Showing 67 results for Iti
M. Sahebi, P. Bostani Amlashi,
Volume 23, Issue 3 (12-2010)
Abstract
Background and Aims: Selecting an appropriate treatment plan is one of the most critical aspects of dental treatments. The purpose of this study was to compare multimedia system and conventional method in patients' selecting prosthetic treatment and the time consumed.
Materials and Methods: 90 patients randomly divided into three groups. Patients in group A, once were instructed using the conventional method of dental office and once multimedia system and time was measured in seconds from the beginning of the instruction till the patient had came to decision. The patients were asked about the satisfaction of the method used for them. In group B, patients were only instructed using the conventional method, whereas they were only exposed to soft ware in group C. The data were analyzed with Paired-T-test (in group A) and T-test and Mann-Whitney test (in groups B and C).
Result: There was a significant difference between multimedia system and conventional method in group A and also between groups B and C (P<0.001). In group A and between groups B and C, patient's satisfaction about multimedia system was better. However, in comparison between groups B and C, multimedia system did not have a significant effect in treatment selection score (P=0.08).
Conclusion: Using multimedia system is recommended due to its high ability in giving answers to a large number of patient's questions as well as in terms of marketing.
H. Bashizadeh Fakhar, A. Abbaszadeh,
Volume 24, Issue 1 (3-2011)
Abstract
Background and Aims: Accurate bone measurements are essential for determining the optimal size and length of proposed implants. The radiologist should be aware of the head position effects on image dimensions in each imaging technique. The purpose of this study was to evaluate the effect of mandibular plane angle on image dimensions in linear tomography.
Materials and Methods: In this in vitro study, the vertical dimensions of linear tomograms taken from 3 dry mandibles in different posteroantenior or mediolateral tilts were compared with actual condition. In order to evaluate the effects of head position in linear tomography, 16 series of images while mandibular plane angle was tilted with 5, 10, 15 and 20 degrees in anterior, posterior, medial, or lateral angulations as well as a series of standard images without any tilt in mandibular position were taken. Vertical distances between the alveolar crest and the superior border of the inferior alveolar canal were measured in posterior mandible and the vertical distances between the alveolar crest and inferior rim were measured in anterior mandible in 12 sites of tomograms. Each bone was then sectioned through the places marked with a radiopaque object. The radiographic values were compared with the real conditions. Repeat measure ANOVA was used to analyze the data.
Results: The findings of this study showed that there was significant statistical difference between standard position and 15º posteroanterior tilt (P<0.001). Also there was significant statistical difference between standard position and 10º lateral tilt (P<0.008), 15º tilt (P<0.001), and 20º upward tilt (P<0.001). In standard mandibular position with no tilt, the mean exact error was the same in all regions (0.22±0.19 mm) except the premolar region which the mean exact error was calculated as 0.44±0.19 mm. The most mean exact error among various postroanterior tilts was seen in 20º lower tilt in the canine region (1±0.88 mm) and for various mediolateral tilts the most exact error was seen in the canine region in 20º upper tilt (2.9±2 mm).
Conclusion: The mean exact errors in various regions and various 5º to 20º posteroanterior and mediolateral mandibular tilts were in the range of acceptable values (≤1 mm) except for the canine region. However, this effect is more considerable in mediolateral tilt compared with posteroanterior tilt, posterior region compared with anterior region, and upper tilt compared with lower tilt.
Jalil Modaresi, Mahdi Dastorani, Fazlolah Soleymani Najafabadi, Fatemeh Ezodini,
Volume 25, Issue 1 (4-2012)
Abstract
Background and Aims: Radiographic examination is a necessary step in diagnosis of horizontal root fracture. The purpose of this study was to determine the sensitivity and specificity of single radiograph for detection of horizontal root fracture.
Materials and Methods: In this analytical-descriptive study, 30 human freshly extracted teeth were used. Using a hammer and clamp, the teeth were divided into two sections accidentally and then sections were attached together by cyanoacrylate glue. Two radiographs were taken with and without a piece of human mandibular bone. Afterward, radiographs were analyzed by three expert dentists using a slide show device.
Results: The diagnostic sensitivity and specificity of single radiograph for detection of horizontal root fracture without bone was 100%, but in radiographs of teeth with bone was 82.7% and 100%, respectively.
