Journal of

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Background and Aim: Wart is one of the most common viral diseases of skin caused by human papilloma virus (HPV) and results in high costs for therapeutic, cosmetic and hygienic interventions. Euphorbia is an annual plant belonging to Euphorbiaceae family that has seventy species. All of them have latexes with high medicinal values. These plants have anti-viral and anti-tumor substances and 10 species of them are used in traditional medicine for treatment of ulcers, tumors, warts, and other diseases. In this study, the therapeutic effect of Euphorbia macrolada latex on common warts is compared with the standard keratolytic treatment. Methods: The latex of E. macrolada was prepared from Dehgolan region in Kurdistan Province and used directly. The standard keratolytic solution, which contained 16.7 g salicylic acid, 16.7 g lactic acid and up to 100 g collodion was prepared and delivered by the Hamedan Behzisti Pharmacy. A double-blind trial was conducted in Farshchian Hospital, Hamedan, Iran on 88 patients (44 in each group). They were instructed to apply the solutions on their warts twice daily for maximum of 8 weeks. Results: All lesions in both groups were cured after 8 weeks. The meanstandard deviation (SD) of time to cure was 4.51.4 weeks in E. macrolada group and 5.11.6 weeks in the control group. None of these differences were statistically significant (P>0.05). No adverse effects was observed in any of patients. Conclusion: The findings indicated that E. macrolada had a therapeutic effect on common warts. Based on the results of this study, latex of this plant can be used as a complementary or alternative medicine in the treatment of patients with common warts.

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Background and Aim: Warts are benign tumors caused by different types of human papillomavirus. Different methods are used in the treatment of warts. The aim of this study was to compare the effectiveness, side effects and number of treatment sessions of CO₂ laser and cryotherapy in the treatment of plantar warts

Methods: Seventy patients (140 feet) with plantar warts on both feet who referred to the dermatology clinic of Farshchian (Sina) Hospital in Hamadan during 2019-2020 were selected by convenience sampling method. The warts were randomly treated with either CO₂ laser or cryotherapy on each foot. After treatment, patients were evaluated every two weeks for up to five sessions for requirement of treatment repetitions and assessment the extent of healing. In the cases with
non-healing lesion, treatment was repeated once every two weeks for up to five sessions. 

Results: The mean age of the patients was 22.11±8.73 years, and 35.7% were male and 64.3% were female. In the CO₂ laser and cryotherapy groups, the frequency of recovery rate was 81.4% and 41.4%, (P<0.001), and the mean number of treatment sessions was 1.90±0.84 and 3.55±0.69 (P<0.001) respectively. Frequency and type of side effects in the CO₂ laser and cryotrapy group was pain 25.7% and 94.3% (P<0.001), itching zero and 32.9% (P<0.001), blisters 2.9% and 82.9% (P<0.001) and hyperpigmentation with zero and 12.9% (P=0.003), respectively.

Conclusion: CO₂ laser is more effective than cryotherapy in less number of sessions and with less side effects for the treatment of plantar warts

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Background and Aim: Genital wart disease is an infectious disease caused by a type of human papilloma virus that is transmitted through direct contact with the skin of people and mainly as a result of sexual intercourse. Therefore, the profile of psychological vulnerability in people with genital warts and its role in the level of impulsivity It was studied in patients at Razi Hospital.
 

Methods: The current research was of a descriptive-correlation type. The statistical population of the research consisted of all the people referred to Razi Hospital who were suffering from genital warts. 122 people were selected and included in the study. Psychological vulnerability questionnaire and Barat impulsivity questionnaire were used in this research. Data analysis was done with analysis of variance and independent t test, Pearson correlation and stepwise regression and SPSS 18 software.
 

Results: The results showed that psychological vulnerability is normal in people with genital warts. Psychological vulnerability plays a role in impulsivity. Paranoid thoughts have an effect coefficient of 0.3030 and a prediction of 0.30.
 

Conclusion: Considering the role of psychological vulnerability in the formation of behavioral disorders such as impulsivity on the one hand and the role of impulsivity in contracting genital warts on the other hand, this research has practical implications in highlighting the areas of prevention and treatment of impulsivity.