Journal of Dental Medicine

Background and Aims: Due to the review of general dental courses, it was necessary to assess the students' satisfaction with this curriculum. The aim of this study was the assessment level of students’satisfaction with the new educational curriculum of the Ministry of Health at the department of restorative dentistry of Tehran university of medical sciences in 2019-2020.
Materials and Methods: In this descriptive cross-sectional trial,72 sixth year dental students of Tehran University who passed the restorative dentistry courses based on the new curriculum were studied. A questionnaire was developed and for validity content assessment, it was presented to 5 professors and then revised. For reliability approval of the questionnaire, test-retest approach was used. The questionnaire was given to the 30 students of the main pilot group in one session and two-week later and agreement percentage and Kappa index were calculated.  After conducting the "test" process and re-testing, the "questions" were statistically analyzed using STATA software.
Results: The most level of satisfaction regarding to practicality of subjects was found for fundamental of restorative dentistry including principles of amalgam class I cavity preparations and restorations on the dentic (81.94% and 76.39% acceptable respectively) and the principles of amalgam classII cavity restorations on the dentic (72.22%). The least satisfaction levels were obsereved in the first and second theoretical restorative courses including tooth-colored restorations (47.22%), onlays and inlays (47.22%) and tooth-colored classII cavity preparations and restorations (48.61%). The amount (P-value or error of the first type) was reported in all questions>0.001.
Conclusion: Despite the limitation of this study, final-year dental students’ satisfaction of theoretical restorative dentistry courses was medium, while it was high for the fundamental and practical restorative courses of 2017 educational curriculum.

Background and Aims: Cathepsin-D is a well-known protease that promotes invasion in tumoral lesions. Considering the cystic neoplasm nature of odontogenic keratocyst (OKC), the aim of this study was to compare the expression of cathepsin-D in this lesion with the unicystic ameloblastoma (UA) and orthokeratinized odontogenic cyst (OOC) for better understanding of its behavior.
Materials and Methods: In this descriptive-analytical study, we used paraffin blocks available in the archives of oral and maxillofacial pathology department of dental school (8 unicystic ameloblastoma (UA), 8 odontogenic keratocyst (OKC) and 8 orthokeratinized odontogenic cysts (OOC)) which they were stained immunohistochemically with cathepsin-D. Then, the samples were observed simultaneously by two oral pathologists for detection the intensity and pattern of epithelial and stromal cells staining. Data were analyzed by SPSS20 and Kruskal-Wallis, Mann-Whitney and Chi-square test (P<0.05).
Results: The staining intensity of the epithelial cells of UA group was significantly more than OOC and OKC (P=0.02). The staining intensity of the stromal cells of UA was more than the other two groups, although this difference was not statistically significant (P=0.32). The pattern of cell staining in epithelium and stroma did not show any significant difference between the three groups in this study (P=0.15, 0.22).
Conclusion: The results of this study regarding the intensity expression of cathepsin-D in these three odontogenic lesions could be considered as a probable evidence for the new odontogenic lesions classification (WHO2017) in terms of reintroducing OKC as an odontogenic cyst. If this idea is rejected, it seems that cathepsin-D expression is not associated with the invasive behavior of this cyst, and further investigation of other markers in the epithelium and stroma simultaneously is suggested for a better understanding of its biological nature.

Background and Aims: Selecting the appropriate education evaluation method and the effects of this choice according to different fields of medical sciences, is one of the current priorities of medical education. Therefore, the aim of this study was to design a checklist for evaluating the practical skills of dental students and to get compared with the global ranking method.
Materials and Methods: A checklist was developed for the assessment of clinical skills of the practical pediatric course according to an action research method. 32 students were evaluated by the checklist method and 32 students were evaluated by the conventional global rating method (sampling was based on available sample).  Faculty staff and students’ satisfaction regarding the two methods were reported by a 6-scaled measure and statistically analyzed by Wilcoxon Signed Ranks test. The students' scores by the two methods were subjected to paired t test for comparison.
Results: The students were more satisfied with the checklist method (P=0.003). The faculty staff considered a greater ability of the checklist method to differentiate between the students (P=0.03). However, in terms of ease of use and suitability, most faculty staff preferred the traditional method (P=0.02). In other cases, there were no significant differences in the views of students and faculty staff towards the two methods.
Conclusion: In the present study, both Checklist and global rating methods were valuable for evaluation, although due to the greater satisfaction of students and faculty staff with the developed checklist method, the possibility of identifying the weak points leading to decreased scores and better assessment of capabilities, this checklist can be used for evaluation instead.

