Abstract
Background an Aim: parapsoriasis is a rare chronic
idiopathic dermatosis which commonly manifests with round or oval scaling and
itching erythematosus plaques on trunk and extremities. Considering the size of
the lesions, parapsoriasis is divided into two groups: small plaque and large
plaque. Study of demographic characteristics of this disease may help to
identify the high risk groups who are more susceptible to cutaneous lymphoma
with high mortality as well as proper allocation of health service resources.
Methods: In this retrospective cross-sectional study,
affected parapsoriasis patients whom were referred to Razi Hospital in Tehran between
April 2003 to March 2009 were studied. Three hundred and twenty patients were
investigated for variables: age, sex, place of residence, location of the lesions
and clinical subgroups according to the histopathology reports.
Results: 53.4% of patients were female. The disease was most
commonly observed in age group of 20 to 50 years and the mean age of the patients
was 43.3 years. Eighty-five percent of the patients were inhabitant of Tehran
province. 88.1% of patients had large plaque lesions and 11.9% had small plaque
lesions. The most common sites of lesions were on the trunk (53.4%) followed
by the extremities (38.7%).
Conclusion: Based on these findings, it was determined that
parapsoriasis most commonly affects middle-aged women. Involvement of trunks and
extremities were most commonly observed. Large plaque type was the most common
type.
Mahmoud Farshchian, Akram Ansar, Mohammad Reza Sobhan, Saadat Torabian,
Volume 4, Issue 1 (3-2013)
Abstract
Background and Aim: Psoriasis is a common chronic inflammatory skin disease. The risk factors of metabolic syndrome have been reported with greater frequency in patients with psoriasis. In this study, we aimed to evaluate these risk factors and compare them with normal population, as the control group.
Methods: In this case-control study, 55 patients with psoriasis were studied from 2011 to 2012 and 55 matched (for sex and age) persons were considered as control group. Age, gender, body mass index, systolic and diastolic blood pressures, smoking, alcohol consumption, type of disease, and blood levels of triglyceride, total cholesterol, LDL, HDL, and fasting sugar were evaluated in both case and control groups and compared.
Results: Our findings showed that levels of TG (P=0.005,OR: 1.02, 95%CI: 1.0-1.34) and LDL (P=0.03, OR: 1.04, 95%CI: 1.0-1.09), the frequency of smoking (P=0.02, OR: 2.2, 95%CI: 1.1-3.2), and the mean of systolic blood pressure (P=0.004, OR: 1.07, 95%CI: 1.02-1.33) were significantly higher in psoriatic patients, compare with control group.
Conclusion: Higher frequency of hypertension and lipid abnormalities in psoriatic patients may enhance the risk of cardiovascular diseases in them. Therefore, we recommend to check all patients with psoriasis, regardless of their disease severity, for serum lipid profiles and blood pressure. In addition, we strongly recommend giving up smoking, as a part of psoriasis treatment.
Akram Ansar, Leyla Jahangard, Pouyan Pahlevani, Bahman Rasouli, Saadat Torabian, Sahar Rasouli,
Volume 4, Issue 3 (9-2013)
Abstract
Background and Aim: Psoriasis vulgaris is a common chronic
dermatic disease impresses many aspects of patients’ life. Many clinical
researches focus on quality of life recently, to evaluate clinical
interventions and treatments. This study planned to recognize different aspects
of life in patients suffer psoriasis vulgaris.
Methods: This case-control study was performed on 100
patients suffer psoriasis vulgaris in 1391 year and 100 people who didn’t have
any specific disease as control group. Quality of life was measured by standard
quality of life questionnaire (SF-36) and data obtained were analyzed with chi
square and t tests.
Results: Average score of SF-36 in psoriasis patients group
65.05±15.51 was significantly less than control group 78.31±11.93 (P<0.001). Difference between patients and
control group was significant in all of aspects except physical and emotional
aspects (P<0.05).
Conclusion: According to the findings of this study, patients
with psoriasis vulgaris had a significantly lower quality of life, in
comparison with the control group. Therefore, these patients require special
attention and specific planning to improve and manage different aspects of
their lives.
