Journal of Dental Medicine

Background and Aim: Lead is one of the most dangerous metallic poisons which can lead to acute and chronic poisoning with a broad range of systemic and oral signs. The aim of this study was to evaluate the relationship between the prevalence of oral complications and blood lead level in workers employed in Koushk lead mines, Yazd province.

Materials and Methods: This analytical study was conducted on 70 subjects employed in Koushk lead mines and 70 workers in Yazdbaf textile factory as control group. A questionnaire including demographic information and medical questions was completed for each case and oral manifestations were recorded, as well. Blood samples were taken from subjects and blood lead level was measured by atomic absorption spectrophotometer. Data were analyzed using t, Chi-Square and Mann Whitney tests with p<0.05 as the limit of significance.

Results: The mean lead level was 7.06 µg/dl in case group and 4.97µg/dl in control group (P= 0.039). In case group, 3 subjects had blood lead level more than 20µg/dl. Statistical analysis showed significant differences regarding neurologic disorder, chronic fatigue, existence of lead line, mucous pigmentation, gingivitis, tongue burning, taste sense reduction and DMF between case and control groups (P<0.05).

Conclusion: Based on the results of this study, since the mean blood lead level in mine workers was in normal limits, the observed symptoms were not related to systemic poisoning. Direct contact of the oral mucosa with the lead in breathing air or other factors related to overall health problems in mine workers may be responsible for the present findings. Further studies are recommended on similar subjects working in different conditions.

  Background and Aims: AIDS-associated oral lesions are important, in terms of diagnostic-prognostic role and monitoring patients moreover some of them may reduce patient’s quality of life. The aim of this study was to determine the prevalence of oral lesions in HIV patients.

  Materials and Methods: This descriptive cross-sectional study was carried out among a total of 62 HIV⁺ patients who attended a counseling and treatment center in Rasht. Demographic information, drugs and laboratory status were extracted from patients’ files. Data were analyzed using univariate and multivariate logistic regressions with multiple linear regressions.

  Results: From 62 cases, 50 were male and 12 female and the mean age was 40.5±11.3 years. 59 patients had oral lesions including periodontal disease (95%). The most prevalent oral lesions included: periodontitis (67.7%), oral candidiasis (41.9%) of erythematous (35.4%) and pseudomembranous types (6.45%) and angular cheilitis (12.9%). Patients with removable denture presented a higher rate of erythematous candidiasis and angular cheilitis (P=0.001). In this study, periodontal diseases were rosed by the post-diagnosis years (P=0.024) and the antiretroviral medications (P=0.002). Patients on the prophylactic medications (P=0.043) were less likely to have erythematous candidiasis age may caused angular cheilitis (P=0.041). Pseudomembranous candidiasis was inversely correlated with CD₄ + L levels (P=0.052).

  Conclusion: The majority of the cases in this study were IV drug user males within the 4th decade of life. Although oral lesions were not common, but the dental and periodontal statuses exhibited poor oral hygiene which need more attention.