Background and Aims: According to the importance of primary stability on dental implant success and osseointegration, we intend to check and compare the stability and crestal bone loss rate between osteotomy technique and conventional implant insertion techniques.
Materials and Methods: In this study, 26 implants in anterior segment of maxilla in 13 patients were evaluated. The implants were TBR system (Toulouse, France) with 3.5 diameter and 10.5-12 mm length. The implant stability level was recorded immediately after surgery and 3 months later with Ostell mentor. The periapical radiography was taken immediately after surgery, 3 and 6 months to assess crestal bone resorption. Paired t-test and Wilcoxon signed Rank test used for data analysis.
Results: There were no statistically differences between the two treatments techniques in terms of stability (P>0.05). The mean crestal resorption was higher for the osteotomy technique 3 months after implant insertion (P<0.001) but there were no significant differences after 6 months (P=0.678).
Conclusion: Within the limitations of the current study, it can be concluded that the osteotomy it can be considered as a treatment technique in insufficient bone width.

Background and Aims: The aim of this study was to investigate the tooth discoloration caused by cold ceramic compared to MTA Angelus in contact with the washing solutions such as sodium hypochlorite (NaOCl) and normal saline.
Materials and Methods: 50 samples of extracted human maxillary anterior teeth were selected. After preparing the access cavity, they were divided into 4 experimental groups and 1 control group (10 in each group). The access cavities of teeth in groups 2 and 4 were rinsed with 5.25% sodium hypochlorite and those in groups 1 and 3 were rinsed with normal saline. Then, after drying, 3 mm thickness of cold ceramic (groups 1 and 2) and MTA Angelus (groups 3 and 4) were placed in the access cavities of the teeth. After setting of the materials, all specimens were restored with a resin modified glass ionomer. Based on the CIE Lab system, each sample’s total color change (∆E) was obtained before, one, and 90 days after application. Data were statistically analyzed using the Wilcoxon test.
Results: According to the results, there was no statistically significant difference in the average tooth discoloration between the groups filled with cold ceramic and in different time periods (P>0.05). While, in the groups filled with MTA Angelus, the difference in the average tooth discoloration in 90 days after application was significantly higher than one day (P<0.05).
Conclusion: The results of this study showed that compared to MTA Angelus, cold ceramic causes less tooth discoloration over time and therefore, it can be suggested as a more suitable alternative endodontic cement than MTA Angelus.

Background and Aims: Pulp necrosis in immature teeth disrupts root development and makes the teeth susceptible to fracture. Regenerative endodontics is a relatively new modality of treatment where the necrotic pulp is replaced with newly formed healthy tissue which has normal functionality. Many clinical reports have demonstrated the potential of this strategy to induce root maturation and apical closure. However, clinical outcomes are patient-dependent and unpredictable. Developing predictable protocols can be achieved through the interplay of three basic elements of tissue engineering, namely, scaffolds, stem cells, and signaling molecules. Furthermore, the clinical success of this treatment is influenced by both the method of preparing the inner space of the root and the type of biomaterial utilized in the coronal part. In this review, we discuss recent advances in tissue engineering-based strategies for regeneration of the pulp/dentine complex along with their advantages and limitations. 

Background and Aims: Journal of Dental Research is among the dentistry journal with the highest impact factor. This study aimed to map the most important topics for journal editors and readers.
Materials and Methods: The world's active research topics in the field of dentistry related to the Journal of Dental Research in the last 5 years were extracted from SciMapper's SciTrends. Also, we clustered the most cited papers in that journal to show the most important research topics for the journal editors and readers.
Results: We identified and mapped 11 active international research areas in the field of dentistry and related to this journal. Among 146 faculty members of the school of dentistry, 12 had at least one article related to the most active research areas in the journal. In this regard, they had similar articles elated to the 7 clusters out of 13, but their articles are mainly related to the clusters 7 and 19. Among the investigated faculty members, nine had directly collaborated with 21 authors of the mapped clusters. Moreover, 12 faculty members could also connect to the 126 authors with articles in that journal through their scientific collaborators.
Conclusion: One way to publish in a top international journal is to know the most active and interesting research areas for the journal editors and readers. About 8% of the school of dentistry faculty members at Tehran University of Medical Sciences had some research related to the Journal of Dental Research.

