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Showing 3 results for Dehghani

A. Eskandarlo, R. Bardal, M. Dehghani,
Volume 24, Issue 1 (23 2011)
Abstract

Background and Aims: Cone beam computed tomography (CBCT) produces high-quality data about diagnosis and periodontal treatment. To date, there is not enough research regarding periodontal bone measurement using CBCT. The aim of this study was to compare the accuracy of CBCT in measuring periodontal defects to that of intraoral radiography and probing methods.
Materials and Methods: Two-hundred and eighteen artificial osseous defects (buccal and lingual infrabony, interproximal, horizontal, crater, dehiscence and fenestration defects) were created on 13 mandibles of dry skulls. The mandibles were put into a plexiglass box full of water to simulate soft tissue. CBCT images, radiographic images taken with parallel technique and direct measurements using a WHO periodontal probe were recorded and compared to a standard reference (digital caliper). Inter and intra observe consistencies were assessed using Intra class correlation coefficient and pearson correlation.
Results: Inter and intra observer consistencies were high for CBCT and probing methods (ICC- Intra class correlation coefficient>88%), but moderate for intraoral radiography (ICC-Intra class correlation coefficient > 54%). There were not any significant differences between observers for all techniques (P>0/05). According to paired T-test analysis, mean difference for CBCT technique (0.01 mm) was lower than that for probing (0.04 mm) and radiography (0.62 mm). CBCT was able to measure all kinds of lesions, but radiography could not measure defects in the buccal and lingual sites.
Conclusion: All three modalities are useful for identifying periodontal defects. Compared to probing and radiography, the CBCT technique has the most accuracy in measuring periodontal defects.


Mahdi Tabrizizadeh, Hengame Zandi, Maryam Kazemipoor, Fatemeh Mokhtari, Abbas Dehghani,
Volume 25, Issue 3 (1 2012)
Abstract

Background and Aims: Calcium hydroxide has a pronounced antimicrobial activity against most of the bacterial species found in infected root canals and endodontic infections. It is one of the most frequently used intracanal medications in endodontic therapy. The objective of this study was to determine the antimicrobial efficacy of six calcium hydroxide formulations (mixed with saline, lidocaine 2%, chlorhexidine 2%, chlorhexidine 0.2%, Iodine Potassium iodide (IKI) 2%, and glycerin) on Enterococcus faecalis using agar diffusion test.
Materials and Methods: Twelve culture plates were incubated with Enterococcus faecalis. Five cavities were made in each plate with 5 mm diameter and 4 mm depth. Two plates were randomly considered for each calcium hydroxide formulation and filled completely with creamy mixture of tested materials. The plates were incubated at 37ºC for 48 hours. The diameter of inhibition zone around each well was recorded in millimetres and data were submitted to ANOVA and Tukey tests.
Results: The results of this study showed that all tested calcium hydroxide pastes had good antimicrobial activity. The antimicrobial activity of calcium hydroxide mixed with lidocaine, chlorhexidine 2% and IKI 2% were significantly greater than that of calcium hydroxide mixed with saline (P<0.001). No significant differences in the antimicrobial  were found between the other groups (P>0.01).
Conclusion: Considering the results of this study, lidocaine 2%, chlorhexidine 2% and IKI 2% are suggested to be used for preparation of calcium hydroxide paste. Further studies with different methods are needed for confirming these results.


Ali Dehghani Nazhvani, Mahboobeh Razmkhah, Amirreza Jassbi, Mohammadreza Khademalizadeh, Afsoon Mahmoodi,
Volume 32, Issue 4 (1-2020)
Abstract


Background and Aims: Oral squamous cell carcinoma (OSCC) is one of the most prevalent oral cancers with increased risk in individuals younger than 40 years especially in developed countries. There are many evidences that people who have plenty of fruits and vegetables in their diets tend to have lower risk of cancer. In this study, we evaluated the anticancer effect of four medicinal plants of Otostegia Persica, Otostegia Michauxii, Otostegia Aucheri, and Hibiscus Sabdariffa on OSCC cell lines.
Materials and Methods: In this study, methanolic & dichloromethane extracts of the above medicinal plants were used in order to evaluate their effect on oral squamous cell carcinoma cell line in different concentrations and after 24 , 48 and 72 hrs by MTT assay test. Finally, the appropriate concentration for repeating the test were chosen.
Results: In this study, the mean amounts of IC50 for O. persica and O. Aucheri were less than the two other herbs and the least and most amount of IC50 were related to the dicloromethanolic extract of O. persica after 72 hrs and the water extract of H. sabdariffa after 24 hrs, respectively.
Conclusion: It was concluded that all of the plants evaluated especially O.Persica and O.Aucheri had anticancer properties and dichloromethalonic extracts of these plant were more effective than that of methanolic extract.


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