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Showing 3 results for Impacted Third Molar
An assessment on the effects of mandibular impacted third molar surgery on the periodontium of the adjacent molar
M. Ramezanian ,
Volume 16, Issue 1 (4-2003)
Abstract
Statement of Problem: One of the important indications for the extraction of mandibular impacted third molar is to preserve the periodontal health of the adjacent second molar from the destructive effects of plaque accumulation, acute and chronic inflammation.
Aim: The purpose of this study was to determine the effect of mandibular third molar surgery on the PDL of the adjacent molar.
Materials and Methods: Thirty patients, referred to the department of maxillofacial surgery, Tehran University of Medical Sciences, were selected, based on the desirable conditions. They had no history of systemic diseases and their adjacent molar was healthy. Probing depth (PD) at seven points and attachment level (AL) at three points were measured preoperatively. Standardized periapical radiographics were taken regularly for all patients. All the above-mentioned procedures repeated after three months of surgery. Findings were analyzed by Paired t-test.
Results: A significant difference in probing depth (PD) was observed before and after surgery, meaning that probing depth decreased after mandibular third molar surgery. Attachment level was also decreased post operatively moreover. Intrabony defects (IBD) showed healing after surgery.
Conclusion: Considering the limitations of the present study, impacted third molar surgery is suggested to prevent periodontal problems of the adjacent molar.
The effect of Diazepam in pain reduction following mandibular impacted third molar surgery
M.e. Daneshvar ,
Volume 16, Issue 4 (1-2004)
Abstract

Statement of Problem: Pain control is of high importance in dentistry. Prescribing sedatives such a Diazepam, as an anti-depressant and pain threshold elevator drug is able to influence the patient's reaction to pain and reduce it.
Purpose: The aim of the current study was to evaluate the effect of Diazepam in pain reduction following mandibular impacted third molar surgery.
Materials and Methods: In this study, which was conducted in the department of Oral and Maxillofacial surgery Faculty of Dentistry, Tehran University of Medical sciences. The patients were divided into two equal groups (n=30). For controls, antibiotics and analgesics were prescribed after surgery. However, except the aforementioned drugs, Diazepam (5mg), three times per day, was prescribed for the experimental group. The amount of mouth opening was also measured as an auxiliary sign after one week. The data were compared by
X2 test after one week.
Results: 60% of the experimental group and 13.8% of the control group felt a weak pain. Statistically significant differences were observed regarding pain feeling between two groups (P<0.001). Severe pain feeling was 34.5% and 10%, for control and experimental groups, respectively.

Conclusion: It is suggested that Diazepam is an effective pain reduction drug following third molar surgery.This drug has also a relative effect on temporary trismus resulting probably from muscle trauma or pain.


Evaluation of the effect of tranexamic acid with Gelfoam carrier in preventing dry socket syndrome following surgical removal of impacted mandibular third molars
Misagh Mohajer, Hassan Mesgari, Behnaz Pourian, Javad Nosrati Momvandi, Masoud Hassanzadeh,
Volume 39, Issue 0 (3-2026)
Abstract
Background and Aims: Dry socket is one of the most common complications following dental surgery. Therefore, effective prevention of dry socket can significantly improve patient recovery after tooth extraction. The aim of this study was to evaluate the effect of tranexamic acid combined with a Gelfoam carrier on the prevention of dry socket following surgical removal of impacted mandibular third molars.
Materials and Methods: This parallel randomized clinical trial was conducted in 2023 on 72 patients (40 in the intervention group and 32 in the control group) at the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Islamic Azad University, Tehran Unit. In the intervention group, 250 mg of tranexamic acid powder was placed into the extraction socket and covered with Gelfoam, whereas the control group received sterile gauze only. The diagnosis of dry socket was made 2–3 days postoperatively by an independent surgeon. Statistical analysis was performed using the chi-square test, likelihood ratio, and Fisher’s exact test, with a significance level set at P<0.05.
Results: The incidence of dry socket was 7.5% in the intervention group and 34.4% in the control group. All statistical tests demonstrated a significant reduction in the occurrence of dry socket in the intervention group (P≤0.005). These findings are consistent with the physiological mechanism of tranexamic acid in inhibiting fibrinolysis and stabilizing the blood clot, resulting in a marked reduction compared with the control group.
Conclusion: Topical application of the tranexamic acid in combination with Gelfoam following extraction of impacted third molars is an effective, simple, and cost-effective method for the prevention of dry socket. For broader clinical recommendation, further studies with larger sample sizes, comparisons with existing standard preventive methods, and longer follow-up periods are suggested.

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