Sh. Jafari , N. ebrahimi-E- Daryani , S. Zeinali, M. motalleb Nejad ,
Volume 14, Issue 2 (9 2001)
Abstract
Helicobacter pylori infection causes gastric and duodenal ulcer. However recurrence of infection after eradication would suggest the existence of other reinfecting sources in the gastrointestinal tract (Gl). The aim of this study was to assess the existence ofhelicobacter pylori in dental plaques of patients harboring Helicobacter pylori in their GI tract. Antral biopsies were taken from 40 patients with Gl problems and cultured. Samples were also taken from dental plaques of patients with positive Helicobacter pylori culture under microaerophilic conditions and evaluated by polymerase chain reaction (PCR) reamplification. The mean age of patients was 40 years 24 (60%) male and 16 (40%) female. The results obtained from dental plaque cultures, which analysed by PCR were all negative, however 7 (17.5%) cases were found positive by PCR reamplification. The results showed that Helicobacter pylori could exist in dental plaque and PCR reamplification could be used for its detection as a more sensitive technique. More research should be conducted to examine any relation between the existence of Helicobacter pylori in dental plaques and recurrent GI disorders.