Conclusion: Based on the results of this study, in most cases, the horizontal root fractures can be detected by a single periapical radiograph.
Arash Azizi, Samira Shah Siah, Asma Madhani,
Volume 25, Issue 1 (4-2012)
Abstract
Background and Aims: Recurrent aphthous stomatitis (RAS) is the most common oral mucosal inflammatory disease. The frequency of RAS is as much as 20% in the general population. The cause of RAS is not yet fully understood. Antioxidant is a material which has ability to preserve molecules from damage and also can delay the start of it. The aim of this study was to compare saliva level of total antioxidant status (TAS) in RAS patients with that of normal subjects.
Materials and Methods: In this case-control study, 25 patients with aphthous stomatitis were considered as the case group and 25 healthy subjects as control group. The case and control groups were matched by sex and age. Total antioxidant status (TAS) saliva levels were measured in two groups by spectrophotometer. The data were analyzed with independent sample t-test.
Results: The mean and standard deviation of TAS in case group was 1.64±0.64 µmol/L and in control group was 1.49±0.3 µmol/L. There was not significant difference between case and control groups (P=0.464).
Conclusion: Results of this study showed that there was no statistically significant difference between RAS patients and healthy subjects in saliva antioxidant status levels.
Narjes Amiri Tehranizadeh, Nahid Asgarizadeh, Vajihe Kamel,
Volume 25, Issue 2 (4-2012)
Abstract
Background and Aims: Improper feeding is one of the most important etiologic factors in early childhood caries (ECC). In some clinical trials, breast feeding (BF) is mentioned as a causing factor in ECC. Results in this topic are different or even controversial. It is vital that all general advices given out are consistent with general health education messages. The aim of this study was to conduct a systematic review on the relationship between breast feeding and early childhood caries.
Materials and Methods: Articles, guidelines, related books, and specific databases such as SID, PubMed, Scirus, Elsevier, American Association of Pediatric Dentistry (AAPD), American Association of Pediatrics (AAP) and American Dental Association (ADA) were searched for related topics cited since 1990. Early childhood caries definition, breast feeding and other variables such as sample size, study location and study design were analyzed.
Results: According to data analysis, there was a lack of methodological consistency and inconsistent definitions of ECC and BF in the literature making it difficult to draw conclusions. Results about relationship between prolonged BF and ECC were inconclusive. There was a positive relationship between nocturnal BF and ECC. A history of BF did not have any effect on the caries incidence.
Conclusion: Because of the role of breast feeding in children's health, it is important to inform the parents about the possibility of dental caries due to nocturnal breast feeding.
Amir Aliramezani, Mohammad Hosein Salari, Mohammad Reza Pourmand, Zeinab Kadkhoda, Abbas Foroushani, Farzaneh Aminharati, Sedigheh Ghourchian, Zahra Pakbaz, Saeed Eshraghi,
Volume 25, Issue 3 (7-2012)
Abstract
Background and Aims: Periodontitis is one of the most common oral diseases with the various incidence rates in different populations. A number of bacteria are considered as the major etiologic agents of periodontitis. The aim of the present study was to determine the prevalence of periodontopathogen bacteria in patients using both PCR and culture techniques.
Materials and Methods: In this study, one-hundred patients (including 62 females and 38 males with an average age of 49±11.5 years) with adult periodontitis referred to periodontics department of School of Dentistry/Tehran University of Medical Sciences were investigated. The samples were taken and sent immediately to the laboratory for culture and molecular evaluation. The PCR was performed using specific primers and the statistical analysis of data was performed using SPSS statistic software and McNemar test.
Results: The results demonstrated that the total detection rate in culture method was 64%. The rate of Aggregatibacter actinomycetemcomitans (Aa) was 28% which was significantly higher than that of Porphyromonas gingivalis (Pg) (6%) and Prevotella intermedia (Pi) (3%). 27% of cases showed mixed bacterial growth. 65% of patients were positive using molecular method. The rate of Aa (30%) was significantly higher than that of Pg (7%) and Pi (5%). The mixed PCR positive rate containing of Aa, Pg and Pi was (23%).
