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Showing 3 results for Kharazifard
The effect of bovine demineralized bone matrix on regeneration of rabbit parietal bone defects
S. Aghazadeh , Hr. Azimi Leysar , M. Ashouri , Mj. Kharazifard ,
Volume 23, Issue 2 (23 2010)
Abstract

Background and Aims: The present study was designed for evaluation of bovine demineralized bone matrix (DBM) in healing process of bone defects and comparison of bovine DBM (xenograft) and human DBM (allograft) which is used clinically.

Materials and Methods: Seven male white New Zealand rabbits were used in this study. The incision was made directly over the midsagital suture of the parietal bone. Then 3 bicortical defects were created with trephine bur No.8 (8mm diameter). The defects were randomly filled with graft materials. One of the defects was left without any graft in all samples (as a control defect). The amount of bone formation was evaluated 3 months after surgery histopathologically. The data were analyzed using Friedman test, and when P-value was less than 0.05, the pair wise group comparison were performed by Wilcoxon (Boneferroni adjusted) test.

Results: Statistical analysis showed that there was a significant difference between bovine DBM group with control group (P=0.03). Furthermore, human DBM group was significantly different from control group (P=0.02). However, the difference between bovine DBM group and human DBM group was not statistically significant (P=0.87).

Conclusion: The results of this study showed the satisfactory bone healing in rabbit parietal bone defects filled with bovine DBM. The amount of healing in these defects was similar to bone defects which were filled with human DBM that is used clinically.


Effect of resin and type of surface treatment on the flexural strength of cracked feldspathic porcelain
Kermanshah Hamid , Alhosseini Seyedeh Narges Ameri , Ghabraei Sholeh , Kharazifard Mohammad Javad ,
Volume 28, Issue 1 (5-2015)
Abstract

  Background and Aims: Porcelain restorations are often ground for clinical adjustment and this removes the surface glaze layer and introduces flaws that can grow in wet environments due to stress-corrosion, reduce the strength of porcelain and limit restoration lifetime. The aim of this study was to introduce some surface treatment methods to control the flaws of ceramic restorations external surface and improve their strength.

  Materials and Methods: 40 feldspathic discs were prepared and divided into 4 groups (n=10): not indented (group 1) and others indented by vickers with 29.4 N and received different treatments: no treatment (group 2), polished (group 3) and polished-silane-resin (group 4). Biaxial flexural strength of discs was tested after water storage. Data were analyzed using one-way ANOVA .

  Results: The mean flexural strength of specimens in group 1 (134.49±12.60), 2 (94.81±15.41), 3 (89.20±16.22) and 4 (80.67±12.01) were measured. Group 1 (not indented) revealed significantly higher strength (P<0.001) than that of indented groups (2, 3 and 4) . There was no significant difference between group 2 (no treatment) and 3 or 4 (treated) and between treatment methods (3 and 4) (P=0.136).

  Conclusion: The strength of porcelains is dependent on presence of cracks. With the limitations of this study, none of the treatment methods could strengthen the cracked ceramic.


Interobserver and intraobserver variability in the histopathologic assessment of oral lichen planus based on modified WHO criteria
Fereshteh Baghai Naini, Shiva Gandomi, Pouyan Aminishakib, Nazanin Mahdavi, Monir Moradzadeh, Mohamad Javad Kharazifard, Maedeh Ghorbanpour,
Volume 31, Issue 1 (6-2018)
Abstract
Background and Aims: In 1978 WHO (World health organization) formulated a histopathological definition for diagnosis of OLP (oral lichen planus). Previous studies showed that diagnosis of OLP with these criteria are not reproducible. In 2003 Van der Meij et al. represented new clinical and histopathologic definition for diagnosis of OLP known as modified WHO criteria. The purpose of this study was to evaluate the interobserver and intraobserver variability in the histopathological assessment of OLP based on the modified WHO criteria.
Materials and Methods: Fifty five microscopic slides which OLP and OLL (Oral Lichenoid Lesion) were recognized in their clinical differential diagnosis were given to 6 pathologists in two phases with 3 months interval. Each reviewing pathologist was asked to apply the modified WHO definition of OLP and to categorize each case as either OLP, or compatible with OLP. Then, the interobserver and intraobserver variability were assessed by calculation of repeatability coefficient and Kappa statistics.
Results: The results of this study demonstrated that interobserver variability based on modified WHO criteria was 0.77 (strong), while the intraobserver variability varied from 0.58 (moderate) to 0.82 (strong).
Conclusion: In the present study, the interobserver and intraobserver variability in the histopathologic assessment of OLP based on modified WHO criteria was stronger than previous studies which assessed WHO criteria. However, in order to propose the replacement of WHO criteria with modified WHO criteria, further studies with more cases and comparing the two methods is required.

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