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Vahid Kazemizadeh, Nasser Behpour,
Volume 12, Issue 1 (3-2022)
Abstract

Introduction: Sleep deprivation is one of the factors affecting the physiological performance of athletes and laboratory evidence has suggested a link between sleep deprivation and decreased physical performance of athletes. The aim of this study was to determine the effect of sleep deprivation on objective and subjective physiological responses of student-athletes.
Material and Methods: The research is experimental. Twenty male volunteer sports science students selected and examined in two conditions with simple random selection in counter balanced intra-group pattern. Participants examined at two controlled situation; 1) after twelve hours fasting and eight hours enough sleep, and 2) after twelve hours fasting and thirty hours quiet sleeplessness. Measurements of physiological variables including: blood pressure, heart rate, blood lactate, mental scale of pressure perception, VO2max and body temperature were examined with specialized tools. Variations in independent variable related to intervention were analyzed using t test in the significance level of P<0/05 and SPSS software.
Results: Physiological responses of blood lactate (p = 0.002), heart rate (p = 0.01), ratings of perceived exertion (p = 0.002), time to exhaustion (p = 0.001), blood pressure (p = 0.01) =) and body temperature (p = 0.002), after deprivation of sleep to a debilitating activity in the post-test compared to the pre-test increased and the maximum oxygen consumption (p = 0.001) decreased significantly, which was also statistically significant. The findings of the present study showed that sleep deprivation can cause a significant change in the objective and subjective physiological responses of sports students.
Conclusion: According to the results of the present study, it was found that 30 hours of sleep deprivation caused significant changes in the objective and subjective physiological responses of athlete students. In a general conclusion, the findings of the present study showed that sleep deprivation should be mentioned as one of the potential limiting factors of physiological function.
Vahid Kazemizadeh, Amirabbas Monazzami, Fakhredin Saba, Andrew J McAinch,
Volume 14, Issue 4 (12-2024)
Abstract

Introduction: This study aimed to analyze the effects of endurance training (Aerobic) on the levels of inflammatory markers (IL-6/TNF-α) and some metabolic parameters in male rats with non-alcoholic fatty liver disease to investigate the feasibility of using exercise training to reduce inflammation.
Material and Methods: A total of 44 Wistar rats were randomly assigned into two groups: (I) standard diet group of 22 rats and (II) high-fat diet group with 22 rats supplemented with free access to fructose water. After 17 weeks, two rats from each group were sacrificed, and liver tissue was collected for hematoxylin-eosin staining. Subsequently, the remaining 20 rats in the (I) group were divided into a training group (T) and a control group (C). The 20 rats in the (II) group supplemented with fructose water were divided into a fatty liver group (FL) and a fatty liver + training group (FL+T), each comprising ten rats. In the next phase, the T-groups underwent an eight-week endurance training intervention. Then, IL-6, TNF-α, glucose, insulin, insulin resistance and sensitivity levels were measured.
Results: The results of the present study showed that as a result of a high-fat diet with liquid fructose in HFD+HF group rats, non-alcoholic fatty liver disease (NAFLD) with complications such as a significant increase in the levels of IL-6 and TNF-α, Hepatic dysfunction, and metabolic parameters were disturbed (p<0.001). However, endurance training improved most of these complications by reversing the disease process (p<0.001).
Conclusion: According to the results of the present study, it can be concluded that the improvement of inflammatory markers, liver dysfunction, and metabolic parameters through endurance training is one of the key mechanisms of exercise in the treatment of NAFLD, the consequences of which may show the importance of endurance training in treatment of NAFLD highlights.

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