Conclusion: In this study, it was found that most of the bacteria isolated using culture and molecular methods were Aa, Pg and Pi, respectively. Although the detection frequencies of both techniques were similar, the specificity, sensitivity and bacterial detection speed of the PCR technique is obviously higher. Therefore, the use of molecular techniques is strongly recommended. However, both techniques seem to be suitable for microbiological diagnostics.
Farin Kiani Yazdy, Masoud Golshah, Mahboobeh Razmkhah, Abbas Ghadery,
Volume 26, Issue 2 (5-2013)
Abstract
Background and Aims: Apoptosis or programmed cell death plays an important role in the pathogenesis of many diseases. Previous studies suggest that apoptosis is involved in the pathogenesis of periodontal disease, on the other hand it is also suggested that diabetes mellitus enhances apoptosis of connective tissue cells. Thus, we measured expression of proteins which are relevant to apoptosis in the gingival tissue of diabetic patients with chronic periodontitis in comparison to non diabetic individuals.
Materials and Methods: 25 patients with diabetes and chronic periodontitis and 16 non diabetic controls were included in this study. 4 weeks after scaling and root planning and oral hygiene instructions, periodontal surgery was done and gingival tissues obtained during surgery, were sent to lab to investigate expression of Fas, P53, Bcl-2 and Survivin using real-time PCR technique. Data were analyzed using Mann-Whitney and Chi-squared.
Results: Pro-apoptotic proteins (Fas, P53) were significantly (P<0.05) higher in gingival tissues of diabetics (9.5×10-6, 2.4×10-6, respectively) in comparison to non diabetics (9.4×10-7, 5.6×10-7), whereas the difference in expression of anti-apoptotic proteins (Bcl-2, Survivin) between 2 groups was not significant (9.7×10-8, 3.5×10-7 in comparison to 1.4×10-7, 3.1×10-7, respectively)( P =0.91, P =0.29 respectively).
Conclusion: Apoptosis was increased in gingival connective tissue of diabetic patients with chronic periodontitis in comparison to non diabetic ones. Therefore , intervention in expression or function of pro-apoptotic proteins (Fas, P53) could be a new goal in the treatment of periodontal disease of diabetic patients.
Babak Amoian, Shaghayegh Noori Bayat, Zahra Molana, Ali Akbar Moghaddam Nia, Fariba Asgharpoor,
Volume 27, Issue 1 (4-2014)
Abstract
Background and Aims : Antibiotics are commonly used for controlling the growth of porphyromons gingivalis (P.g) which is one of the most important etiologic factors in the periodontal diseases. Different side effects of synthetics and chemical drugs such as increasing the drug resistancy in the human pathogens have led to study on the herbal antibacterial effect. The aim of this study was to evaluate the antibacterial effect of cinnamon on the growth of porphyromons gingivalis in chronic periodontitis patients with deep pockets.
Materials and Methods: In this experimental study, samples were provided from patients having pockets. After culturing the microorganism and diagnosis of P.g by gram staining and biochemical tests, cinnamon in different concentrations (10, 50, 100, 250, 500, 750 and 1500 mg/ml ) with oil solvent were prepared and placed by disks in the cultures medium. Positive controls were amoxicillin, metronidazole, ciprofloxacin, amikacin and gentamycin . Oil was negative control. Then the plates were incubated for 24 hours in 37 0 C and then non-growth halos by disk diffusion method, MIC (Minimum Inhibitory Concentration) and MBC (Minimum Bactericidal Concentration) were determined. Data were analyzed using One-way ANOVA test.
Results: The results showed that the cinnamon at the concentration of MIC=750 mg/ml had the inhibitory effects of bacteria and at the concentration of MIC=1500 mg/ml had killing effect. However, this antibacterial effect compared with commonly used antibiotics (amoxicillin, metronidazole), was much weaker (P<0.001).
Conclusion: Cinnamon showed an antimicrobial effect on porphyromonas gingivalis in chronic periodontitis patients with deep pockets.
