Showing 10 results for Eshghyar
N. Eshghyar , N. Taghva Gasemiyan ,
Volume 9, Issue 2 (9 1996)
Abstract
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AR-SA Intrabony neurofibroma is a very rare lesion
(6% of all types of neurofibroma) and in 80% of cases it is seen in spine.
Current study is aimed to analyze the published articles in this field as well
as presenting a rare case.
N. Eshghyar , M. Ashori ,
Volume 10, Issue 1 (8 1997)
Abstract
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EN-US
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AR-SA Adenomatoid
odontogenic tumor is a benign nonprevalent epithelial odontogenic tumor that
induces odontogenic ectomesenchyme. The nature of AOT have always been
questionable. In current study, as well as evaluating the prevalence of AOT cases
in pathology department of Tehran university dental schools, some majorclinical
features (gender, age, location, relation with aimpacted tooth) and
histopathological features ( cyst wall relation, calcified mass or amyloid like
fibrils) were thoroughly evaluated.
N. Eshghyar , N. Kafie ,
Volume 11, Issue 3 (8 1998)
Abstract
In this study we try to clear the prevalance of age and sex and clinical and radiographic manifestations of primary hyperparathyroidism. In this duration 47 patients with primary hyperparathyroidism that bed in two important hospitals in Tehran were studied.The ratio between women to men was 7 to 1 and most prevalance of disease were in fouyth decade. The pain boon was the cheif complain of patients and osteopenia was the most radiographic findings.In addition a case of primary hyperparathyroidism with mandibular and other bone involvement was reported.
N. Eshghyar , A. Eilanlo ,
Volume 12, Issue 3 (10 1999)
Abstract
The aim of this retrospective statistical study was to determine the prevalcence and frequency of age and sex distributions of pemphigus disease. Pemphigus disease classified as autoimmune bullous dermatoses which is a chronic mucocutaneous disease.This study was performed in Razi Hospital and department of oral pathology of dental school, Tehran University of Medical Sciences. The most frequently effected area was buccal moucosa of oral cavity. The most rate of recurrence was found in oral cavity which being more common in middle age females (25-44 years).
N. Eshghyar , M. Bateby ,
Volume 14, Issue 2 (9 2001)
Abstract
Different methods can be used to treat the malignant disease surgery, radiotherapy, chemotherapy, and even cryotherapy are different approach to reach the best treatment for patients. The aim of this cross sectional study was to evaluate the prevalence of oral side effects followed by chemotherapy of cancerous patients in Imam Khomeini hospital. This study was conducted on 80 patients who were under chemotherapy more than once and their oral lesions were evaluated considering their physical conditions. Mucositis was the common problem (66.2%) and the most involvement area was observed in tongue (55%). High percentage of this lesion in adult and senile might be due to deficiency in their immune system.
M. Eslami , N. Eshghyar , F. Tirgari , G. Rezvani ,
Volume 17, Issue 1 (7 2004)
Abstract
Statement of Problem: Differentiation of dentigerous cyst from unicystic ameloblastoma, discovering any initial ameloblastic changes in lining epithelium of dentigerous cyst at early stage, and differentiation between hyperplastic odontogenic epithelium in fibrous capsule of dentigerous cyst from ameloblastic proliferation, need to an accurate and reliable technique.
Purpose: The aim of this study was to determine and compare Ki-67 immunoreactivity in various locations of the epithelium of Dentigerous cyst and Unicystic Ameloblastoma.
Materials and Methods: In this historical Cohort study, 15 cases of dentigerous cyst and 9 cases of unicystic ameloblastoma were selected. Immunohistochemistry staining was performed by M1B-1 (murine monoclonal antibody against Ki-67). The stained nucleous were counted in basal and suprabasal layer of lining epithelium of both lesions in 3000 epithelial cells. Finally, the percentage of positive cells (presented as labeling index) was calculated, t- student test was used to analyze the related data.
Results: Ki-67 (LI) in basal layer of Dentigerous cyst (2.59±1.66) and Unicystic Ameloblastoma (3.76±79) had no significant differences, but Ki-67 (LI) in suprabasal layer of unicystic ameloblastoma (2.15±0.69) was significantly higher than dentigerous cyst (0.77±0.55) P=0.003).
The difference between the average numbers of positive cells for Ki-67 (LI) in these two lesions was statistically significant (P<0.05) and it was higher in Unicystic Ameloblastoma than Dentigerous cyst.
Conclusion: Based on the findings of this study, it is suggested that Ki-67 (LI) in suprabasal layer or throughout the epithelium can be considered as a useful marker for differential diagnosis between dentigerous cyst and unicystic ameloblastoma.
Ms. Sheykhrezaee , N. Eshghyar , B. Farzaneh , K. Ashofteh Yazdi ,
Volume 17, Issue 3 (7 2004)
Abstract
Statement of Problem: Total removal of tissues and remnant microorganisms as well as canal shaping are the essential objectives of endodontic therapy. A successful endodontic treatment is obtained through Shilder’s principals, however complete observation of this technique using stainless steel files manually is problematic and time-consuming. Modern technology, in order to eliminate such problems, has presented new facilities such as Nickel-Titanium (NiTi) files and engine driven instruments.
Purpose: The aim of this in-vitro study was to compare the canal debridement efficiency of three engine driven instruments: Rotary, Reciprocal and Vertical.