Ahmad Alipour, Zare Hossein, Emadi Seyyed Naser, Abdollahzade Hassan,
Volume 4, Issue 4 (12-2013)
Abstract
Background and Aim: Psoriasis is a chronic disease that causes deformity and disability in patients. There is little information about the impact of psychological interventions upon this disease. The purpose of this study was to evaluate the impact of group cognitive behavioral therapy upon physical factors such as severity and level of disease and extent of itching, and mental health of psoriasis patients.
Methods: This research was conducted as a semi-experimental study using pre-test and post-test with a control group and the follow-up period. Twenty Psoriasis patients were allocated into experimental and control groups. The group cognitive behavioral therapy was administered to 10 psoriasis patients allocated into the experimental group for 12 sessions. The members of both groups filled in the Psoriasis Area Severity Index (PASI) for the assessment of severity of psoriasis, general health questionnaire (GHQ), and the Quality of life in patients with pruritus (ItchyQoL) questionnaires.
Results: The results indicated that the group cognitive-behavioral therapy did not have any impact upon the improvement of physical symptoms (severity and level of disease and extent of itching), but it was effective on improving the patients' psychological status. Cognitive behavioral therapy has improved the patients' general health. There is a significant difference between the two groups in terms of multiple covariance analysis for different aspects of general health, including anxiety and insomnia (effect size 0.45 and P=0.004), depression (effect size: 0.25 and P=0.044), physical symptoms (effect size 0.28 and P=0.033), and social functioning (effect size 0.41 and P=0.003).
Conclusion: Although, based on the results, the group cognitive behavioral therapy does not directly affect reduction of physical symptoms of psoriasis the effectiveness of this method on patients' psychological symptoms is considerable as a mediator in the onset, exacerbation, and relapse of the disease.
Masoud Golpour, Mehrdad Taghipour, Fariborz Azizi, Lotfollah Davoudi,
Volume 5, Issue 3 (10-2014)
Abstract
Psoriasis is a chronic inflammatory disease which may occur in childhood. In many psoriasis cases, the disease develops in individuals younger than 18 years old. Psoriasis in children presents with a variety of clinical manifestations. Becouse of its atypical presentations, early diagnosis of psoriasis is difficult in children. The plaque type psoriasis is the most common form of the disease in children. Different treatments such as phototherapy and systemic therapies have been proposed, but using any of them leads to serious complications in children. Therefore, early diagnosis and proper management of the disease are the main components of the treatment in pediatric psoriasis cases. Herein, we aimed to provide a general overview on the pediatric psoriasis, including its epidemiology, pathogenesis, clinical manifestations as well as the treatment and discussing the latest related information.
Freshteh Osmani, Ebrahim Hajizadeh, Parvin Mansoori,
Volume 6, Issue 1 (4-2015)
Abstract
Background and Aim: Psoriasis is an inflammatory skin disease, which is related to the immune system and is characterized by the rapid growth of skin cells. The aim of this study was to investigate some risk factors in psoriasis and also to check that whether the rate of recurrence is fixed or variable in different seasons by using a time-dependent coefficients rate model.
Methods: After reviewing the files of psoriasis patients that had been hospitalized in March 2011 to March 2014 in the dermatology ward of Imam Khomeini Hospital in Tehran, a total of 160 patients who had relapses leading to hospitalization, entered to the study. A rate model with time dependent coefficients by using R software version 3.1 was fitted and risk factors for recurrence were identified. Effect of the season on the recurrence of psoriasis was evaluated.
Results: Recurrence rate of psoriasis was 7.2 times higher in winters than in springs, which had the lowest recurrence rate. Spring and summer were associoated with lower recurrence rates. Effect of season on the relapse of the disease was significantly different for different seasons (P<0.01). Also, infection, stress, positive family history, hypocalemia, the normal number of white blood cells and temperature changes were associated with psoriasis relapse (P<0.05).
Conclusion: Recurrence rate of psoriasis is different in different seasons. Psoriasis recurrence rate was 7 times higher in winters in comparison with springs.
