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The effect of bovine demineralized bone matrix on regeneration of rabbit parietal bone defects
S. Aghazadeh , Hr. Azimi Leysar , M. Ashouri , Mj. Kharazifard ,
Volume 23, Issue 2 (23 2010)
Abstract

Background and Aims: The present study was designed for evaluation of bovine demineralized bone matrix (DBM) in healing process of bone defects and comparison of bovine DBM (xenograft) and human DBM (allograft) which is used clinically.

Materials and Methods: Seven male white New Zealand rabbits were used in this study. The incision was made directly over the midsagital suture of the parietal bone. Then 3 bicortical defects were created with trephine bur No.8 (8mm diameter). The defects were randomly filled with graft materials. One of the defects was left without any graft in all samples (as a control defect). The amount of bone formation was evaluated 3 months after surgery histopathologically. The data were analyzed using Friedman test, and when P-value was less than 0.05, the pair wise group comparison were performed by Wilcoxon (Boneferroni adjusted) test.

Results: Statistical analysis showed that there was a significant difference between bovine DBM group with control group (P=0.03). Furthermore, human DBM group was significantly different from control group (P=0.02). However, the difference between bovine DBM group and human DBM group was not statistically significant (P=0.87).

Conclusion: The results of this study showed the satisfactory bone healing in rabbit parietal bone defects filled with bovine DBM. The amount of healing in these defects was similar to bone defects which were filled with human DBM that is used clinically.


Comparison of anxiety and pain in dental treatment of children by syringe with toy shape needle cover and conventional syringe
Majid Mehran, Roza Haghgoo, Mohsen Ashourioun, Elham Seifali, Nasrin Takzaree,
Volume 32, Issue 2 (10-2019)
Abstract
Background and Aims: Most children get a lot of anxiety while they visit a dentist. The most important factor in the child's fear at the beginning of treatment is the syringe and needle. Ways to cope with this anxiety include behavioural control techniques such as mental regeneration, distraction, and induction. The purpose of this study was to compare the pain and anxiety in children when using a syringe and toy- shape syringe needle. This study was the first study that used a toy-shape needle cover.
Materials and Methods: This clinical trial study was conducted on 20 children age from 5 to 8 years. More than half of them were anxious with Cfss-Ds (Dental Subscale of the Children's Fear Survey Schedule) and FIS
(Facial Image Scale) anxiety diagnostic tests, and the rest of them were not anxious. Patients were randomly divided into two groups. The first group received local anesthesia with conventional syringe and the second group, by syringe with toy shape needle cover. Following, the first group received local anesthesia by syringe with toy shape needle cover, and the second group, by a conventional syringe. Heart rate measuring and pain evaluating test was performed. Analysis of heart rate and anxiety data was performed by non-parametric wilcoxonsianed Ranks T-test (P-value was considered significant at 0.001).
Results: The mean amount of pain measured after using a syringe with a toy shape needle cover and using conventional syringe had a significant difference of 5.20% between the two groups. The pain was reduced in children who received local anesthesia by syringe with toy shape needle cover (P<0.001).
Conclusion: The physical appearance of the injection device plays an important role in reducing the anxiety and pain of injection in the children.

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