Arami Sakineh , Aghasadeghi Mohamadreza , Tabatabaie Masome Hasani , Darvishpour Hojat , Sheikhzadeh Sedigheh ,
Volume 27, Issue 4 (1-2015)
Abstract
Background and Aims: Hepatitis B is an important infection route in dentistry requiring different disinfectants to prevent its transmission. The aim of this study was to compare the effects of chemical disinfectants (FD366, ISORAPID and 5% sodium hypochlorite 2/100) to remove Hepatitis B infections from the dental surfaces.
Materials and Methods: In this experimental laboratory trial, serum of 10 HBV patients was poured into microtubes, FD366, ISORAPID and hypochlorite disinfectants were added to them. PCR experiments with viral diagnostic kits were used to diagnose the virus genome. Real time PCR was used to evaluate after incubation with the disinfectants. The reductions occurred in the viral load of Hepatitis B were statistically analyzed using Kruskal-wallis and Mann-Whitney U tests .
Results: No significant antiviral efficacy was noted following the application of FD366 and ISORAPID disinfectants (P=0/07). However, hypochlorite showed the most efficacy to disinfect Hepatitis B and a significant difference was found among them (P<0.0001).
Conclusion: Under the study limitations, FD366 and ISORAPID disinfectants did not show adequate efficacy to remove Hepatitis B virus. Hypochlorite was the most effective disinfectant.
Mehryari Mahsa , Mortazavi Nazanin , Sayyadi Fatemeh , Mohsenitavakoli Saman , Zahedpasha Shaghayegh , Mortazaviamiri Seyedhadi , Bijani Ali , Kazemi Hamed Hossein , Motallebnejad Mina ,
Volume 27, Issue 4 (1-2015)
Abstract
Background and Aims: The purpose of the present study was to review the studies regarding serological and salivary oxidant / antioxidant status in patients with recurrent aphthous stomatitis (RAS).
Materials and Methods: The literature was searched using key words RAS, Antioxidants, Saliva, Hematinic (s) and Hematinic Acid in the last 10 years, particularly the recent 3 years (2010-2013). At total of 37 clinical trials, 18 case-control articles were selected and evaluated fulfilling the requirements as the RAS patients having at least 3 oral aphthous attack per year. The exclusion criteria included systemic as well as periodontal diseases, iron deficiency associated anemia, medication usage and smoking.
Conclusion: Almost all lipid-peroxidation studies in serum and saliva were manifested by an increase of malondialdehyde (MDA) concentration in RAS patients compared with controls. This would indicate the role of reactive oxygen species (ROS) in the etiology of the disease. Serum trace elements (Zn, Se) were reduced and Cu was increased in RAS patients in comparison with control individuals. A decreased serum superoxide dismutase (SOD) and an increased salivary SOD were observed in all RAS patients. Catalase (CAT) and uric acid (UA) analyses were non-inclusive. Levels of paraoxonase and arylesterase as well as antioxidant vitamins (A, E, C) were lower in RAS patients than that of controls.
Shamsolmoulouk Najafi, Reza Yazdani, Behzad Salari, Homa Forouhesh Tehrani, Mohammad Javad Kharrazi Fard,
Volume 29, Issue 2 (11-2016)
Abstract
Background and Aims: The aim of this study was to investigate the effects of sodium bicarbonate against candida albicans, the main infectious factor of denture stomatitis, and to compare it with other common anti-candida medications.
Materials and Methods: Three concentrations of Candida albicans (105, 106, 107 CFU/mL) were prepared. Experimental substances were 5% sodium bicarbonate, nystatin, chlorhexidine, and sterile saline (as control). Each of them was added separately to the same amounts of Candida albicans of different concentrations, and sampled at the intervals of 1, 2, 3 and 4 min. Then, the samples were cultured and incubated. The number of formed colonies was counted for each plate. The data were analyzed, using ANOVA and Tukey test.
Results: Sodium bicarbonate showed a noticeable anti-candida effect on the concentrations of 105 and 106 CFU/mL, with almost similar anti-candida effect as nystatin and chlorehexidine(P=0.29, P=0.32). Nystatin was the most effective medication on the concentration of 107 CFU/mL of candida (P=0.03, P=0.01). Sodium bicarbonate and chlorhexidine were less effective in this concentration with no statistically significant difference (P=1.00).
Conclusion: Sodium bicarbonate showed a significant anti-candida effect at low and medium concentrations of Candida albicans, but nystatin was more effective in the higher concentrations.