Zeinab Ghafari, Sahar Pak,
Volume 6, Issue 2 (7-2015)
Abstract
Background and Aim: The aim of this study was to compare the health status and perceived stress in patients with psoriasis and healthy individuals in Shahrekord, Iran.
Methods: In this case-control study, 45 patients with psoriasis and 45 healthy individuals were recruited through convenient sampling. Healthy individuals and patients were matched according to their sex, age and education levels. The instruments of research were SF-36 and perceived stress questionnaires.
Results: This study showed that the mean perceived stress in psoriasis patients (27.0±4.6) was higher than healthy individuals (20.5±12.2) (P=0.001). Mean score of health status in patients was 44.9±7.9 less than its average in normal healthy subjects (62.1±7.5) (P0.001).
Conclusion: Psychological stress may play a role in the exacerbation of psoriasis because of visibility of psoriatic lesions. It is associated with deep effects on the health status of the patients.
Reza Safdari, Alireza Firooz, Hourieh Masourian,
Volume 7, Issue 3 (10-2016)
Abstract
ackground and Aim: Psoriasis is a complex disease with lifelong social and emotional consequences. It also impairs quality of life (QoL) and needs prolonged management. So in addition to suitable treatment, self management strategies are required to improve patient health and QoL. On the other hand, mobile phone applications have changed the interaction of patients with health services. The objective of this study was recognition of informative and educational parameters for the development of an application for self management of psoriasis.
Methods: In this cross-sectional study, 100 psoriatic patients and 26 dermatologists were randomly selected. The investigation. Tool was a questionnaire developed by researchers including demographic and clinical data, education and management of life style, and capabilities of application for self management of psoriasis, which its validity was approved by a group of experts and its reliability was confirmed by test- retest.
Results: The mean scores for importance of demographic and clinical data, education and management of life style, and capabilities of self management application were 80.6%, 85.7%, 88.8% by the patients, and 83.7%, 71%, and 75% by dermatologists, respectively.
Conclusion: The recognition of self management parameters considered important by patients, as those involved directly with the disease, and by dermatologists, as experts in the management of disease, are essential in the efficacy and applicability of self management of psoriasis. Patients who know the benefits and risks of self management programs and have self-confidence are more compliant with treatment programs determined by their physicians, and manage their disease more seriously.
Yousof Fakour, Amir Houshang Ehsani, Saeedeh Mohammadi,
Volume 7, Issue 3 (10-2016)
Abstract
Background and Aim: Psoriasis is a common chronic skin disease with high morbidity and economic burden for patients and healthcare system. The goal of this study was to evaluate the impact of age, disease severity, and therapeutic regimen on the quality of life of the patients with psoriasis who were treated with biological drugs.
Methods: This cross-sectional study was conducted on 110 patients suffering from psoriasis whom were admitted to the psoriasis clinic in Razi Hospital, Tehran, Iran in 2015 and 2016. The Persian version of the Dermatology Life Quality Index (DLQI) questionnaire was used to evaluate patients' quality of lives. Using IBM SPSS Statistics (IBM Corp., Armonk, NY, USA) version 22, descriptive and inferential statistics methods were applied to summarize and present the collected data. Chi square test was used for making comparisons.
Results: Seventy-four male patients and 36 female patients were enrolled. The mean age of the participants was 38.8 (range: 18 to 73) years. DLQI scores had a normal distribution and a mean ± standard deviation (SD) equals to 6.51±6.66. The correlations between age and disease severity, quality of life and age, as well as quality of life and disease severity, and quality of life and treatment were not significant (P>0.05).
Conclusion: It seems that the quality of lives of the patients were not affected by the age, severity of the disease, and therapeutic regimen of biological drugs.
Sadegh Abedi, Mohamad Hasan Davazdah Emamy, Amir Houshang Ehsani, Mehdi Jafari,
Volume 8, Issue 2 (7-2017)
Abstract
Background and Aim: Regarding the relatively high prevalence of depression in people with psoriasis, the present study was conducted to determine the role of type D personality and difficulties in emotion regulation in predicting the symptoms of depression in patients with psoriasis.
