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Showing 5 results for Nazanin
Prevalence of oral lesions in patients with HIV/AIDS in Rasht (Iran)
Maryam Rabiei, Seyed Mahmood Rezvani, Nazanin Asadpour, Ehsan Kazemnejad Leyli,
Volume 27, Issue 3 (9-2014)
Abstract

  Background and Aims: AIDS-associated oral lesions are important, in terms of diagnostic-prognostic role and monitoring patients moreover some of them may reduce patient’s quality of life. The aim of this study was to determine the prevalence of oral lesions in HIV patients.

  Materials and Methods: This descriptive cross-sectional study was carried out among a total of 62 HIV+ patients who attended a counseling and treatment center in Rasht. Demographic information, drugs and laboratory status were extracted from patients’ files. Data were analyzed using univariate and multivariate logistic regressions with multiple linear regressions.

  Results: From 62 cases, 50 were male and 12 female and the mean age was 40.5±11.3 years. 59 patients had oral lesions including periodontal disease (95%). The most prevalent oral lesions included: periodontitis (67.7%), oral candidiasis (41.9%) of erythematous (35.4%) and pseudomembranous types (6.45%) and angular cheilitis (12.9%). Patients with removable denture presented a higher rate of erythematous candidiasis and angular cheilitis (P=0.001). In this study, periodontal diseases were rosed by the post-diagnosis years (P=0.024) and the antiretroviral medications (P=0.002). Patients on the prophylactic medications (P=0.043) were less likely to have erythematous candidiasis age may caused angular cheilitis (P=0.041). Pseudomembranous candidiasis was inversely correlated with CD4 + L levels (P=0.052).

  Conclusion: The majority of the cases in this study were IV drug user males within the 4th decade of life. Although oral lesions were not common, but the dental and periodontal statuses exhibited poor oral hygiene which need more attention.


A review on the oxidative stress in recurrent aphtous stomatitis
Mehryari Mahsa , Mortazavi Nazanin , Sayyadi Fatemeh , Mohsenitavakoli Saman , Zahedpasha Shaghayegh , Mortazaviamiri Seyedhadi , Bijani Ali , Kazemi Hamed Hossein , Motallebnejad Mina ,
Volume 27, Issue 4 (1-2015)
Abstract

  Background and Aims: The purpose of the present study was to review the studies regarding serological and salivary oxidant / antioxidant status in patients with recurrent aphthous stomatitis (RAS).

  Materials and Methods: The literature was searched using key words RAS, Antioxidants, Saliva, Hematinic (s) and Hematinic Acid in the last 10 years, particularly the recent 3 years (2010-2013). At total of 37 clinical trials, 18 case-control articles were selected and evaluated fulfilling the requirements as the RAS patients having at least 3 oral aphthous attack per year. The exclusion criteria included systemic as well as periodontal diseases, iron deficiency associated anemia, medication usage and smoking.

  Conclusion: Almost all lipid-peroxidation studies in serum and saliva were manifested by an increase of malondialdehyde (MDA) concentration in RAS patients compared with controls. This would indicate the role of reactive oxygen species (ROS) in the etiology of the disease. Serum trace elements (Zn, Se) were reduced and Cu was increased in RAS patients in comparison with control individuals. A decreased serum superoxide dismutase (SOD) and an increased salivary SOD were observed in all RAS patients. Catalase (CAT) and uric acid (UA) analyses were non-inclusive. Levels of paraoxonase and arylesterase as well as antioxidant vitamins (A, E, C) were lower in RAS patients than that of controls.


Microleakage of three self-etch bonding agents in class 5 composite cavities
Saeed Nemati Anaraki, Hamed Karkehabadi, Nazanin Zeinab Garshasb Zadeh,
Volume 29, Issue 1 (7-2016)
Abstract

Background and Aims: Microleakage is one of the most common problems in bonding systems, which cause different clinical shortcomings such as post operative sensitivity, marginal discoloration and pulp necrosis that can decrease those using bonding systems. The aim of this study was to compare the microleakage of three self etch bonding agents (generation 6 and 7) in class 5 composite cavities.

