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Showing 2 results for Nickel
Biocompatibility evaluation of Minalux and VeraBond2 in-vitro
M. Kandi Bidgoli , A. Mirfazaelian , Sn. Ostald ,
Volume 18, Issue 1 (3-2005)
Abstract

Statement of Problem: One of newly presented base metal alloys (Minalux) is produced according to VeraBond2 alloy (Ni- Cr base) composition. Several studies showed that, cytotoxicity of base metal alloys can be occurred due to corrosion and element release.

Purpose: This study evaluated the biocompatibility of these two base metal alloys in three steps: as cast, after polishing and after porcelain firing cycles. Release of Ni and Cr ions were measured to determine if there is any difference between these two alloys.

Materials and Methods: Samples of two base metal alloys were subjected to Neutral Red Assay, MTT Assay and Trypan Blue for biocompatibility tests. Fibroblast Balb/c 3T3 cells were used for cell culture. Samples were contacted directly with cells in 37ºc and 5% Co2 concentration for 72 hours. Teflon samples were used as negative control. ANOVA test was used to compare different groups of two alloys. In addition, the release of Ni and Cr ions in to saline solution was measured by means of atomic absorption spectrometry.

Results: MTT and Trypan Blue didn’t show any significant difference between Minalux, VeraBond2 and Teflon. Neutral Red Assay showed no significant difference between these two base metal alloys but as cast group was higher in cytotoxicity in comparisons with polished and firing groups in both two alloys. Release of Cr ion was non detectable (Cr < 1 PPB) but Ni ion was measured and Ni release was significantly different in as cast groups (P=0.007) of two alloys.

Conclusion: There is no significant difference between cytotoxicity of two base metal alloys and polishing and firing can decrease cytotoxicity of both alloys.


Assessment of the rate of orthodontic appliances ion release in different mouthwashes: An overview
Seyyed Amirhossein Mirhashemi, Sahar Jahangiri, Mina Mahdavi Moghaddam, Rashin Bahrami,
Volume 32, Issue 4 (1-2020)
Abstract

Background and Aims: All metal components of orthodontic appliances are somewhat corroded in the oral environment due to some changes in chemical, mechanical, thermal, microbiological and enzymatic factors which facilitates ion release. Ionic release can result in a discoloration of the surrounding soft tissue or allergic reactions in sensitive patients or even local pain in the area. In general, ions can cause toxic and biological side effects if their values reach the threshold, so the release of ions from the metal components of orthodontic appliances is important to us. The aim of this review article to determine the rate of orthodontic appliances ion release in different solutions.
Materials and Methods: A review of the literature was carried out in Pubmed, Google Scholare and Web of science database using selected key words (Saliva/ Titanium/Normal Saline/ Ion release Orthodontic appliance/Mouth wash/ Nickel/ Chromium). These searches were limited to the articles published from 2005 to 2018. According to the inclusion and exclusion criteria, 25 articles were obtained.
Results: Because of conflicts in the reported results, it was necessary to synchronize the measurement methods and also to use artificial saliva medium with normal pH as a control to achieve better systematic comparison.
Conclusion: There was significant differences in the ion release between mouthwashes. In all studies, the effect of pH and acidity has been shown to increase the release of these ions. In addition, stainless steel (SS) instruments had the least biocompatibility among all types of alloys evaluated.

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