Methods: This study was a descriptive correlational study. Among patients referred to the Dermatology Clinic of Razi Hospital in Tehran from November to January 2016, 60 patients with psoriasis were selected using available sampling method. The research instruments included type D Personality Questionnaire (DS-14 scale), Difficulties in Emotion Regulation Scale (DERS), and Beck Depression Inventory (Second Edition) (BDI-II). Finally, the data were analyzed using Pearson correlation coefficient and multiple regression tests.
Results: The results of this study showed that there is a significant positive correlation between type D personality and difficulties in emotion regulation with symptoms of depression in patients with psoriasis (P<0/01). Regression analysis with enter method also showed that the two components of type D personality (negative affect and social inhibition), as well as two subscales (lack of emotional awareness and lack of emotional clarity) in difficulties in emotion regulation scale can predict the symptoms of depression in psoriasis.
Conclusion: Type D personality traits and difficulties in emotion regulation can affect the psychological consequences of psoriasis, including depression in people with this disease.
Kimia Akbari, Farshad Hashemian, Maryam Shie Morteza, Parviz Toosi,
Volume 8, Issue 2 (7-2017)
Abstract
Background and Aim: Psoriasis vulgaris is a chronic skin disease which is treated by many systemic or topical drugs. There is no cure for this disease and patients have to take medicaments for a long time, so having knowledge on adverse effects of current medicaments may prevent them and improve treatment process. The aim of this study was to evaluate the incidence of side effects of non biologic systemic drugs in psoriasis.
Methods: In this observational study, we evaluated 200 hospital charts of patients with moderate to-severe psoriasis referred to dermatology clinics of Shohada and Loghman Hospitals in Tehran in 2016. SPSS statistical tools were used to determine the percentage of adverse events. Chi square was used to show the association of gender-related complications and student T-test to evaluate age-related complications.
Results: %56 of patients were male, %26.5 were 25-34 year-old, with mean age of 42±14.2 years and %83.5 of patients had no family history of psoriasis. 11% of patients were hypertensive. Methotrexate was the most commonly used drug and the most common reported adverse event for it was increasing liver function tests (%6.2 in oral and %21.2 in IM injections). The most common reported adverse event for cyclosporine was increased blood pressure which was seen in 17 patients (15.3%). The most common side effect of acitertin was scaling, observed in 11 (%9.6) of patients. There was no relationship between age and sex of patients and development of side effects.
Conclusion: This study showed systemic treatments for psoriasis can change laboratory biomarkers and cause skin eruptions.
Robabeh Abedini, Vahideh Lajevardi, Maryam Nasimi, Maryam Mashayekhi,
Volume 8, Issue 3 (10-2017)
Abstract
Background and Aim: Psoriasis is a common, chronic and inflammatory skin disease. It has been determined that obesity may be associated with this disease. So, the aim of this study was to determine the relationship between obesity and severity of psoriasis in patients referred to dermatology clinic of Razi Hospital.
Methods: This cross-sectional study was done on 106 patients with plaque type psoriasis who had not received any systemic treatment .The demographic characteristics such as gender, age, BMI, severity of disease (PASI), waist, and waist to hip ratio were recorded.
Results: 42% of the patients had BMI of 25-30 (over weight) and 32% higher than 30 (obese). The mean BMI in women (30.2±5.6) was significantly higher than men (27.6±4.7) (P=0.02). BMI was correlated to disease severity (PASI) , but it was not significant (a=0.143, P=0.114)
Conclusion: Although we did not find any significant correlation between severity of disease and BMI, but the association between severity of disease and high BMI were concluded.
Parviz Molavi, Majid Rostami, Mehriar Nadermohammadi Moghadam, Atrin Khalkhali, Habibeh Salvat,
Volume 9, Issue 3 (10-2018)
Abstract
Background and Aim: Considering the high role of psychological factors in somatic disorders, especially in dermatologic disorders, the prevalence of personality disorders in psoriatic patients was studied.
