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Showing 3 results for Tongue
An investigation on therapeutic effect of zinc sulfate in patients with geographic tongue
H Abdolsamadi , M. Hamian ,
Volume 18, Issue 4 (1-2006)
Abstract

Background and Aim: Geographic tongue (GT) is a relatively common lesion which is usually asymptomatic and found during routine examinations. Lesions may be single or multiple and frequently are confined to the dorsal surface and lateral borders of the tongue. Although the cause is unknown, zinc deficiency has been suggested as a possible etiologic factor. The purpose of the present study was to determine the therapeutic effect of zinc sulfate in patients with geographic tongue.

Materials and Methods: This study was a randomized double blind clinical trial performed on 40 cases. 20 patients in experimental group were given zinc sulfate and 20 patients in control group took placebo. Slides were taken at the first day and healing was recorded after 10 days. Data were analyzed using chi-square test with P<0.05 as the limit of significance.

Results: In 16 cases of the experimental group and in 3 cases of the control group signs of healing were observed.

Conclusion: Regarding the role of zinc in epithelial tissues health and development of filliform papillas and in spite of the positive effect of zinc sulfate in treatment of geographic tongue, further investigations concerning its effects on other mucosal conditions are recommended.


Evaluation of microvascular density by CD34 in squamous cell carcinoma of the tongue and its relationship with cervical lymph node metastasis
N. Eshghyar, P. Motahhary, S. Rahrotaban,
Volume 21, Issue 4 (1-2009)
Abstract

Background and Aim: Angiogenesis plays a central role for development and progression of malignant tumors.It is considered as an important factor for predicting of malignant tumor's behavior such as metastasis to lymph nodes and other clinicopathologic factors. However , it is still a controversial factor especially in oral squamous cell carcinoma.The aim of this study was to evaluate the correlation between angiogenesis and clinicopathologic parameters such as presence of metastatic cervical lymph node in the tongue squamous cell carcinoma.

Materials and Methods: In this cross-sectional study, 40 cases of squamous cell carcinoma of the tongue were selected from the archive of cancer institute of Tehran University of Medical Science. Sections were prepared from paraffin blocks and immunohistochemically stained with antibody against CD34. Stained vessels were counted in 4 fields ,the most vascular areas at low magnification, in each areas of intratumoral ,peritumoral and nontumoral adjacent tissue in two groups with metastatic lymphnodes (N+) and without (N-). The average counts from the four most vascular areas were recorded as the mean microvascular density (MVD). Data were analyzed by 3wayANOVA and Independent T- test with p<0.05 as the level of significance.

Results: High mean MVD-CD34 was significantly correlate with positive cervical lymph node metastasis in intra tumoral and peritumoral areas but there was no significant correlation between mean MVD-CD34 and age, gender, and differentiation of tumor.

Conclusion: Based on the results of this study, CD34 can help us to determine the presence of cervical lymph node metastasis and may also determine the outcome of a primary squamous cell carcinoma of the tongue.


Cephalometric evaluation of tongue position and oropharynx space in children treated with Twin-block appliance
Sarvin Sarmadi, Behrad Tanbakuchi, Javad Chalipa, Fahimeh Salimi, Mehrdad Panjnoosh,
Volume 31, Issue 1 (6-2018)
Abstract
Background and Aims: Functional therapy locates the mandible in a more anterior and inferior position. Tongue posture and oropharynx space have a considerable relationship with mandibular posture. The aim of the present study was to determine the changes of tongue posture and oropharynx space following treatment with Twin block appliance in adolescent patients with class II division 1 ma1occlusion.
Materials and Methods: Twenty two patients (14 girls mean age:11.5, 8 boys mean age:12.5 years) who were treated with twin-block appliance were enrolled. Cephalograms were used to assess the linear measurements. Graber pattern and McNamara parameter were used to evaluate the tongue posture and oropharynx space, respectively. Data analysis was performed by paired t-test.
Results: The findings of the present study showed a significant increase in anterior position of tongue (P=0.06). Oropharynx space was increased significantly (P<0.001). There was a significant correlation between the decrease of ANB and anteroposterior increase of oropharynx space.
Conclusion: Twin-block appliance caused considerable forward movement of tongue and significant increase of oropharynx space in the sagittal plan.

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