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Showing 6 results for Azam

M. Mirzaie, A. Kavosi, A. Atbaie, F Moazami, Sh. Nooribaiat,
Volume 24, Issue 3 (21 2011)
Abstract

Background and Aims: Non-steroidal anti-inflammatory drugs (NSAIDs) are the most common drugs prescribed for controlling and post root canal treatment pain. During the last decade, a new generation of NSAIDs has been introduced such as Celecoxib and Gelofen with less gastrointestinal side effects and more analgesic effect. No studies have been performed to compare Celecoxib and Gelofen with other NSAIDs considering the reduction of post-endodontic pain therefore, this study was designed.
Materials and Methods: In this randomized double blind clinical trial study, 90 patients were divided into 3 groups and underwent root canal therapy. Celecoxib, Gelofen, or placebo was randomized prescribed to the patients 1 hour before treatment. The intensity of pain was recorded using visual analog scale (VAS) at 4, 8, 12, 24, 48 hours after completion of root canal treatment. The data were analyzed by means of repeated measurements, multiple comparisons and one-way ANOVA tests using SPSS software. P<0.05 was considered as the level of significance.
Results: The results showed significant difference between Celecoxib and Gelofen in comparison with placebo at 8 and 12 hours after initiation of treatment. There was no significant difference among three groups at 4, 24, and 48 hours after initiation of treatment.
Conclusion: According to the results, use of Gelofen or Celecoxib before treatment reduces post-endodontic pain. These drugs can be prescribed before initiation of treatment as the effective agents for reduction of post-endodontic pain


Rabbani Khorasgani Mohammad , Aliasghari Azam , Maryam Khoroushi,
Volume 28, Issue 2 (7-2015)
Abstract

  Dental caries is a multi-factorial disease and the most common human infection that annually are spent millions dollars to control and treat it. Several methods have been proposed so far to control it. The most important control methods it is now include : dental hygiene, proper nutrition , fluoride therapy , the use of non- cariogenic sweeteners . Also, the use of probiotics , nanomaterials , bacteriophages , antimicrobial peptides and anti- caries vaccines can be considered as new perspective of human in the dental caries control field. In addition, the use of complementary and alternative therapies , especially herbal drug therapy recently has been considered . Demonstrating the efficacy of complementary medicine against dental caries and its use in combination with conventional medicine or trial of new methods for decline of dental caries in the future would be hopeful.


Fateme Ramezanalizadeh, Azam Aliasghari, Mohammad Rabbani Khorasgani, Maryam Khoroushi, Arezoo Tahmourethpour, Ahmad Reza Jabbari,
Volume 29, Issue 4 (1-2017)
Abstract

Background and Aims: Dental caries is the most common infectious diseases. Among the oral bacteria, Streptococcus mutans and Streptococcus sobrinus are considered as the main causes of tooth decay. The aim of this study was to evaluate the production of hyperimmune bovine colostrum containing specific antibodies against cariogenic bacteria and its antimicrobial effects on the growth and adhesion of Streptococcus mutans and Streptococcus sobrinus in the laboratory.

Materials and Methods: In this experimental study, three pregnant bovine immunized with killed antigens of strains of Streptococcus mutans, Streptococcus mutans with Streptococcus Sobrinus and Streptococcus sobrinus through intramuscular injections. After delivery, The colostrum samples were collected, and the changes of anti-streptococci antibodies titers in colostrum and serum were determined by agglutination. Also,their antimicrobial effects against the growth and adhesion of oral streptococci were surveyed by the microtiter plate method. Data were analysed by One-Wey ANOVA in SPSS software.

Results: The results showed that in hyperimmunized bovine , the antibodies titers against injected bacteria were from 1.1000 to 1.3000 in sera samples and from 1.320 to 1.1280 in whey of colostrum samples. Colostrum of hyperimmune cows reduced the attachment of Streptococcus mutans and Streptococcus Sobrinus about 69 and 43 percents, respectively and also, the low dilutions of it reduced bacterial growth.

Conclusion:  According to the antibacterial effect immune colostrum on two strains of cariogenic bacteria in vitro, It appears that this material could be useful in the prevention and control of dental caries.


