Showing 7 results for Odontogenic
A. Forouzandeh ,
Volume 11, Issue 4 (8-1998)
Abstract
The goal of this review was to determine the prevalence of cysts in the oral and maxillofacial regions, specially odontogenic cysts, as determined by age, sex and location.This research reviewed 6826 biopsies from department of oral pathology school of dentistry at the medical sciences university of Tehran from 1360-1376 (1981-1997).The results obtained revealed that 19.48% of biopsy lesions were cysts of osseous structures, of which 81.9% were odontogenic cysts, 12.4% psuedocyst and 5.7% were Non- odontogenic in origin.The most common lesions of the oral cavity were odontogenic cysts of which the subgroup of radicular cysts (which belong to the category of inflammatory odontogenic cysts) consisted of 49.15% radicular cysts occurred with the higher incidence in males in their third decade of life and were found most commonly associated with the upper jaw.Dentigerous cysts fall in the second most common group at 25.71% of odontogenic cysts.These cysts had a male predilection with a peak incidence in the second decade and were most common in the lower jaw.In the third group were the keratinized odontogenic cysts at 19.25%. These cysts had a male predilection with a peak incidence in the third decade and the lower jaws were twice as likely to be involved as the upper jaw. Other types of odontogenic cysts were noted to be less common in occurrence.In this study it was discovered that mcoceles consisted of 63.5% of pseudocysts and were found most commonly in the lower lip, with surgical ciliated cysts at 33.7% were the most common Non- odontogenic cysts and were found exclusively in the upper jaw adjacent to the maxillary sinus.Over all it can be stated that about y5 of all oral and maxillofacial lesions were cysts.The most common cysts were odontogenic cysts which due to their higher prevalence and various types, most be carefully examined at the histopathological level to diagnose and therefore administer definitive treatment.
N. Eshghyar , N. Jalayer Naderi , P. Sarraf ,
Volume 18, Issue 1 (3-2005)
Abstract
Statement of Problem: Odontogenic keratocyst is a developmental odontogenic cyst which arises from dental lamina. One of the important features of odontogenic keratocyst is strong tendency to recurrence.
Purpose: The purpose of this study was the statistical evaluation of age and gender of patient as well as area of involvement in odontogenic keratocysts in the oral and maxillofacial pathology department of dental faculty of Tehran University of Medical Sciences from 1971-2002. Materials and Methods: This study was a cross sectional, descriptive one. Medical records were reviewed and variables such as age, gender and site of involvement were recorded. The data were analyzed with SPSS software.
Results: The relative frequency of odontogenic keratocyst was 36%. 66% of cysts were in men and 34% in women. 68% of lesions affected the lower jaw and 32% the upper jaw. Regarding the site of involvement, 48% of lesions involved the molar region of mandible and 42%, the anterior part of maxilla. The occurrence of keratocysts was higher in this sites. Most of the cases were diagnosed in the third decade.
Conclusion: Based on the findings of this study, odontogenic keratocyst was more prevalent in men, mandible and the third decade. The posterior part of mandible and anterior region of maxilla were involved most frequently.
B. Seraj , P. Motahhari , M. Fakhri , R. Ahmadi ,
Volume 20, Issue 2 (5-2007)
Abstract
Odontomas are benign tumors of odontogenic origin characterized by their slow growth. They are considered to be a common type of odontogenic tumor, but rarely occur in the primary dentition.The etiology of odontomas is unknown, although local trauma, infection and genetic factors have been suggested. Odontomas often cause disturbances in the eruption of teeth such as, impaction or delayed eruption, and retention of primary teeth and abnormalities in the position of teeth such as tipping or displacement of adjacent teeth. In this paper, a case of unerupted right mandibular primary cuspid in a 5 years old girl due to the presence of a compound odontoma is presented.
Samaneh Bayat, Shirin Sakhdari, Ali Mokhtar, Ali Lotfi, Mehdi Amiri Siavashani,
Volume 28, Issue 4 (1-2016)
Abstract
Background and Aims: Central odontogenic fibroma is a rare odontogenic neoplasm that originates from odontogenic ectomesenchyme. Most cases occur in the mandible and between the ages of 11 and 39 years. The neoplasm shows a definite female preponderance, with a ratio of 2.2:1 and has a very low recurrence rate. The aim of this article was to report a case of this rare lesion which was accidentaly found.
Case Report: A 11-year-old female, during her orthodontic treatment and without any complain and any sign or symptoms, performed a panoramic image for assessing the permanent teeth buds. In the panoramic view a unilocular radiolucent lesion with well-defined and corticated borders in the right mandibular body region was evident. The lesion was treated with simple excision. Simple type of central odontogenic fibroma histopathologic features was observed in the microscopic view.
