N. Takzaree , K. yarmohammadi , Ar. Takzaree , H. semiyari. , M. Akbari ,
Volume 14, Issue 4 (1-2002)
Abstract
Pain reduction and surgical wound healing enhancement have several advantages. Wound healing is a complex and organized phenomenon. During this phenomenon, definite and harmonized processes such as: reconstruction, immigration parenchyma and connective tissue cells proliferation and re-construction of gingival connective tissue take place. Studies show that lower power laser (He-Ne) can induce different biological changes in ceils through biochemical mechanisms. Considering the therapeutic effects of (He-Ne) low power laser radiation on healing processes, cell proliferation, connective tissue fibers and finally the acceleration of gingival wound healing were studied. This study was done on 50 mature and healthy rats with the average weight of 250 to 300 grams, and 3 to 4 months old. After anesthesia, maxillary wounds, with the same size, were made in all samples and they were randomly divided into control and test groups. After surgery, rats of test group received laser radiation with the value of 5 mJ/cm3 every day for a period of 5 days. And on the 5lh day, they were killed. Gingival biopsy was performed and histological study was done. The number of fibroblasts, collagens, endothelial ceils and blood vessels were counted. In test group, the granulation tissue was more active and the edema and inflammation were lesser than those of the control group. Data were analyzed by t-test method and PO.05 was significant. So, it is concluded that periodical radiation of (He-Ne) low power laser has an important role on surgical gingival wounds.
Neda Moslemi, Mohadeseh Heidari, Reza Fekrazad, Hanieh Nokhbatolfoghahaie, Siamak Yaghobee, Ahmadreza Shamshiri, Mozhgan Paknejad,
Volume 27, Issue 1 (4-2014)
Abstract
Background and Aims : Free gingival graft is one of the most predictable procedures for gingival augmentation, but patient’s discomfort and pain during healing period of palatal donor site is a significant concern. The aim of this study was to evaluate the effect of 660nm low power laser on pain and healing in palatal donor sites.
Materials and Methods: The present split mouth randomized controlled clinical trial was performed in 12 patients at the department of periodontics of Tehran University of Medical Sciences. Patients’ allocation was done by balanced block randomization (laser group and placebo group). In laser test group (wave length: 660 nm, power: 200mW, time of irradiation: 32s) was applied immediately post-surgery and in day 1, 2, 4 and 7 after that. In the control group, laser application was done with off power mode. Evaluation of epithelialization and healing was done with H2O2 and photograph. The number of palliative pills and bleeding was recorded. Wilcoxon test was used to analyze healing during the study. Patient’s pain during study was analyzed using repeated measure ANOVA. Mc Nemar test was used to analyze bleeding. Level of statistical significance was set at 0.05.
Results: Laser group showed better epithelialization (P=0.02) and healing (P=0.01) in day 14 after surgery and showed better epithelialization in day 21(P=0.05). No statistically differences were observed between laser group and control group in terms of bleeding and medication (P=0.51), (P=1).
Conclusion: According to the results of this study, the low power laser can promote palatal wound healing during the second and third week after free gingival graft procedures.