Materials and Methods: In this experimental study, 60 mesial roots of human first and second mandibular molars were divided into three groups randomly. In each sample, one canal was considered as case, the other one as control. Files used in Reciprocal and vertical groups were of handy Ni-Ti type and in rotary group, rotary Ni-Ti files were used. After debridement, the roots were sectioned at 3mm and 5mm from anatomic apex, stained and examined under light microscope. Comparison criteria between case and control groups were based on residual debris and predentin and the level of root canal preparation and shaping after debridement. Data were subjected to kruskal-Wallis non-parametric test.
Results: There was no significant difference between the efficiency of debridement at 3mm and 5mm sections between all groups. But difference in time consumption was significant ranked from the shortest to the longest as rotary, reciprocal and vertical.
Conclusion: The efficiency of debridement between the three automated instruments was approximately equal, however the instrumentation time was different between three groups. Rotary system was the fastest one, as compared with reciprocal (second) and vertical (last). It may be concluded that rotary system has a superiority over the other two groups in conventional root canal therapies.
N. Eshghyar , N. Jalayer Naderi , P. Sarraf ,
Volume 18, Issue 1 (30 2005)
Abstract
Statement of Problem: Odontogenic keratocyst is a developmental odontogenic cyst which arises from dental lamina. One of the important features of odontogenic keratocyst is strong tendency to recurrence.
Purpose: The purpose of this study was the statistical evaluation of age and gender of patient as well as area of involvement in odontogenic keratocysts in the oral and maxillofacial pathology department of dental faculty of Tehran University of Medical Sciences from 1971-2002. Materials and Methods: This study was a cross sectional, descriptive one. Medical records were reviewed and variables such as age, gender and site of involvement were recorded. The data were analyzed with SPSS software.
Results: The relative frequency of odontogenic keratocyst was 36%. 66% of cysts were in men and 34% in women. 68% of lesions affected the lower jaw and 32% the upper jaw. Regarding the site of involvement, 48% of lesions involved the molar region of mandible and 42%, the anterior part of maxilla. The occurrence of keratocysts was higher in this sites. Most of the cases were diagnosed in the third decade.
Conclusion: Based on the findings of this study, odontogenic keratocyst was more prevalent in men, mandible and the third decade. The posterior part of mandible and anterior region of maxilla were involved most frequently.
M. Eslami , N. Eshghyar , F. Ensani , S. Seifi ,
Volume 19, Issue 1 (3 2006)
Abstract
Background and Aim: The hormone receptor status in breast cancer has been pivotal in determining the likelihood of response to hormonal manipulation. Tumors which are both estrogen and progesterone receptor positive are much more likely to respond to anti-hormone therapy than negative tumors. There is well-established similarity between breast tissue and salivary glands. The aim of this study was to evaluate the progesterone receptor expression in pleomorphic adenoma and adenoid cystic carcinoma of salivary glands.
Materials and Methods: In this descriptive study, immunohistochemical staining with progesterone antibody was performed on 14 pleomorphic adenoma (PA) and 15 adenoid cystic carcinoma (ACC) paraffin blocks. The percentage of positive cells was determined using an eye piece graticule. Immunoreactivity was categorized as either positive (reactivity more than 5%) or negative (reactivity less than 5%). In addition the existence of progesterone receptor in tumor cells, stromal cells (fibroblasts), inflammatory cells and salivary glands around tumors was evaluated. Data were analyzed with T and Mann Whitney U tests with p<0.05 as the limit of significance.
Results: Immunohistochemical staining for progesterone receptor was negative in 15 ACC and 13 PA. Only one case of PA showed immunoreactivity for progesterone receptor. Also, 12 normal salivary glands around tumor were positive. Inflammatory cells, endothelial cells and fibroblasts did not show immunoreactivity in most cases.
Conclusion: The results indicate the lack of progesterone receptor expression in ACC and PA of salivary glands.
N. Eshghyar, P. Motahhary, S. Rahrotaban,
Volume 21, Issue 4 (19 2009)
Abstract
Background and Aim: Angiogenesis plays a central role for development and progression of malignant tumors.It is considered as an important factor for predicting of malignant tumor's behavior such as metastasis to lymph nodes and other clinicopathologic factors. However , it is still a controversial factor especially in oral squamous cell carcinoma.The aim of this study was to evaluate the correlation between angiogenesis and clinicopathologic parameters such as presence of metastatic cervical lymph node in the tongue squamous cell carcinoma.
Materials and Methods: In this cross-sectional study, 40 cases of squamous cell carcinoma of the tongue were selected from the archive of cancer institute of Tehran University of Medical Science. Sections were prepared from paraffin blocks and immunohistochemically stained with antibody against CD34. Stained vessels were counted in 4 fields ,the most vascular areas at low magnification, in each areas of intratumoral ,peritumoral and nontumoral adjacent tissue in two groups with metastatic lymphnodes (N+) and without (N-). The average counts from the four most vascular areas were recorded as the mean microvascular density (MVD). Data were analyzed by 3wayANOVA and Independent T- test with p<0.05 as the level of significance.
Results: High mean MVD-CD34 was significantly correlate with positive cervical lymph node metastasis in intra tumoral and peritumoral areas but there was no significant correlation between mean MVD-CD34 and age, gender, and differentiation of tumor.
Conclusion: Based on the results of this study, CD34 can help us to determine the presence of cervical lymph node metastasis and may also determine the outcome of a primary squamous cell carcinoma of the tongue.
