Showing 4 results for Adenoid
F. Baghaie Naeini , E. Yazdi , M. Seyed Majidi ,
Volume 15, Issue 4 (1-2003)
Abstract
The differential diagnosis between pleomorphic adenoma, the most common salivary gland neoplasm, microscopically, and two other common salivary gland neoplasms, meaning adenoid cystic carcinoma and mucoepidermoid carcinoma, is difficut.The purpose of this study was to determine the differences between pleomorphic adenoma, adenoid cystic carcinoma and mucoepidermoid carcinoma regarding the staining intensity with PTAH and H&E and also to investigate the relationship between staining intensity with PTAH and malignancy grade in mucoepidermoid carcinoma. 72 paraffin embeded samples including 24 pleomorphic adenoma, 24 adenoid cystic carcinoma and 24 mucoepidermoid carcinoma were selected and stained with PTAH. The staining intensity in total, in nucleus and cytoplasm of tumoral cells were evaluated and compared with H&E staining, statistically. The results were analyzed by Kruskal-Wallis, and Wilcoxon signed ranks tests (P<0.05).The logistic model was presented to predict the degree of malignancies through the assessment of nucleus and cytoplasm staining intensity in tumoral cells, and the patient's age. In this study, a statistically significant relationship was observed between staining intensity by PTAH and H& E in nucleus of tumoral cells in pleomorphic adenoma. Moreover, statistically significant relation between staining intensity by PTAH and H & E in cytoplasm of tumoral cells in adenoid cystic carcinoma was found. But there was no relation in other cases. On the other hand, a statistically significant relation between intensity of staining in total, in nucleus and cytoplasm of tumoral cells and the type of tumor was found. No relation was obtained between malignancy grade of mucoepidermoid carcinoma and staining intensity in total, in nucleus and cytoplasm of tumoral cells. The presented logistic model indicated a direct relation between tumor malignancy with patient's age and staining intensity in nucleus of tumoral cells, but a reverse relation was found between cytoplasm staining intensity in tumoral cells and tumor malignancy.Our findings show that PTAH and H & E staining methods, lead to similar results, however, PTAH staining is a reliable method in differential diagnosis of such salivary gland tumors.
Mh. Toodeh-Zaeim , H. Ravanmehr ,
Volume 17, Issue 4 (1-2005)
Abstract
Statement of Problem: The significance of adenoid tissue in Orthodontia appeared in 1954. At that time,even as today, orthodontists had an enduring interest in the relationship between excessive amounts of adenoid tissue, the developing occlusion, and facial morphology.
Purpose: The aim of this study was to evaluate effect of mouth breathing with adenoid enlargement on dentofacia! cephalometric measurements.
Material and Methods: A sample of 92 subjects between the ages of 6 and 15 years old were studied in two study and control groups. In study group, 46 mouth breathers (32 girls and 14 boys) with mean of 1 1.26 years old were examined by orthodontist and ENT specialist in order to confirmation of nasopharyngeal obstruction.Control group contained 46 nasal breathers (35 girls and 11 boys) with mean of 11.33 years old. For each patient in centric occlusion, a lateral cephalogram was taken and traced. 12 dentofacial variables were measured and statistical t-test was conducted by calculating the mean, standard deviation and p-value of parameters. Statistical t-test for mean oi~ dentofacial variables for the two groups revealed that some of variables were significantly different.
Results: In study group Z Go.Me-SN, Z Y-A.xis, Z Go, Z SN-PL variables were significantly higher than control group and Z HoFIl, Z SNB were significantly lower. The other dentofacial variables (ZS, IMPA,Z SNA, Z ANB. Z Ar and LH) didn't show any significant difference.
Conclusion: Adenoid enlargement and nasopharyngeal obstruction can affect dentofacial morphology and cause facial vertical growth pattern and upper centrals retrusion.
M. Eslami , N. Eshghyar , F. Ensani , S. Seifi ,
Volume 19, Issue 1 (4-2006)
Abstract
Background and Aim: The hormone receptor status in breast cancer has been pivotal in determining the likelihood of response to hormonal manipulation. Tumors which are both estrogen and progesterone receptor positive are much more likely to respond to anti-hormone therapy than negative tumors. There is well-established similarity between breast tissue and salivary glands. The aim of this study was to evaluate the progesterone receptor expression in pleomorphic adenoma and adenoid cystic carcinoma of salivary glands.
Materials and Methods: In this descriptive study, immunohistochemical staining with progesterone antibody was performed on 14 pleomorphic adenoma (PA) and 15 adenoid cystic carcinoma (ACC) paraffin blocks. The percentage of positive cells was determined using an eye piece graticule. Immunoreactivity was categorized as either positive (reactivity more than 5%) or negative (reactivity less than 5%). In addition the existence of progesterone receptor in tumor cells, stromal cells (fibroblasts), inflammatory cells and salivary glands around tumors was evaluated. Data were analyzed with T and Mann Whitney U tests with p<0.05 as the limit of significance.
Results: Immunohistochemical staining for progesterone receptor was negative in 15 ACC and 13 PA. Only one case of PA showed immunoreactivity for progesterone receptor. Also, 12 normal salivary glands around tumor were positive. Inflammatory cells, endothelial cells and fibroblasts did not show immunoreactivity in most cases.
Conclusion: The results indicate the lack of progesterone receptor expression in ACC and PA of salivary glands.
Z. Dalili , S. Rahro Taban , Ma. Vahedi ,
Volume 19, Issue 2 (5-2006)
Abstract
Background and Aim: Adenoids are normally large in children and their size starts to reduce during adolescence. Hypertrophic adenoids could be associated with allergic reactions. Enlarged adenoids result in nasal breathing difficulties and the child is forced to switch to mouth breathing. Airway obstruction causes postural alterations of jaw, tongue and head, and due to persistent obstruction, patient’s appearance changes to adenoid face. Evaluation of nasopharyngeal space in lateral cephalometic view is a simple and repeatable method for determination of the size and shape of adenoids and nasopharyngeal space which can provide a simple measurement of nasopharyngeal obstruction. The roof of nasopharyngeal space is covered by the sphenoid bone. Thus changes of nasorespiratory resistance by hypertrophic adenoids may affect the cranial base angles. In this study, the relationship between adenoid hypertrophy and cranial base angles was investigated.
Materials and Methods: In this descriptive-analytic study, lateral cephalometric views of 7 to 14 y/o patients from the files of orthodontic centers in Rasht city were selected. The radiographs with proper resolution were separated for this research. Adenoid to nasorespiratory ratio (A/N Ratio) was determined by Fujioka method and categorized in three groups: A (A/N 0.8), B (0.5