Background and Aims: The foundations of a successful root canal treatment are adequate adaptation of the gutta-percha to the canal wall and the establishment of an impermeable apical seal. Despite the common use of M3 and Neoniti rotary files by dentists, no study has been conducted to examine the compliance of gutta-percha in curved canals prepared with M3 and Neoniti files using CBCT. The present study was designed and compiled with the aim of investigating the adaptation of gutta-percha in curved canals prepared with M3 and Neoniti files by CBCT.
Materials and Methods: This randomized controlled laboratory study was conducted ex vivo on 30 permanent human first molar teeth. The teeth were randomly divided into two groups (the first group with M3 and the second group with neoniti), after finding and fixing the appropriate canal path with the examined rotary files. All groups were filled with Single Cone method using F2 gutta-percha and AH26 sealer. Then, the gutta adaptation was assessed using clinical criteria (visual and radiographic) and after the specimens were evaluated using CBCT. All the images obtained from CBCT were converted into the JPEG format and then entered into image J software. The gap between the canal walls and gutta was measured in each canal, and the obtained data were analyzed using the Mann–Whitney U test.
Results: The results showed that the average and standard deviation of gap in M3 files (0.181 ± 0.089) was higher than that of Neoniti file (0.173 ± 0.033). However, no significant difference in the gutta-percha adaptation in curved canals prepared between the M3 and Neoniti files  was observed (P>0.05).
Conclusion: Considering the acceptable adaptation of gutta-percha in canals prepared with M3 and Neoniti files, the use of these two files is recommended in curved canals.

Background and Aims: Educational planning is one of the main areas of education and training, which plays an essential role in the optimal training of human resources. The aim of this study was to compare the educational program (curriculum) of general dentistry in Iran with that of several prestigious dental schools in the Middle East countries.
Materials and Methods: This is a descriptive comparative study using the dental education curricula of six prominent countries in the Middle East in the field of dental sciences. Their selection was based on similarities and common cultural, economic and social characteristics. After collecting the selected curriculums, four steps including description, interpretation, juxtaposition and comparison were done. Tables were drawn based on goals such as the number of years of education, mission, general goals, and the role of graduates in the medical system of that country.
Results: The educational curriculum of the countries reviewed in the Middle East have many similarities in terms of the number of years of study in the field of dentistry, the general mission and goals, and the role of students in the medical system of that country. The main differences were in the number and type of teaching units in the curriculum of this countries. The method of teaching and the distribution of topics in the curricula of the countries differentiated them from each other. According to the results of this study, the curriculum of the countries of Iran, Saudi Arabia and the UAE were the most similar among the countries of the Middle East. The teaching method and distribution of topics in the curricula of countries distinguished them from each other.
Conclusion: Countries that are based on Russian language education have a shorter number of years of education and are similar to Russia. However, countries with an American educational base such as Saudi Arabia, the United Arab Emirates, and even Iran have a longer academic years and more general similarities in educational content.

Background and Aims: Incorrect prescription of antibiotics for odontogenic infections can endanger patients' lives. This study aimed to determine the pattern of antibiotic prescription by general dentists in Tehran and to compare it with the guidelines recommended by maxillofacial surgeons at Tehran University of Medical Sciences in 2019.
Materials and Methods: A cross-sectional study was conducted on 141 randomly selected dentists in Tehran. The dentists reported their antibiotic prescriptions for various odontogenic infections by completing a questionnaire. The frequency of prescribed antibiotics was calculated considering the severity of the infection, penicillin sensitivity, pregnancy and lactation status of women, and children. These were compared with the guidelines suggested by 15 maxillofacial surgery specialists at Tehran University of Medical Sciences in 2019. Descriptive analysis and binary logistic regression were used. Data analysis was performed using SPSS software version 25.
Results: Among patients sensitive to penicillin with severe infection, 61% of the dentists prescribed the correct medication. The correct prescription rate was 0% in patients with severe infection, 24.82% in pregnant and lactating women with mild infection, 65.24% in children with mild infection, 62.41% in patients with mild infection and penicillin sensitivity, 36.69% in children with severe infection, and 33.82% in pregnant and lactating women with severe infection. The results showed that older dentists were significantly more likely prescribe antibiotics correctly for odontogenic infections (P=0.036, B=0.28).
Conclusion: General dentists in Tehran did not optimally prescribe antibiotics for odontogenic infections. Therefore, training courses to improve their clinical performance are essential.

