Journal of Dental Medicine

Background and Aim: Researches have shown that bacteria play the main role in development of pulpal and periapical diseases. Chemo-mechanical cleaning of infected root-canal system can not remove all of the microorganisms. Thus interappointment medicaments are necessary to aid this goal. Calcium hydroxide is one of the most useful medicaments in root canal therapy, but this medicament can not eliminated all of the bacteria in root canal system. Carvacrol is an edible plant extract that has antimicrobial and anti-inflammatory effects. If this extract is effective against endodontic bacteria, it can be used as an root canal medicament.

Materials and Methods: In this experimental study, Initially, MIC and MBC of carvacrol detected with Macro broth dilution method and determined as 0.3% and 0.6%, respectively. After that, 30 single root and single canal extracted human teeth were used in this study. The number of specimens determined in a pilot study on 4 extracted teeth. After preparation to apical size # 30 with hand and rotary instruments, teeth were randomly divided into two experimental and two control groups. After culturing Enterococcus faecalis in prepared canals, we used emulsion of 0.6% carvacrol and calcium hydroxide in two A and B experimental groups for 7 days as the intracanal medicament. Microbial samples obtained before and after experiment. Then, canals with negative culture selected to obtain dentinal shaving to culture. Data obtained from microbiological samples analyzed with kruskal-wallis and Bonferroni tests.

Results: Results of this study showed that emulsion of 0.6% carvacrol has no significant difference with calcium hydroxide in elimination enterococcus faecalis after 7 days dressing (p>0.05).

Conclusion: Carvacrol can be used as an intrappointment intracanal medicament.

Background and Aims: It is important to use intracanal medicaments in teeth with necrotic pulp. Calcium hydroxide is the intracanal medicament of choice in such cases. Also, Mineral Trioxide Aggregate (MTA) is a suitable root canal filling material because of its favorable characteristics. MTA can be used in some cases where calcium hydroxide is used. The purpose of this study was to evaluate the Ca++ and OH ˉ diffusion through root dentin using calcium hydroxide paste and two different brands of MTA as root canal filling materials.
Materials and Methods: In this in vitro study, the root canals of 52 single-rooted teeth were instrumented and shaped. External defects were created on the middle one-third of the root surface. 17% EDTA and 5% NaOCl were used to remove the smear layer. All surfaces except the external defects were sealed and the teeth were placed in normal saline. Ten teeth were selected as the control group. Forty-two remaining teeth were divided into three groups of 14 teeth each (A,B, and C groups). ProRoot MTA was placed in group A. Angelus MTA was placed in group B and Calcium hydroxide paste was placed in group C. After sealing the coronal access, all specimens were placed in normal saline solution. Ca++ concentration and pH were determined after 24 hours, 48 hours and one week in all groups. The data were analyzed with Repeated Measure ANOVA and Pair T- tests.
Results: Ca++ release and pH in group C was significantly higher than those in groups A and B in all time periods (P<0.001). The difference between groups A and B was not significant (P>0.05).
Conclusion: The results of this study indicate that in necrotic cases with lesion which MTA is indicated (open apex and perforation), calcium hydroxide might be better used as an intracanal dressing before using MTA as a permanent filling material.