Showing 4 results for Side Effects
Navid Bouzari, Carlos Ricotti, Francisco Kerdel,
Volume 1, Issue 1 (3-2010)
Abstract
Toxic epidermal necrolysis (TEN) is a server, life-threatening drug-induced mucocutaneous eruption that rarely affects scalp. There has been limited number of cases of TEN arising in patients receiving radiation therapy plus anticonvulsants.Here, we report a case of TEN secondary to anticonvulsant and radiation therapy. An unusual aspect shared by our patient as well as the other reported cases is that the eruption always begins at the site of recent radiation therapy. In this report, we discuss the possible hypotheses for this phenomenon.
Pouran Layegh, Hesamolddin Saeedian, Mahnaz Banihashemei, Habibollah Esmaeilee, Akram Momenzadeh,
Volume 3, Issue 1 (3-2012)
Abstract
Background and Aim: Oral isotretinoin is the only drug that is effective on almost all factors involved in the pathogenesis of acne. Although several studies have been conducted on side effects of this drug, few studies have been conducted on Iranian patients. The aim of this study was to evaluate common clinical and laboratory side effects of this drug in patients with nodulo-cystic acne in Mashhad, Iran.Methods: One-hundred nodulo-cystic acne patients without previous history of hematologic, renal or hepatic diseases and with negative pregnancy tests (in female patients) were enrolled to this study. Patients were treated with standard regimen of oral isotretinoin with a cumulative dose of 120 mg/kg for a treatment course. Demographic data of each patient and results of baseline laboratory tests including serum lipids profile, liver function tests and cell blood counts were recorded.Laboratory tests and the clinical side effects were assessed every two months.
Results: All patients completed treatment course. The most common side effects were cheilitis (87%), dry skin (71%), various types of dermatitis (37%), epistaxis (21%), arthralgias and myalgias (21%). All side effects were mild and treatment discontinuation was not necessary in any case. Although some changes were observed in serum lipid profiles and liver function tests, but these changes were within normal range.
Conclusion: Treatment with oral isotretinoinis associated with few complications in patients with nodulo-cystic acne, but the possibility of serious side effects should always be considered.
Laleh Vaziri, Saman Ahmad Nasrollahi, Alireza Firooz,
Volume 6, Issue 2 (7-2015)
Abstract
Topical corticosteroids (TCs) are very useful in the treatment of some skin disorders such as eczema and psoriasis. TCs exhibit potent anti-inflammatory and anti-proliferative effects responsible for their efficacy in the treatment of skin disorders. TCs can be classified into different groups according to their potency that depends on the intrinsic activity of the corticosteroid molecule, the characteristics of the vehicle (cream, ointment, lotion) that directly influence patient’s compliance and may modify penetration through the skin. British National Formulary classified them into four potency groups with Class I grouping the most potent molecules (e.g. clobetasol propionate) and Class IV the least potent (e.g. hydrocortisone). In contrast, the American classification considers seven potency groups, with super potent, potent, upper mid-strength, mid-strength, lower mid-strength, mild and least potent.
Hatam Ahmadi, Arina Nikkhah,
Volume 14, Issue 1 (5-2023)
Abstract
The human face is the main source of information transmission for many non-verbal messages, including the emotional state of a person. Botox or botulinum toxin is a neurotoxin produced by the bacterium Clostridium botulinum that grows and reproduces in canned foods. There are 8 serotypes of this toxin, the B type is mainly used clinically to treat a wide range of disorders and diseases, and the A type is used for cosmetic purposes. Repeated injections of Botox are necessary to maintain its therapeutic effects. Botox injection in the muscles located under the wrinkles of the face causes them to relax and as a result the skin of that part becomes smooth. Botox injection in therapeutic or cosmetic cases is relatively safe and can be an alternative method to the use of drugs or surgery. Although the frequency of serious side effects for the use of Botox in medical cases is much higher than in cases of cosmetic use. However, the use of Botox in beauty may also have side effects that can be avoided by following different techniques.