Zainab Kadkhoda, Sahar Rafiei Chokami, Azam Hosseini,
Volume 30, Issue 1 (6-2017)
Abstract
Background and Aims: Cervical tooth hypersensitivity (CTH) is defined as a sharp pain of short term that occurs in dentin exposed to the oral environment. The aim of this study was to evaluate the efficacy of a desensitizing toothpaste containing potassium nitrate (Sensodyne®) for relieving of CTH, when used locally or as tooth paste.
Materials and Methods: 36 patients were enrolled in this study. They were randomly divided into three groups I) Tooth brushing without toothpaste, II) Local application of toothpaste containing potassium nitrate 5%, III) Tooth brushing with toothpaste containing potassium nitrate 5%. Assessment of CTH was done by evaporative (using air and water spray) and cold stimuli at baseline, 1, 3, and six weeks after the treatment. To compare pain changes over time, due to the interaction between the variables of the studied groups and time, one-way ANOVA was used at any time. Due to the difference of variance between groups to compare pairs of groups, Dunnett T3 test was used.
Results: During the study period, no adverse event observed. In all three groups, pain decreased gradually. Local application of toothpaste had the most favorable effect on CTH. Therefore, when compared with that of the first group, the percentage reduction in pain were statistically significant (P=0.03).
Conclusion: Local application of toothpaste containing potassium nitrate as a desensitizing ingredient is a better choice for treatment of CTH than that of application with toothbrush.
Seyyede Fateme Basri, Rafat Bagheri, Maryam Sadat Tavangar,
Volume 31, Issue 1 (6-2018)
Abstract
Background and Aims: Fracture and color change are among the most common causes of clinical failure of resin composite restorations. Therefore, this study aimed to examine the fracture toughness and color changes of 3 Nano-hybrid resin composites in dry and wet conditions.
Materials and Methods: Three resin composites were studied. A total of 36 rectangular specimens were prepared for each material, randomly divided into 2 groups, and stored at 37°C dry or soaked in distilled water. In each group, the specimens were subdivided into three groups (n=6) and stored for 1, 7, and 60 days. After each time interval, the specimens were tested for the fracture toughness and loaded at a cross-head speed of 0.5mm/min using a universal testing machine. The baseline and final color measurement was recorded for each specimen using a spectrophotometer. The collected data was analyzed using ANOVA and Kruskal-Wallis tests.
Results: After 60 days, the mean value of fracture toughness was lower in the wet condition compared to that of dry condition. However, it was not significantly different except for aura Bulkfil (P=0.001). Color change was significantly different for Tetric Evoceram and aura with a greater value in the wet condition compared to that of dry (P=0.004). The greatest color stability was found for aura and the least for Tetric Evoceram.
Conclusion: In this study, most of the materials stored in a dry condition showed a greater fracture toughness and color change.
Rahelesadat Mirseifi Nejad Naini, Alireza Daneshkazemi, Fahime Shafiee,
Volume 31, Issue 2 (9-2018)
Abstract
Background and Aims: Increased tooth sensitivity is a common dental problem. One of the mechanisms of dentin hypersensitivity treatment is blocking dentinal tubules. The aim of this study was to compare the average closing dentinal tubules affected by carbonated Nano-hydroxyapatite and fluoride toothpaste using scanning electron microscope (SEM).
Materials and Methods: The enamel of gingival buccal crown surfaces of 42 sound maxillary premolars teeth were removed until the dentin surfaces were exposed. The dentine specimens of 3×3 mm were prepared. The specimens were washed by distilled water after etching and randomly divided into 6 groups. 3 groups were interfered with the carbonated nano-hydroxyapatite toothpaste and the other three groups interfered with Colgate toothpaste in 3, 7 and 14 days. The samples were examined by SEM to check the status of dentinal tubules. Then, they were evaluated by two researchers according to the Hulsmann index. Data were analyzed by using SPSS23 software and Kruskal-Wallis statistical test. The significance level of 0.05 was considered.
Results: The amount of dentinal tubules closure by the two toothpastes was significantly different. This difference was higher in the hydroxyapatite toothpaste than fluoride which were (P=0.024, 0.004 and 0.000), respectively. There were no significant differences among the groups in 3,7 and 14 days (P=0.230, 0.069, 0.537).
