B Seraj , A. Ramyar , R. Ahmadi , S Ghadimi ,
Volume 19, Issue 1 (3 2006)
Abstract
Langerhans cell histiocytosis (LCH) is a rare disease with formation of granulomatous infiltrations consisting of Langerhans cells, histiocytes, lymphocytes and eosinophilic granulocytes. The ethiopathogenesis of the disease has not been fully clarified yet. It can occur as focal or disseminated form - acute or chronic. Oral manifestations may be the first signs. This article reports a case of a 3 year old boy with LCH suffering from severe dental mobility and foul breathe. Radiographically, the lesions appeared as well-defined radiolucent defects in maxilla and mandible. The microscopic findings consisted of sheet like arrangements of histiocytes with a mixture of eosinophils and other inflammatory cells. Biochemical tests were within normal limits.
Amirhosein Rostami, Seyedali Seyedmajidi, Valiollah Arash, Abbas Ramyar, Nima Hedayati Goodarzi, Amirhosein Ghasemi, Reza Faraji,
Volume 39, Issue 0 (3-2026)
Abstract
Background and Aims: Bimaxillary dentoalveolar protrusion (BDP) is a common orthodontic anomaly characterized by protrusive dental arches and lip prominence. Extraction of the first premolars is a frequently employed treatment approach in these patients. However, the effect of this intervention on Bolton ratios-particularly the overall and anterior ratios-remains unclear. This study aimed to evaluate the impact of first premolar extractions on Bolton ratios in patients with BDP.
Materials and Methods: This experimental study was conducted on archived physical models of 34 Class I patients with BDP and functional lip incompetency (>4 mm) accompanied by lip protrusion, available at the Orthodontics Department of School of Dentistry, Babol, in 2024. All patients had a full complement of teeth from the first incisor to the first molar in each quadrant. After digitizing the models, mesiodistal tooth widths and the overall and anterior Bolton ratios were calculated. Digital simulation of first premolar extraction was performed, followed by reassessment of Bolton ratios. Pre- and post-treatment values were statistically compared using paired t-tests in SPSS (significance level set at 0.05).
Results: Among 34 studied casts, 67.6 % belonged to females. The mean overall Bolton ratio decreased significantly from 90.33 ± 2.23% to 87.72 ± 2.39%, and the anterior ratio declined from 78.19 ± 2.96% to 77.85 ± 3.03% (P<0.001). Additionally, 15 patients exhibited residual space post-treatment, primarily in the mandibular arch.
Conclusion: Based on the results of the present study, first premolar extraction significantly reduced both the overall and anterior Bolton ratios in patients with bimaxillary dentoalveolar protrusion. However, the likelihood of residual space—particularly in the lower arch-should be carefully considered during orthodontic treatment planning to ensure long-term stability and success.