Guided bone and tissue regeneration is a common technique used in the treatment of areas around teeth and dental implants. In this framework, barrier membranes are employed to create a suitable environment that promotes new bone growth while preventing the invasion of foreign cellular components into this specific setting. Attributes such as biocompatibility with living tissues, structural integrity, longevity, and user-friendliness constitute the principal criteria for selecting appropriate membranes for this particular application. Given the extensive diversity of membrane types concerning their sources, texture, architecture, and inherent properties, determining the most suitable variant depends on the clinical condition presented by the patient and the specific treatment modality, thereby emphasizing its considerable importance. In recent years, fibrous membranes have garnered particular attention due to their distinctive characteristics. These membranes, made of natural or synthetic fibers, typically exhibit high porosity, which facilitates the ingress of vascular structures and osteogenic cells. Owing to their porosity and flexibility, fibrous membranes are considered exceptionally suitable for the regeneration of maxillofacial and dental tissues, thereby contributing to increase bone volume, guide its growth, and at the same time prevent soft tissue encroachment into the restoration area, which ultimately has a favorable effect on treatment outcomes. On the other hand, due to the complexity and extent of oral infections, new nanotechnological approaches have been proposed in recent years to reconstruct infected sites in dentistry. These strategies, by targeting specific sites and having non-toxic properties, can help deliver antimicrobial molecules, regenerate tissue, and maintain oral health. In this context, nanofibrous membranes serve as multifunctional structures, both in the controlled release of antimicrobial agents and as scaffolds for the formation of nascent tissue. Overall, fibrous membranes, by mimicking the physiological conditions of the organism, create an ideal environment for the growth and healing of bone tissues, leading to improved effectiveness in dental procedures. This article is devoted in detail to a comprehensive review of polymeric and composite fibrous membranes with drug release potential.

Background and Aims: Despite significant advancements in rehabilitation of edentulism with implants, complications such as implant failure before and after prosthetic loading remain concerns. This study aimed to evaluate the frequency of dental implant failure before and after prosthetic loading in some of Yazd dental clinics between 2018 and 2023.
Materials and Methods: In this descriptive cross-sectional study, 1060 patients’ files from three public dental clinics were reviewed. These patients were treated by dental implants between April 2018 and June 2023. The collected data included patients’ age and gender, implant diameter, brand, and placement site, type of prosthesis, and fixture failure after surgical and prosthetic phases. Data were statistically analyzed by independent t-tests and chi-square tests.
Results: The mean age of patients was 55.25 ± 12.37 years and 56.3% were female. The frequency of overall implant failure was 3.4%. The implant failure rate after prosthetic loading was 2.8% in females and 2.3% in males (P=0.47). This rate was 2% and 1.9% for maxillary and mandibular implants, respectively (P=0.5). This amount was 2.4% in molar areas,1.7% and 1.8% in premolar and anterior regions, respectively  (P=0.8). Implant failure rate was 1.3% in overdentures, 5.9% in cement-retained, and 3.2% in screw-retained prosthesis (P<0.001). This amount for implants with a diameter less than 3.75 mm was 2.6% and for those with a diameter more than 4.5 mm was 3.7% (P<0.001). Implants with a diameter less than 3.75 mm had a 2.6% failure rate, whereas those with a diameter greater than 4.5 mm had a 3.7% failure rate (P<0.001). The implants failure rate was 1.6% for Dio brand and 2.5% for Dentis (P=0.5).
Conclusion: The overall implant failure rate in this study was 3.4%, of which 1.5% occurred before and 1.9% occurred after prosthetic loading. The frequency of implant failure after loading was significantly associated with the implant diameter and prosthesis type. This was not related to the patient's gender, implant site, or the implant brand.

Background and Aims: The growing growth of dental services and the increasing competition among businesses in this field have made attracting new customers and retaining them a very difficult yet vital task for dental professionals. This has led to the emergence of the marketing function in dentistry and a look at international dental journals shows that in the past decades, researchers have paid increasing attention to the role of marketing in dentistry. They have examined and tested the impact and also how to formulate dental marketing strategies through theoretical studies and various scientific methods. For this reason, the purpose of the present study was to statistically examine the global trend of scientific productions related to marketing strategy in dentistry.
Materials and Methods: This research is a descriptive-analytical research in terms of its purpose, which was conducted using scientometrics and bibliometric analysis. In terms of time of this research, it is a cross-sectional research and based on the type of data, it is a quantitative research. The documents examined included all scientific articles published in English in the field of marketing strategy in dentistry, which were written by all researchers throughout the world until the end of 2025 and indexed in the PubMed, Web of Science, and Scopus databases. This research was conducted in January 2026.
Results: The results of the study indicated that the number of research related to the topic of "marketing strategies in dentistry" published in the PubMed, Web of Science, and Scopus databases from the beginning to 2025 was 365 documents and the dynamics of these researches were from 2017 to 2025. The largest number of researches was from 2025 with 40 works. The largest work in the field of marketing strategies in dentistry was by a researcher named Ball R with 10 scientific works. The British Dental Journal had the largest scientific production in this field with 23 works published. The largest number of researches in this field had been conducted in the United States with 225 works.
Conclusion: The results of the research indicated that marketing strategies today have taken a position beyond a mere marketing concept and have gradually emerged as a key process in dental research. The significant focus of scientific production on marketing studies, marketing strategies, and related outcomes in dentistry shows that marketing strategies play an important role in attracting patients, their satisfaction, the profitability of dental businesses, and the general health of society.