Background and Aims: Guided endodontics is a new technique that is now evolving. It is used in many treatments, especially in access cavity preparation and locating root canals in teeth with pulp canal obliteration (PCO), microsurgical endodontics, and fiber post removal in retreatments. In addition, this technique is independent of operator experience, requires less treatment time for the patient, and is more precise and safer than conventional endodontics. This technique involves the use of cone beam computed tomography imaging (CBCT), tooth surface scanning, and special software to provide guidance for performing endodontic treatment in a fast, safe, and minimally invasive manner. This review article aims to introduce guided endodontics and to describe its technique, advantages, and limitations.