Conclusion: The toothpaste containing carbonated nano structural hydroxyapatite was more successful in closing dentinal tubules than Colgate toothpaste in short period of time.
Yalda Elham, Neda Moslemi, Hoda Barati,
Volume 31, Issue 4 (1-2019)
Abstract
Background and Aims: Lichen planus is a chronic inflammatory mucocutaneous disease with unknown etiology. One of the most common manifestations of patients with oral lichen planus is gingival involvement in the form of generalized erythematous areas. The aim of this study was to review the articles evaluating the role of plaque control on the gingival manifestations of oral lichen planus.
Materials and Methods: Motor searches of Ovid Medline and EM base databases, PubMed, Google Scholar, and Science Direct were searched for article published between January 1990 and December 2017 using of relevant key words. After reviewing the abstracts of articles, 20 full articles were selected and among them, 7 relevant articles were reviewed in this study.
Conclusion: From the literature, it was concluded that effective plaque control is the main part of lesions treatment and improvement of symptoms and gingival manifestations of oral Lichen planus.
Siavash Valizadeh, Omid Fatahi Valilai, Mahmoud Houshmand, Zahra Vasegh, Alireza Valizadeh,
Volume 31, Issue 4 (1-2019)
Abstract
Background and Aims: One of the important fields of dentistry is surgery for dental implants. In this field, dentistry has developed considerably in recent years amongst other fields of medicine from the perspective of digital device and software application. Surgical guides help dental surgeon for more precise, confident, easier and shorter surgery. Process of producing these tools are full digital and to somehow complex due to the application of many technical devices, software and protocols. To achieve efficiency, all participants in the workflow must be aware of all steps and data requirements for production of guides. This paper investigates the production process of surgical guide comprehensively, and also, encompass all the steps in process with details.
Materials and Methods: This review article was based on searching Google scholar and PupMed databases considering key words: Surgical Guide, Guided surgery, digital dentistry, dental CAD/CAM, Additive manufacturing. More than 90% of the references were in English language and published after year 2010.
Conclusion: Today dentistry uses many digital solutions for dairy workflow and most of these solutions are developed by engineers in various fields of knowledge. Thus, this information is essential for dentists, surgeon, clinician and laboratory technician, etc. for better collaboration and participation. Amongst, advances in surgery of dental implant have been highly significant and patients benefit from better treatment and less inconvenience. In addition, dentists do surgery more precise and easier because of considering all conditions before of surgery. Thus, it is substantial inform of all steps of production process.
Mohadese Baghdadchi, Elham Siasi Torbati, Kumars Amini,
Volume 33, Issue 1 (7-2020)
Abstract
Background and Aims: Periodontitis is one of the most common causes of damage to the gums and retaining structures of the teeth. Matrix protein, a metalloproteinase, is known as intermediate collagenase and the enzyme collagenase fibroblast, which is encoded in humans by the MMP-1 gene. The aim of this study was to investigate 1G/2G polymorphism in the MMP-1 gene and its association with the periodontal disease in the Iranian patients.
Materials and Methods: In this study, 50 patients with periodontal disease and 50 patients were selected as the control group in Kerman city. DNA was extracted from a person's blood sample using a kit. The desired primers were controlled by the NCBI site. Then, with the Tetra arms PCR technique, the desired polymorphism was multiplied. In the next step, the samples were transferred to electrophoresis gel and examined. The results were analyzed with SPSS software using T-test or Squer Chi-(X2).
Results: The percentage of 1G/1G genotype in the patients group was 8% and for the controls group was 0%. The percentage of 2G/2G genotype for the patients group was 24% and for the controls group was 18%. In addition, the 1G/2G genotype frequency was 68% for the patients group, and for the controls group was 82% (P=0.83). The results of Tetra-arms PCR genotyping of the samples were confirmed by sequencing.
Conclusion: The findings indicated that in Iranian patients, MMP-1 -1607 1G/2G (rs1799750) was not significantly associated with periodontal disease. It is recommended to take more samples from different parts of Iran to confirm the results.
