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Showing 3 results for Nano-Hydroxyapatite
Evaluation of Iranian toothpaste containing different concentrations of nano-hydroxyapatite on the remineralization of incipient carious lesions: in vitro
Haghgoo Roza , Rezvani Mohammad Bagher , Haghgoo Hamid Reaza , Ameli Nazila , Zeinabadi Mehdi Salehi ,
Volume 27, Issue 4 (1-2015)
Abstract

  Background and Aims: Dental caries is one of the most common infectious diseases which could be prevented in various ways. The aim of the present study was to evaluate the effect of a toothpaste containing different concentrations of nano-hydroxyapatite on the remineralization of incipient caries.

  Materials and Methods: 9 sound first premolar teeth of maxilla and mandible were sectioned to four pieces. 6 specimens were stored in distilled water as control group. The remaining 30 specimens were demineralized for 72 hours and then their microhardness was measured. 0, 0.5, 1, 2 and 5% wt nano-hydroxyapatite were added to the solution of distilled water and toothpaste. Specimens were divided into 5 groups (N=6) and after demineralization, each group were randomly immersed in the above-mentioned solutions for 15 minutes. Next, specimens were kept in artificial saliva for 1 hour followed by immersion in the related remineralizing solution for another 15 minutes. This procedure was repeated for 5 days. Finally, the microhardness of the teeth was measured. Data were analyzed using repeated measures analysis of variance (ANOVA).

  Results: The microhardness of demineralized teeth was increased following exposure to different concentrations of nano-hydroxyapatite, but this increase was not statistically significant (P=0.62).

  Conclusion: Nano-hydroxy apatite can enhance remineralization and increase the tooth microhardness although this increase was not significant.


The effect of nano-hydroxyappatite solution on the permanent tooth remineralization following exposure to soft beer (in situ)
Haghgoo Roza , Haghgou Hamid Reza , Abbasi Farid , Tavakkoli Mohammad ,
Volume 27, Issue 4 (1-2015)
Abstract

  Background and Aims: The main cause of erosion is acid exposure . Side effects of erosion necessitate therapeutic agents’ uses. The aim of this study was to investigate the effects of nano- hydroxy apatite in tooth remineralization following exposure to soft beer.

  Materials and Methods: This in vitro experimental study was conducted on 18 human impacted third molars that had been surgically extracted. The microhardness of specimens was measured. Then teeth were exposed to soft beer and their secondary microhardness was measured. The teeth were divided into 2 groups (water and nano-hydroxy apatite solution) and were placed on 9 orthodontics appliances and delivered to 9 volunteers. These volunteers placed the tooth on one side in water for 5 minutes and the tooth in opposite side in nano-hydroxyapatite solution. This application was repeated 6 times a day for 10 days. The microhardness of teeth was measured again. Data were analyzed using Paired T-test.

  Results: The tooth enamel microhardness reduced after exposure to soft beer significantly (P=0.04). The microhardness of 9 teeth after being in water showed significant changes (P=0.012). The microhardness of 9 teeth significantly changed after exposure to nano -hydroxyapatite solution (P=0.001) .

  Conclusion: Based on the results of this study, 10% solution of nano- hydroxy appatite could restore the erosive lesions .


Comparison of dentinal tubules closure under the effect of carbonated nano structural hydroxyapatite toothpaste produced inside the country with fluoride toothpaste
Rahelesadat Mirseifi Nejad Naini, Alireza Daneshkazemi, Fahime Shafiee,
Volume 31, Issue 2 (9-2018)
Abstract
Background and Aims: Increased tooth sensitivity is a common dental problem. One of the mechanisms of dentin hypersensitivity treatment is blocking dentinal tubules. The aim of this study was to compare the average closing dentinal tubules affected by carbonated Nano-hydroxyapatite and fluoride toothpaste using scanning electron microscope (SEM).
Materials and Methods: The enamel of gingival buccal crown surfaces of 42 sound maxillary premolars teeth were removed until the dentin surfaces were exposed. The dentine specimens of 3×3 mm were prepared. The specimens were washed by distilled water after etching and randomly divided into 6 groups. 3 groups were interfered with the carbonated nano-hydroxyapatite toothpaste and the other three groups interfered with Colgate toothpaste in 3, 7 and 14 days. The samples were examined by SEM to check the status of dentinal tubules. Then, they were evaluated by two researchers according to the Hulsmann index. Data were analyzed by using SPSS23 software and Kruskal-Wallis statistical test. The significance level of 0.05 was considered.
Results: The amount of dentinal tubules closure by the two toothpastes was significantly different. This difference was higher in the hydroxyapatite toothpaste than fluoride which were (P=0.024, 0.004 and 0.000), respectively. There were no significant differences among the groups in 3,7 and 14 days (P=0.230, 0.069, 0.537).
Conclusion: The toothpaste containing carbonated nano structural hydroxyapatite was more successful in closing dentinal tubules than Colgate toothpaste in short period of time.

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