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Shahin Hamzelou, Fatemeh Jafari, Maryam Nasimi,
Volume 15, Issue 4 (2-2025)
Abstract

Background and aim: In the severe cases psoriasis, there is a need for biologic treatments which target the immunological responses contributing to the disease pathophysiology. There is no study in definite indications for the treatment choice and the time to start the biologic treatment in Iranian psoriasis patients.
Methods: We designed a cross-sectional study and evaluated all psoriasis patients who had received biologic treatment. After determining the patients who were eligible to participate in the study, their records were studied and analyzed.
Results: 50 patients with the mean age of 42.86 (SD=14.33) participated in the study. Twenty-five patients had received phototherapy for the treatment of psoriasis. All patients had received topical agents and 47 (94%) had received systemic treatment. Adalimumab was the most common biologic treatment used for the treatment of psoriasis patients (74%). 24% of patients had received Infliximab and 4% had received Etanercept.
Conclusion: 50 patients with the mean age of 42.86 (SD=14.33) participated in the study. Twenty-five patients had received phototherapy for the treatment of psoriasis. All patients had received topical agents and 47 (94%) had received systemic treatment. Adalimumab was the most common biologic treatment used for the treatment of psoriasis patients (74%). 24% of patients had received Infliximab and 4% had received Etanercept.

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