Sara Valizadeh, Ladan Ranjbar Omrani, Zohreh Moradi,
Volume 33, Issue 2 (8-2020)
Abstract
Background and Aims: Enoxolon is a natural licorice and its formula is similar to cortisone. The aim of this double blind randomized match control clinical trial, was to analyze the effect of Arthrodont toothpaste containing 1% Enoxolone on dental plaque, gingival inflammation, and bleeding indices.
Materials and Methods: 40 patients who had gingivitis were selected. They were instructed to brush their teeth twice daily for three minutes then massage the gums with pastes for one minute and then wash their mouths. The patients were divided into two groups: The Arthrodont toothpaste containing Enoxolon, was given to the study group and the Crest toothpaste free of Enoxolon, was given to the control group. At the beginning of the study and after 21 days, plaque, gingival, and bleeding indices were measured. The statistical analyses were done by Paird T test, T test and nonparametrical analysis of Wilcoxon and Mann-Whitney.
Results: In both groups, the three indices decreased significantly. Comparing between the two groups, the gingival and bleeding indices had significantly decreased in the study group (Arthrodont toothpaste) compared to the control group (Crest toothpaste). However, no significance difference in the plaque index between the two groups was found (P=0.143).
Conclusion: The results of this clinical study showed that Enoxolon had anti-inflammatory effect on gingivitis.
Mohsen Sharif Zadeh Ardakani, Ali Mohammad Salari, Mahmod Nasre-Esfahani,
Volume 33, Issue 3 (10-2020)
Abstract
Background and Aims: With increasing age and inability to maintain good oral hygiene, the chances of tooth loss increase and the need for dental implants will increase in the future. It also increases the risk of developing peripheral implants, especially at older ages in the failure of implant treatments. Recently, the high prevalence of cardiovascular disease and peri-implantitis in the elderly has been reported. The aim of this study was to investigate the effect of cardiovascular disease on the peri-implantitis in people with failed dental implants.
Materials and Methods: In this retrospective study, the files of patients referred to Shahid Montazeri Dental Clinic from 2009 to 2018 whose their failed implants were extracted, were collected. There were a total of 793 people with failed dental implants. The variables of this study were demographic information including age and sex, health status in terms of cardiovascular disease and peri-implantitis, which were identified and then statistically analyzed by examining the files of patients with these two variables. Data were statistically analyzed by SPSS25 statistical software and Chi-square was used to determine the effective variables.
Results: A total of 793 patients had failed dental implants, including 368 women (46.4%) and 425 men (53.6%) with an average age of 50.79 years. 42 patients (5.3%) had heart disease and 44 (5.5%) had peri-implantitis. According to the Chi-squared test, the significance level was less than 0.05 (P=0.011).
Conclusion: The results of this study showed that the cardiovascular disease and peri-implantitis were significantly related.
Elahm Siasi Torbati, Nafiseh Tavakkoli, Kumars Amini,
Volume 33, Issue 4 (1-2021)
Abstract
Background and Aims: Periodontitis is an inflammatory multifactorial disease in oral tissues and many genetic reasons and environmental factors responsible. Vitamin D deficiency has been determined to be related to periodontal disease. This aim of this study was to investigate the association between rs7975232 polymorphism in vitamin D Receptor gene and periodontitis in 100 patients (as patient and control groups).
Materials and Methods: Blood samples from 50 patients and 50 control groups were selected and DNA from the samples was extracted by the DNA extraction kit. Genotyping was used by Tetra Arms-PCR method. The use of sequencing was confirmed by the Tetra Arms-PCR genotyping results. Then, statistical analysis was performed using SPSS statistics 20 software and T-test.
Results: Frequency of AA, AC, and CC Genotypes were 25 (50%), 14 (28%), and 11 (22%) in patients’ cases, and 26 (52%), 16 (32%) and 8 (16%) in controls, respectively. AA genotype was the highest genotype between the patient and control groups. Statistical analysis showed no significant association between this type of polymorphism and periodontitis disease in the studied samples (P=0.67).
Conclusion: This finding showed there was not significant association between rs7975232 polymorphism in vitamin D Receptor gene and periodontitis disease in the studied samples. To confirm the results of this study, further studies with large sample size and different types of population are recommended.
