Journal of Health and Safety at Work

---

Introduction: Construction industry plays a major role in the economic development of all countries and among the various occupations, this industry is one of the most dangerous industries, particularly respiratory contaminants, around the world. The aim of this study was to evaluate the respiratory capacity of construction workers, working in different workshops in Tehran city and developing a regression model to examine the relationship between pulmonary capacities with the type of occupation, work experience and tobacco smoking.
Material and Method: This study was a cross-sectional descriptive study conducted among 628 construction workers in Tehran city in 2017. After data collection, data analyses were performed using statistical independent t-test, one way ANOVA and correlation tests by SPSS software version 22. Also, multiple backward regression was used to check the effect of independent variables on lung function.  
Result: According to the results of this study, a significant relationship was found between age and work history with the pulmonary function indexes (FVC, FEV1, FEV1/FVC and FEF25-75%) (P-value<0.001). The average of FEV1/FVC% was significantly different among various occupational groups (p-value<0.001). In the analysis of the findings of the pulmonary function test in the exposed group a separate model was made using multiple linear regression for each of the pulmonary functions, and the independent variables including age, work experience, job type and cigarette addiction were entered into the model.
Conclusion: The present study showed a significant change in the pulmonary function parameters of the construction workers and the chance of pulmonary disorders might be high among these individuals.

---

Introduction: Nowadays, working in any computer work stations, named visual display terminal (VDT), was widespread and has become popular in our lives. Due to the increasing trend of using computers in the administrative and social institutions, prevalence of eye-related signs of working with computers is still increasing and it is one of the most important health issues. Computer jobs are low-mobility and require little energy to do physical work, but require more cognitive processing and mental focus. Visual fatigue is an occupational hazard for people working with computers. Eye fatigue has symptoms such as headaches, job discomfort, and eye pain the purpose of this study was to have a systematic review on eye fatigue, dry eye and eye blink among people working with visual terminals.  
Material and Methods: Internet search databases and search engines were used to find articles with focusing on the impact of risk factors on eye indexes on computer users. In this study, related articles were obtained from websites, including: PubMed, Google Scholar, Scopus and Web of Sciences. The keywords were used to search in these websites were: computer user, eye fatigue, dry eye and eye blink. Accordingly, after finding 115 relevant articles from the related sites, 17 articles were finally selected.
Results: Findings show that using computer cause many problems in the eye. Duration of using the computer, the type of work with the computer, the mental load, the distance from the monitor, and also long-term use of the computer without break in during work can cause dry and fatigue eye in users, which is one of the most common ocular problems among computer users.
Conclusion: According to the finding and results recommended to reduce of dry and fatigue eye, distance of users from the monitors, be more than 50cm, use 20-20-20 law to rest user’s eyes, and  Positioning the monitor be 15-20 degrees below the user’s line of sight. Also, too much focus on the screen reduces blinking and resulting in dry eyes. In order to prevent dryness of the surface of the eye, it is recommended that the eyelid be optional even if possible. Increasing the contrast of the monitor can be helpful in reducing stress and strain on the eye while working with a computer and using glasses instead of lenses to correct refractive errors and one of the ways to control and improve dry eye is using artificial tears by computer users.

---

Introduction: Chlorpyrifos is an organophosphorus insecticide that can produce reactive oxygen species, and oxidative stress in the kidney. On the other hand, rosemary extract is an antioxidant playing a protective role against free radicals. Therefore, the aim of this study was to evaluate the oxidative stress in rat kidney due to the exposure to chlorpyrifos and to assess the antioxidant effect of two concentrations of 100 and 200 mg / kg rosemary extract on the nephrotoxicity caused by this pesticide.
Material and method: In the current study, 30 male Wistar Rats, weighing 200-220 g were used. They were randomly divided into five groups and selected as the study groups, each group including six rats  for further comparison. They were as following groupd: Group І: served as control (received dissilated water, i.p) , Group П: the chlorpyrifos exposure group (13.5 mg / kg, i.p.), Group Ш: the group exposed  to rosemary extract (100 mg / kg) by gavage, Group ІV: the exposure group with rosemary 100 mg / kg concentration (by gavage) and after 30 minutes exposure to chlorpyrifos (13.5 mg / kg, i.p.) and Group V: simultaneous exposure of rosemary 200 mg / kg concentration (by gavage) and after 30 minutes exposure to chlorpyrifos (13.5 mg / kg, i.p.). After 2 and 4 weeks, the rats were weighed and killed. A section of kidney tissue was examined for changes of Malondialdehyde (MDA) and Glutathione peroxidase (GPx) and another section was tested for histopathological alterations.
Results: The results showed that chlorpyrifos significantly damaged the kidney tissue and altered the activity of GPx and MDA compared to the control group, as well as it damaged the kidney tissue. Moreover, the simultaneous exposure to chlorpyrifos and rosemary extract with concentration of 100 mg/kg significantly made modifications to the MDA and GPx levels. In addition, with the increasing of rosemary doses from 100 to 200 mg / kg, changes in the levels of MDA and GPx were closer to those of the control group.
Conclusion: The rosemary extract can reduce the oxidative stress caused by chlorpyrifos and, therefore, can be used to treat the poisoning caused by this pesticide.

