Search published articles


Showing 23 results for Sadegh
Evaluation of anaerobic pathogens in periodontitis patients and its relationship with TGF-1β genomic polymorphism by Tetra Arms-PCR method
Noushin Khandan Dezfuli, Majid Sadeghpour, Mojgan Sarabi Nobakht, Elham Estabarghi, Kumarss Amini,
Volume 34, Issue 0 (5-2021)
Abstract
Background and Aims: Periodontitis is a common and inflammatory infectious disease that causes damage to the tissues supporting the tooth and consequent tooth loss. Periodontal disease is a multimicrobial and multifactorial disease and important anaerobic bacteria are involved in periodontal infection. TGF-1β is one of the growth factors and anti-inflammatory cytokines that play a crucial role in the repair of periodontal lesions. The aim of this study was to evaluate Tetra Arms-PCR with high sensitivity and specificity, which can be used to evaluate the genomic polymorphism among oral samples and show the relationship between TGF-1β and periodontal disease.
Materials and Methods: The present study was a case-control study in the periodontology department of Kerman Dental School. Sampling was done from 100 samples including 50 healthy individuals and 50 patients with microbial periodontal infection. Genotype was analyzed using DNA extracted from the blood of patients by PCR -ARMs-Tetra to determine the relationship between TGF-1β genomic polymorphism and periodontitis. Statistical analysis was performed with SPSS19 software and one-way ANOVA.
Results: The samples were culture positive, therefore, more than 65% of the isolated bacteria were anaerobic which included: Prevotella, Porphyromonas, Fusobacterium, Peptostreptococcus anaerobic. The results of Tetra PCR ARMs after sequence frequency were genotype CC allele (25%), CT allele (20%), TT allele (5%). Percentage of control group were CC allele (20%), CT allele (24%), and TT allele (6%). The frequency of C and T alleles in the patient group was 70% and 30%, and in the control group 63% and 37%, respectively with no significant difference between two groups (P=0.83).
Conclusion: According to the results of this study and the application of anaerobic conditions, forced anaerobic bacteria can be isolated from clinical specimens of oral infections and by Tetra Arms-PCR no significant relationship between TGF-1β genomic polymorphism and periodontitis was observed. In addition, therer was no significant difference in the frequency of alleles and genotypes between the control and patient groups.

Investigating the relationship between stress and oral health-related behaviors changes in final year of high school students prior to university entrance exam
Mostafa Motallebi, Maryam Sadeghipour, Nika Mehrnia, Mohammad Behnaz, Nahid Mohammadnia,
Volume 35, Issue 0 (5-2022)
Abstract
Background and Aims: Today, academic stress and subsequent test anxiety is one of the most important problems for the last year of high school students. In addition to systemic effects, stress can affect the level of oral health by disrupting oral health behaviors. The aim of this study was to investigate the relationship between stress and variables related to oral health in the final year of high school students prior to University entrance exam.
Materials and Methods: In this descriptive-analytical study, the level of stress and variables related to oral health in 180 students of the final year of high school in Tehran, in three time periods during the academic year 2018-2019, were measured by a questionnaire and one clinical examination. Data were analyzed by Friedman, Bonferroni and Generalized Estimating Equations using SPSS software.
Results: As the exam approaches, some variables related to the oral health, such as toothbrush usage pattern, daily sleep, fast food frequency, and sweet snack consumption, changed (P<0.05). Daily sleep changes were significantly associated with the stress changes (P=0.022). According to the results of the Repeated Measures Analysis, significant changes were observed between the average score of the "Cognitive Error" aspect of three times (P<0.001). Also, according to the results of the Bonferroni Test, significant changes related to the difference in the average score of "cognitive error" 6 months and 3 months before the entrance exam (P<0.001), 6 months and 1 month before the entrance exam (P<0.001), and 3 months and 1 month before the entrance exam (P<0.001) were observed. In all three cases, as the time of the entrance exam approaches, the score of "cognitive error" had decreased significantly. Considering that the lower score in this index indicates a higher level of test anxiety, the closer we get to the entrance exam, the higher the level of test anxiety in the "cognitive error" dimension
Conclusion: The academic stress of the national university entrance exam can affect some oral health variables such as daily sleep, however, it is not related to other variables.

Investigating the effect of peer friendship group on the oral health of 9 and 12 year-old students in Qazvin city in 1397- 1398
Seyyed Peyman Shariatpanahi, Pouya Jamshidi, Maryam Sadeghipour Roudsari, Mohammad Hosein Khoshnevisan, Mahshid Namdari, Baharan Arshadi Fard, Sarvin Soleimanpoor,
Volume 37, Issue 0 (3-2024)
Abstract
Background and Aims: Nowadays, the requirement of any policy-making at the national and regional level is to know the level of knowledge of people about oral health and ways to prevent dental caries.  This study examined the habits, actions and economic level of elementary school students in Qazvin city in 2017-2018.  Also, the effects of peer group social network on behaviors related to oral health and obesity was investigated in order to find the way for interventions making it more effective in this social group.
Materials and Methods: In this descriptive-analytical study, 145 students participated. They were in the 3nd and 6th grades of elementary school in the academic year of 2017-2018. The questionnaire used in this study had 20 questions and 4 main sections. The main parts of this questionnaire included demographic characteristics, behavior and habits related to oral health, oral health knowledge of students and families, and socio-economic status. Data were collected through clinical examinations and through valid questionnaires and evaluated using SPSS and Excel software.
Results: According to the results of Pearson's correlation analysis, a significant correlation was observed between the health knowledge scores of individuals and their friends between both groups of casual and close friends (P<0.01). The correlation between the knowledge of individuals and close friends was significantly stronger (P<0.01). Also, there was a significant relationship between socio-economic status and behaviors related to oral health (P<0.05). There was also a significant positive relationship between the number of times close friends brushing their teeth in a social network (P<0.001). This connection was not observed in the friends’ network.
Conclusion: This study determined that close friends can be effective in determining the oral hygiene behaviors of elementary school students.

Page 2 from 2     

© 2024 , Tehran University of Medical Sciences, CC BY-NC 4.0

Designed & Developed by: Yektaweb