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M. Ashoori , A. Salimian , N. Jalayer Naderi ,
Volume 19, Issue 4 (6 2007)
Abstract

Background and Aim: Microscopic differentiation between well differentiated squamous cell carcinoma and verrucous carcinoma is very difficult. As these lesions have different clinical course and treatment a reliable method to help distinguish between them is necessary. The basement membrane in oral verrucous carcinoma is generally intact whereas in oral squamous cell carcinoma is mostly discontinuous. This structure can be studied by different methods. The aim of this study was to differentiate these lesions with special staining of basement membrane.

Materials and Methods: In this tests evaluation study, a total of 26 cases consisting of 15 oral squamous cell carcinomas and 11 oral verrucous carcinomas were retrieved from Cancer Institute of Imam Khomeini hospital archive of pathology and their paraffin blocks were cut and stained with Periodic Acid Schiff method. Slides were studied with light microscope to evaluate the continuity of basement membrane. Sensitivity and specificity of this method were calculated.

Results: The sensitivity of this method for differentiating oral squamous cell carcinoma from oral verrucous carcinoma was 100% whereas the specificity was 90.9%. Positive predictive value was 93.75% and negative predictive value 100%.

Conclusion: Based on the results of this study, the sensitivity of this test for diagnosis of oral squamous cell carcinoma was high (100%). Further studies are needed to evaluate the use this method for distinguishing oral verrucous carcinoma from oral squamous cell carcinoma.


Sarvin Sarmadi, Behrad Tanbakuchi, Javad Chalipa, Fahimeh Salimi, Mehrdad Panjnoosh,
Volume 31, Issue 1 (6-2018)
Abstract

Background and Aims: Functional therapy locates the mandible in a more anterior and inferior position. Tongue posture and oropharynx space have a considerable relationship with mandibular posture. The aim of the present study was to determine the changes of tongue posture and oropharynx space following treatment with Twin block appliance in adolescent patients with class II division 1 ma1occlusion.
Materials and Methods: Twenty two patients (14 girls mean age:11.5, 8 boys mean age:12.5 years) who were treated with twin-block appliance were enrolled. Cephalograms were used to assess the linear measurements. Graber pattern and McNamara parameter were used to evaluate the tongue posture and oropharynx space, respectively. Data analysis was performed by paired t-test.
Results: The findings of the present study showed a significant increase in anterior position of tongue (P=0.06). Oropharynx space was increased significantly (P<0.001). There was a significant correlation between the decrease of ANB and anteroposterior increase of oropharynx space.
Conclusion: Twin-block appliance caused considerable forward movement of tongue and significant increase of oropharynx space in the sagittal plan.

Razieh Jabbarian, Reza Emrani, Razie Hosseininavaz, Mahnaz Pouresmaeil, Mohammad Mirzaie, Mahsa Esfehani, Nazanin Gholitabar, Yasmina Davari, Aida Salimi,
Volume 39, Issue 0 (3-2026)
Abstract

Background and Aims: Oral health is recognized as an integral component of general health andlike other health aspects, can significantly impact the quality of life of both the individual and their family. Due to their rapid physical and psychological development, children are particularly vulnerable to the adverse consequences of oral health problems. Accordingly, the present study aimed to investigate the impact of children's oral health on family quality of life and the factors influencing this relationship among children under six years old in Qazvin, Iran.
Materials and Methods: This cross-sectional study was conducted on the parents of 80 six-year-old children in Qazvin city in 2022. A convenience sampling method was employed, recruiting participants from among those attending the Dental School of Qazvin University of Medical Sciences. Initially, the child's demographic information (age, gender, birth order, and family socioeconomic status) was collected from the parents. Subsequently, they completed the Family Impact Scale (FIS) questionnaire. This questionnaire assesses the impact of a child's oral and dental problems on the family, utilizing four subscales. Subsequently, questions were asked regarding general health, oral and dental health, dental visits, and the services received. The collected data were then analyzed using descriptive and analytical statistics including variance, Pearson correlation, and T tests.
Results: 80 parents were enrolled in the study of whom 39 had a son and 41 had a daughter. The mean age of the studied children was 4.72±1.06 years, with an age range of 3 years (the youngest being 3 and the oldest 6 years old). Among the dimensions of family quality of life (FIS), the family finances subscale had the highest mean score (0.53 ± 0.68), while the family conflict subscale had the lowest (0.73±0.44). The overall mean score for family quality of life was 0.52±0.6. No statistically significant relationship was found between the outcome variable (oral health-related quality of life) and the independent variable of family economic status (P>0.05). However, a statistically significant relationship was observed with the independent variable of the child's birth order (P=0.002), indicating that the impact of the child's oral health on family quality of life would increase with a higher birth order. Furthermore, a significant relationship was found between the child's age and two subscales of family quality of life: family activity (P=0.03) and family conflict (P=0.006). Specifically, a younger child's age was associated with a greater impact of their oral health on the family's quality of life. There was a significant relationship between the child's general health and oral/dental health from the parents' perspective and the impact of the obtained FIS score (P=0.001 and P=0.04, respectively).
Conclusion: The findings indicated that a child's oral health status could impact the family quality of life, and this impact was associated with the child's age and birth order.


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