Maryam Khoroushi, Mohammad Rabbani Khorasgani, Azam Aliasghari,
Volume 30, Issue 1 (6-2017)
Abstract

Background and Aims: Tooth decay has high prevalence in the world. The use of plant material for the prevention and treatment of this disease for various reasons is considered, due to the increasing resistance of bacteria to antibiotics, the high cost and adverse effects of some chemicals used in dentistry. This study was aimed to determine the antimicrobial effect of alcoholic extract of Pepper (Capsicum annuum) and eggplant skin and cap on the cariogenic streptococci.

Materials and Methods: In this study, the antimicrobial activity of ethanol extract of Capsicum annuum and eggplant skin and cap on the cariogenic streptococci, including Streptococcus mutans, Streptococcus sobrinus, and Streptococcus sanguis by microtitre plate method for MIC (Minimum Inhibitor Concentration) was performed. Data were analyzed by one-way analysis of variance using Prism 5 Graph Pad software.

Results: MIC for the Capsicum annuum and eggplant skin for Streptococcus mutans was 250 mg/ml (SD=0.052), and for the Streptococcus sobrinus and Streptococcus sanguis was 125 mg/ml (SD=0.027). The MIC for the cap eggplant for Streptococcus mutans and Streptococcus sobrinus was 500 mg/ml (SD=0) and for S. sanguis was getting 125 mg/ml (SD=0.159).

Conclusion: This study showed that the herbal extracts of Capsicum annuum and eggplant skin and cap had beneficially antimicrobial effects on all three strains of cariogenic streptococci.


Zainab Kadkhoda, Sahar Rafiei Chokami, Azam Hosseini,
Volume 30, Issue 1 (6-2017)
Abstract

Background and Aims: Cervical tooth hypersensitivity (CTH) is defined as a sharp pain of short term that occurs in dentin exposed to the oral environment. The aim of this study was to evaluate the efficacy of a desensitizing toothpaste containing potassium nitrate (Sensodyne®) for relieving of CTH, when used locally or as tooth paste.

Materials and Methods: 36 patients were enrolled in this study. They were randomly divided into three groups I) Tooth brushing without toothpaste, II) Local application of toothpaste containing potassium nitrate 5%, III) Tooth brushing with toothpaste containing potassium nitrate 5%. Assessment of CTH was done by evaporative (using air and water spray) and cold stimuli at baseline, 1, 3, and six weeks after the treatment. To compare pain changes over time, due to the interaction between the variables of the studied groups and time, one-way ANOVA was used at any time. Due to the difference of variance between groups to compare pairs of groups, Dunnett T3 test was used.

Results: During the study period, no adverse event observed. In all three groups, pain decreased gradually. Local application of toothpaste had the most favorable effect on CTH. Therefore, when compared with that of the first group, the percentage reduction in pain were statistically significant (P=0.03).

Conclusion: Local application of toothpaste containing potassium nitrate as a desensitizing ingredient is a better choice for treatment of CTH than that of application with toothbrush.


Azam Ahmadian Yazdi, Samareh Mortazavi, Hosein Saeedi Moghaddam,
Volume 32, Issue 3 (11-2019)
Abstract

Background and Aims: Dental diagnosis may be affected by the occurrence of the errors in the intra-oral radiographic images and the patients’ treatment plan can be problematic in these cases. The repetition of these radiographs increases the risks of radiation exposure for the patients in turn. The present study assessed the incidences of common periapical radiographic errors taken by dental students in oral and maxillofacial radiology department of Mashhad dental school in 2017.
Materials and Methods: In this cross-sectional descriptive study, 1470 periapical radiographs prepared by student during a semester of 2017 were collected and evaluated. Radiographic observations were done and the incidence of conventional radiographic errors were determined. Finally, the frequency and percentage of radiographic errors were determined based on the type of radiography sex, the age of the patient, and the history of radiography. Then, results were analyzed using the Chi-Square test and SPSS19 (P=0.05).
Results: Film placement (27.2%), cone-cut (27.2%), elongation (13.2%) and horizontal angle (10.9%) were reported as the most common radiographic errors. The repetition rate of the radiographs was 2.9%; among them, the highest errors were Cone-cut errors in the upper jaw
Conclusion: Based on the results of this study, the most radiographic errors included film position and Cone-cut errors and these two errors were the most frequent cause of repetitive radiographies that required the provision of specific training for the prevention of these errors.


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