---

Introduction: Errors are a byproduct of human information processing or cognitive functioning. Although everyone is disposed to an error while performing various activities, individual differences in cognitive abilities can lead to various types and rates of errors committed in similar situations. Human errors are one of the most important challenges in work environments, including health care systems, wherein such errors are abundantly occurring. Errors in the delivery of correct medications due to the resemblance in appearance and name are thus one of the cognitive errors that come about in health care systems. The main purpose of this systematic review was to evaluate evidence and approaches recently practiced to reduce medication errors caused by the use of look-alike-sound-alike (LASA) medications.
Material and Methods: The study was conducted on August 30, 2018, through searches in the databases of PubMed and Embase, all available years, using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) instructions. The searches were done in the titles or abstracts of the articles using the intended terms and the Medical Subject Headings (MeSH) index in combination. These studies were selected based on the inclusion and exclusion criteria and then categorized based on the type of interventions and outputs. Finally, the data were analyzed descriptively.
Results: The research designs and methods varied widely among the studies. There were also discrepancies in the number of participants, number of tests, type of medications, and test conditions. The approaches examined in these studies were tall-man lettering, color-coding, label background variations, and use of signs and symbols. Accordingly, 11 studies had utilized tall-man lettering and the most important reported in all articles were “error rate” and “response times”. As well, a wide range of medication names had been tested. It should be noted that medication
Conclusion: errors have different dimensions, but the errors caused by the look-alike-sound-alike (LASA) medications and the effect of tall-man lettering of medication name were only investigated in the present study. Laboratory studies in this respect have shown that tall-man lettering contributes to mitigating the rate of errors, which might be due to the better legibility of labels, but evaluations in real work environments are needed to reinforce this conclusion. There is also insufficient evidence to support color-coding, as well as several other approaches such as use of signs and symbols. Because of the novelty of the studies in this field, no uniform mechanism has been so far introduced.

---

Introduction: The respiratory system, one of the most important organs of the body, can be affected by adverse effects, disorders and consequences in the workplace. Spirometry is one of the most important screening and testing tools in the periodic medical examination of every employee. This study was aimed to evaluate the factors affecting the respiratory function of staff of Tehran University of Medical Sciences (TUMS).
Material and Methods: This descriptive-analytical and cross-sectional study carried out on 300 employees of TUMS according on during the enrollment phase of the Tehran University of Medical Sciences employee’s cohort (TEC) study was in order to survey the parameters affecting pulmonary function. Demographic data were collected through a demographic questionnaire. Spirometry was used to evaluate respiratory function parameters and bioelectric impedance was used to analyze body composition. Data analysis was performed by SPSS software version 25. Two-sample t-test, one-way ANOVA, and Pearson correlation coefficient were used for statistical analysis. Multiple linear regression was used to determine the effect of independent variables on the parameters of pulmonary function.
Results: It was found that 73.6% of the subjects had a normal lung pattern, 7% had an obstructive pattern, 14.7% had a threatening pattern and 4.7% had a mixed pattern. There was a significant negative correlation between FVC and FEV1 parameters and smoking (P-value <0.05). There was also a significant relationship between FFM, age and BMI with FEV1/FVC (P-value <0.05). Similarly, there was a meaningful relationship between type of job and FVC parameter (P-value <0.05). The findings showed that the highest and the lowest averages of all parameters of pulmonary function was in administrative and occupational services, public and technical services and facilities, security and guard, respectively.
Conclusion: In the present study, it was found that occupation type affects lung function due to exposure to contaminants in different groups. Other factors affecting lung function included age, body mass index, fat mass, fat free mass and smoking. Therefore, changing lifestyle such as proper diet, regular exercise and not smoking can be an effective step towards improving the parameters of lung function.

---

Introduction: Nowadays, excessive computer use in the workplace has raised concerns about the health status of VDT workers, particularly complaints about eye discomforts. Due to the importance of the eyelids and eye closure parameters on eye health during computer works and the direct effect of monitor height on these parameters, this study was aimed to examine the effect of different monitor heights adjustment on the eye indicators and eye discomfort among participants.
Material and Methods: In this study, any changes in the eye indicators including blink rate, the eye blink opening and closing time, the blink opening rate in three different monitor heights (standard, low, and high) were examined among 11 participants. The blink rate and the eye blink opening and closing time were measured and evaluated using videotaping and analyzing by an image processing software, developed in this study. Participants were also asked to complete a questionnaire for eye fatigue assessment due to daily computer uses.
Results: Results showed that the highest rate of eye blink was at the standard height of the monitor, and this rate was significantly different at three different heights of monitors (high, standard, and low) (p<0.05). The lowest blink rate was observed at low and high heights with an average of 7.3 and 7.8 and the highest blink rate at standard height with an average of 8.9 blink per minute, respectively. Meanwhile, image processing and analyzing of eye surface showed, in average, 16% decrease in the opening rate of the eye surface by decreasing the height of the monitor, and 15% increase by increasing it, relative to the standard mode of monitor.
Conclusion: To protect users from computer-related eye strain, it is recommended to correct monitors height to the standard height along with typing and data entry training for keyboarding skill development and minimizing working times as a result. What is more, a proper work-rest schedule when working with computer can be considered as an effective countermeasure to prevent from eye strain.