Methods: Among patients referred to Dermatology Clinic of Imam Khomeini Hospital in Ardabil, 81 patients with psoriasis (case group) and 80 without skin disease (control group) were evaluated. The two groups were matched in terms of age and sex. The severity of psoriasis was determined based on the psoriasis area and severity index (PASI) index as mild, moderate and severe by the dermatologist. The traits and personality disorders were assessed and compared between two groups using MCMI-III questionnaire.
Results: There was a significant difference in depressive, dependent, obsessive and hystrionic personality traits or disorders between two groups. There was a reverse correlation between the severity were more common psoriasis and obsessive and dependent personality disorders, so they among mild and moderate psoriasis patients.
Conclusion: This study emphasized the role of psychological factors in course of psoriasis. Better strategies for prevention and treatment of psoriasis will be achieved by a careful examination of the behavioral, cognitive and emotional patterns of cluster C personality. It is also necessary to provide psychotherapy services to these patients along with drug therapy.
Shokoofeh Bakhshi, Mohammadali Sepahvandi, Simin Gholamrezaei,
Volume 10, Issue 4 (1-2020)
Abstract
Background and Aim: Psoriasis is a chronic skin disease. Emotion regulation difficulty in patients with psoriasis emphasizes the importance of including a broader approach in clinical management of psoriatic patients. The purpose of this study was to evaluate the effectiveness of mindfulness-based stress reduction (MBSR) on cognitive emotion regulation in patients with psoriasis.
Methods: This study was a semi-experimental study with pre-test, post-test and follow-up. The study population included all the patients with psoriasis referred to specialized dermatology clinics in Khorramabad. The patients were first screened using the inclusion and exclusion criteria. Then 24 patients with psoriasis were selected through convenience sampling method and randomly allocated into experimental and control groups. The instrumental of this study was Cognitive Emotion Regulation Questionnaire (Garnefski & Kraaij, 2006). The experimental group received MBSR intervention during eight sessions. Data analysis was done at descriptive and inferential levels using version 23 of SPSS and with normality tests, MANCOVA and ANCOVA.
Results: MBSR increased the scores of adaptive strategies and decreased the scores of maladaptive cognitive emotion regulation strategies in patient with psoriasis and the effect of treatment was stable at the end of follow-up period (P<0.001).
Conclusion: MBSR skills training can be used as an effective intervention to improve cognitive emotion regulation in patients with psoriasis.
Ehsan Zarei, Atefeh Gholamhosseini, Narges Ghandi,
Volume 12, Issue 3 (11-2021)
Abstract
Background and Aim: Psoriasis is a systemic and non-transmissible chronic inflammatory autoimmune skin disease that about 2-3% of Iranians suffer from it. Cost of management and budgeting and planning for the treatment of patients with psoriasis requires accurate information. The present study estimates the direct and indirect costs for one-year treatment of patients admitted in Razi Dermatology Hospital.
Methods: In this descriptive-analytical study, treatment costs of 170 patients with psoriasis, including direct (medical and non-medical) and indirect costs were evaluated by census method and using a researcher-made checklist, from October 2017 to October 2018. The fee was collected through reviewing patients' bills in the hospital information system and through telephone interviews with patients.
Results: The average cost of one year was 9037480 Tomans ($ 758), of which direct cost of treatment was 90.22% (8178681 Tomans) and indirect cost of treatment was 9.78% (858799 Tomans). The highest cost of treatment was related to pharmaceutical services with 5825233 Tomans. Also, the total direct medical cost was equal to 7069890 Tomans, of which 62% was the insurance share and 38% was the patient share. The findings showed that injecting biological drugs and accommodation had a significant effect on the direct cost of treatment. Supplementary insurance and accommodation variables also affect out-of-pocket costs.
Conclusion: Drugs made up most of the costs. The high price of biologics and the low coverage of these drugs by insurance companies have caused many economic problems for these patients. According to the findings of this study, it seems necessary to review the more complete insurance coverage of these drugs as well as the use of charitable assistance to cover part of the cost for treatment.