Materials and Methods: In this experimental study, 30 facial class 5 cavities were prepared in 30 human premolar teeth which were freshly extracted for orthodontic purposes. Cl V cavities were prepared in 2*3*2 mm dimensions. Occlusal margins were in enamel and gingival ones in cementum and randomly divided into 3 groups of 10 each. Then the cavities were treated by clearhil SE Bond (Kuraray, Japan), G Bond (GC, Japan), and Opti Bond Solo Plus (Kerr, USA), according to the manufacturers’ insductions. Then the cavities were filled using Z100 resin composite. The specimens were then immersed in a 50% AgNo solution for 24 hrs. Then, the teeth were cut buccolingually to be evaluated for dye penetration with stereomicroscope. Data were analyzed using Kruskal-Wallis test.

Results: This study revealed that Opti bond solo plus had type1 microleakage (dye penetration up to 1/3 of cavity) in 80% of specimen, and type 4 microleakage (along axial wall) in 10%. Clearfil SE bond had no leakage in 50%, type1 in 40% and type 2 (up to 2/3 of cavity) in 10%. But there was no significant difference in the microleakage at the gingival margins between 3 groups (P>0.05).

Conclusion: Clearfil SE Bond and G bond could prevent microleakage more effectively than that of Opti Bond Solo Plus on the occlusal margins. However, no difference in the microleakage on the gingival surfaces was found.


Interobserver and intraobserver variability in the histopathologic assessment of oral lichen planus based on modified WHO criteria
Fereshteh Baghai Naini, Shiva Gandomi, Pouyan Aminishakib, Nazanin Mahdavi, Monir Moradzadeh, Mohamad Javad Kharazifard, Maedeh Ghorbanpour,
Volume 31, Issue 1 (6-2018)
Abstract
Background and Aims: In 1978 WHO (World health organization) formulated a histopathological definition for diagnosis of OLP (oral lichen planus). Previous studies showed that diagnosis of OLP with these criteria are not reproducible. In 2003 Van der Meij et al. represented new clinical and histopathologic definition for diagnosis of OLP known as modified WHO criteria. The purpose of this study was to evaluate the interobserver and intraobserver variability in the histopathological assessment of OLP based on the modified WHO criteria.
Materials and Methods: Fifty five microscopic slides which OLP and OLL (Oral Lichenoid Lesion) were recognized in their clinical differential diagnosis were given to 6 pathologists in two phases with 3 months interval. Each reviewing pathologist was asked to apply the modified WHO definition of OLP and to categorize each case as either OLP, or compatible with OLP. Then, the interobserver and intraobserver variability were assessed by calculation of repeatability coefficient and Kappa statistics.
Results: The results of this study demonstrated that interobserver variability based on modified WHO criteria was 0.77 (strong), while the intraobserver variability varied from 0.58 (moderate) to 0.82 (strong).
Conclusion: In the present study, the interobserver and intraobserver variability in the histopathologic assessment of OLP based on modified WHO criteria was stronger than previous studies which assessed WHO criteria. However, in order to propose the replacement of WHO criteria with modified WHO criteria, further studies with more cases and comparing the two methods is required.

Effect of vitamin C on salivary total antioxidant capacity in healthy male smokers
Nazanin Kamyab, Mahmood Sheikh Fathollahi, Azadeh Khaleghi, Zohreh Mordouei,
Volume 32, Issue 3 (11-2019)
Abstract

Background and Aims: Saliva is the first body fluid that is exposed to the free radicals found in cigarette smoke. Antioxidant substances in saliva, such as vitamin C, play an important role in the defense mechanism against free radicals. Therefore, the aim of this study was to examine the effect of vitamin C on the total antioxidant capacity of saliva in smokers.
Materials and Methods: This randomized clinical trial was performed on 60 healthy male smokers who referred to the dental clinic in Rafsanjan in 2017. Individuals were randomly divided into three groups. The first and second groups received 500 and 1000 mg of vitamin C boiling tablets for three weeks. The third group did not receive any vitamin C supplements. The total antioxidant capacity of saliva was measured using an antioxidant kit and an ELISA reader. Data were analyzed using paired t-test, one-way ANOVA, and Duncan's multiple comparisons test.
Results: The results showed that the mean total antioxidant capacity of saliva after the intervention was found statistically significant among groups (P<0.001). However, the mean total antioxidant capacity of saliva did not differ in the groups receiving 500 and 1000 mg of vitamin C (P=0.420).
Conclusion: The results showed that taking vitamin C increased the total antioxidant capacity of saliva in smokers.
 
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