Conclusion: Although the central odontogenic fibroma is a rare benign neoplasm, however, a careful evaluation of radiographic images is important for early detection of lesions because the patient may have no clinical symptoms such as swelling, pain and paresthesia.
Forooz Keshani, Neda Kargahi, Maedeh Omani,
Volume 35, Issue 0 (5-2022)
Abstract
Background and Aims: Cathepsin-D is a well-known protease that promotes invasion in tumoral lesions. Considering the cystic neoplasm nature of odontogenic keratocyst (OKC), the aim of this study was to compare the expression of cathepsin-D in this lesion with the unicystic ameloblastoma (UA) and orthokeratinized odontogenic cyst (OOC) for better understanding of its behavior.
Materials and Methods: In this descriptive-analytical study, we used paraffin blocks available in the archives of oral and maxillofacial pathology department of dental school (8 unicystic ameloblastoma (UA), 8 odontogenic keratocyst (OKC) and 8 orthokeratinized odontogenic cysts (OOC)) which they were stained immunohistochemically with cathepsin-D. Then, the samples were observed simultaneously by two oral pathologists for detection the intensity and pattern of epithelial and stromal cells staining. Data were analyzed by SPSS20 and Kruskal-Wallis, Mann-Whitney and Chi-square test (P<0.05).
Results: The staining intensity of the epithelial cells of UA group was significantly more than OOC and OKC (P=0.02). The staining intensity of the stromal cells of UA was more than the other two groups, although this difference was not statistically significant (P=0.32). The pattern of cell staining in epithelium and stroma did not show any significant difference between the three groups in this study (P=0.15, 0.22).
Conclusion: The results of this study regarding the intensity expression of cathepsin-D in these three odontogenic lesions could be considered as a probable evidence for the new odontogenic lesions classification (WHO2017) in terms of reintroducing OKC as an odontogenic cyst. If this idea is rejected, it seems that cathepsin-D expression is not associated with the invasive behavior of this cyst, and further investigation of other markers in the epithelium and stroma simultaneously is suggested for a better understanding of its biological nature.
Arash Sarrafzadeh, Maryam Mohebiniya, Soheila Jadidi,
Volume 36, Issue 0 (5-2023)
Abstract
Background and Aims: The incisive canal cyst also known as nasopalatine duct cyst (NPDC) is the most common developmental non odontogenic cyst and it is usually asymptomatic with a well corticated round, ovoid or in some cases unique heart shaped radiolucent radiographic finding. Its accurate diagnosis from odontogenic cysts, odontogenic tumor, and benign non-odontogenic tumors using clinical and radiographic findings leads to eradication of pathologic condition with minimum residual defects and patient discomfort. In this case report, the clinical and radiographic findings of a 60-year-old female with the chief complaint of swelling was reviewed. There were typical histologic and radiographic findings related to nasopalatine duct cyst. The surgical management is explained. Follow up visit showed satisfactory healing and no dehiscence. It could be suggested that heart shaped radiographic finding in 3-D reconstructed image in the maxillary midline would be a good predictor for NPDC.
Nima Dehghani, Mohadeseh Azarsina, Xaniar Mahmoudi,
Volume 38, Issue 0 (4-2025)
Abstract
Background and Aims: Incorrect prescription of antibiotics for odontogenic infections can endanger patients' lives. This study aimed to determine the pattern of antibiotic prescription by general dentists in Tehran and to compare it with the guidelines recommended by maxillofacial surgeons at Tehran University of Medical Sciences in 2019.
Materials and Methods: A cross-sectional study was conducted on 141 randomly selected dentists in Tehran. The dentists reported their antibiotic prescriptions for various odontogenic infections by completing a questionnaire. The frequency of prescribed antibiotics was calculated considering the severity of the infection, penicillin sensitivity, pregnancy and lactation status of women, and children. These were compared with the guidelines suggested by 15 maxillofacial surgery specialists at Tehran University of Medical Sciences in 2019. Descriptive analysis and binary logistic regression were used. Data analysis was performed using SPSS software version 25.
Results: Among patients sensitive to penicillin with severe infection, 61% of the dentists prescribed the correct medication. The correct prescription rate was 0% in patients with severe infection, 24.82% in pregnant and lactating women with mild infection, 65.24% in children with mild infection, 62.41% in patients with mild infection and penicillin sensitivity, 36.69% in children with severe infection, and 33.82% in pregnant and lactating women with severe infection. The results showed that older dentists were significantly more likely prescribe antibiotics correctly for odontogenic infections (P=0.036, B=0.28).
Conclusion: General dentists in Tehran did not optimally prescribe antibiotics for odontogenic infections. Therefore, training courses to improve their clinical performance are essential.
