Masoud Golpour, Mehrdad Taghipour, Fariborz Azizi, Lotfollah Davoudi,
Volume 5, Issue 3 (10-2014)
Abstract
Psoriasis is a chronic inflammatory disease which may occur in childhood. In many psoriasis cases, the disease develops in individuals younger than 18 years old. Psoriasis in children presents with a variety of clinical manifestations. Becouse of its atypical presentations, early diagnosis of psoriasis is difficult in children. The plaque type psoriasis is the most common form of the disease in children. Different treatments such as phototherapy and systemic therapies have been proposed, but using any of them leads to serious complications in children. Therefore, early diagnosis and proper management of the disease are the main components of the treatment in pediatric psoriasis cases. Herein, we aimed to provide a general overview on the pediatric psoriasis, including its epidemiology, pathogenesis, clinical manifestations as well as the treatment and discussing the latest related information.
Shahin Hamzelou, Fatemeh Jafari, Maryam Nasimi,
Volume 15, Issue 4 (2-2025)
Abstract
Background and aim: In the severe cases psoriasis, there is a need for biologic treatments which target the immunological responses contributing to the disease pathophysiology. There is no study in definite indications for the treatment choice and the time to start the biologic treatment in Iranian psoriasis patients.
Methods: We designed a cross-sectional study and evaluated all psoriasis patients who had received biologic treatment. After determining the patients who were eligible to participate in the study, their records were studied and analyzed.
Results: 50 patients with the mean age of 42.86 (SD=14.33) participated in the study. Twenty-five patients had received phototherapy for the treatment of psoriasis. All patients had received topical agents and 47 (94%) had received systemic treatment. Adalimumab was the most common biologic treatment used for the treatment of psoriasis patients (74%). 24% of patients had received Infliximab and 4% had received Etanercept.
Conclusion: 50 patients with the mean age of 42.86 (SD=14.33) participated in the study. Twenty-five patients had received phototherapy for the treatment of psoriasis. All patients had received topical agents and 47 (94%) had received systemic treatment. Adalimumab was the most common biologic treatment used for the treatment of psoriasis patients (74%). 24% of patients had received Infliximab and 4% had received Etanercept.
