Journal of Health and Safety at Work

---

Introduction: 1,3-Butadiene is a carcinogenic compound that can be emitted to the atmosphere from several sources like petrochemical industry. One way to determine the level of carcinogenic and health effects of respiratory exposure to pollutants in the workplace is to use risk assessment methods. The aim of this study was to comparative assessment of carcinogenic risk of respiratory exposure to 1,3-Butadiene in a petrochemical industry by the US Environmental Protection Agency and Singapore Health Department methods.
Material and method:  This cross-sectional study was carried out in 2018 in a petrochemical industry that producing copolymer ABS (acrylonitrile, butadiene, styrene) in Iran. Occupational exposure to 1,3-Butadiene was measured according to the NIOSH 1024 method. Cancer risk assessment was done according to the United States Environmental Protection Agency (USEPA) and Singapore semi-quantitative methods.
Results: The average occupational exposure to 1,3-Butadiene during work shift among all participants was 560.82 ± 811.36 µg.m^-3 (0.253 ± 0.367 ppm) and in all cases was below the occupational exposure limit. The average lifetime cancer risk in USEPA method in the present study was 2.71 × 10^-3, Also in this method 82.2% of all exposed workers were in the definite carcinogenic risk level and 17.8% were in the probable carcinogenic risk level. The results of the Singapore health department method showed that 91.2% of all subjects were in the probable carcinogenic risk level and 8.8% were in the definite risk level.
Conclusion: The findings of the present study showed that the results of the Singapore semi quantitative risk assessment method are not in good agreement with the results of the quantitative risk assessment method proposed by the US Environmental Protection Agency. Therefore, given the high accuracy and thoroughness of the US Environmental Protection Agency's risk assessment methodology as a worldwide reference method for assessing the carcinogenic and health risk of exposure to chemicals, it is recommended to use this method instead of the Singapore method in future studies.

---

Introduction: Styrene (C₆H₅CH=CH₂) is known as one of the volatile organic substances produced or used in petrochemical industries. Exposure to this chemical compound can thus lead to respiratory diseases. Therefore, this study aimed to evaluate occupational exposure to styrene vapor and to determine the risks of its health consequences in petrochemical industry workers through a quantitative method.
Material and Methods: In this descriptive cross-sectional study, a total number of 150 samples from 50 employees were studied using the National Institute for Occupational Safety and Health (NIOSH) 1501 method. The samples were then analyzed by the Varian CP-3800 chromatograph. Upon determining exposure to styrene vapor, the risk assessment of the health consequences of styrene in the workers in the given industry was evaluated via the relationships established by the United States Environmental Protection Agency (US/EPA).
Results: According to the results, the polybutadiene latex unit (PBL) was observed with the highest average exposure (0.44 mg.(kg-day)-1). Therefore, the top predictors of carcinogenic and non-carcinogenic risks were valued 0.44 and 0.71, respectively, for the PBL unit. Given the lowest average exposure (0.0012 mg.(kg-day)-1) in the drying unit, the prediction revealed the most moderate carcinogenic (0.1 ×10-5) and non-carcinogenic risks (2×10-3) for the same employees.
Conclusion: Overall, the health risk was higher than the permissible limit in the petrochemical industry studied, especially in the PBL unit. Therefore, it is recommended to make use of artificial ventilation, notably the local type, in addition to the natural ones.

---

Introduction: The respiratory system, one of the most important organs of the body, can be affected by adverse effects, disorders and consequences in the workplace. Spirometry is one of the most important screening and testing tools in the periodic medical examination of every employee. This study was aimed to evaluate the factors affecting the respiratory function of staff of Tehran University of Medical Sciences (TUMS).
Material and Methods: This descriptive-analytical and cross-sectional study carried out on 300 employees of TUMS according on during the enrollment phase of the Tehran University of Medical Sciences employee’s cohort (TEC) study was in order to survey the parameters affecting pulmonary function. Demographic data were collected through a demographic questionnaire. Spirometry was used to evaluate respiratory function parameters and bioelectric impedance was used to analyze body composition. Data analysis was performed by SPSS software version 25. Two-sample t-test, one-way ANOVA, and Pearson correlation coefficient were used for statistical analysis. Multiple linear regression was used to determine the effect of independent variables on the parameters of pulmonary function.
Results: It was found that 73.6% of the subjects had a normal lung pattern, 7% had an obstructive pattern, 14.7% had a threatening pattern and 4.7% had a mixed pattern. There was a significant negative correlation between FVC and FEV1 parameters and smoking (P-value <0.05). There was also a significant relationship between FFM, age and BMI with FEV1/FVC (P-value <0.05). Similarly, there was a meaningful relationship between type of job and FVC parameter (P-value <0.05). The findings showed that the highest and the lowest averages of all parameters of pulmonary function was in administrative and occupational services, public and technical services and facilities, security and guard, respectively.
Conclusion: In the present study, it was found that occupation type affects lung function due to exposure to contaminants in different groups. Other factors affecting lung function included age, body mass index, fat mass, fat free mass and smoking. Therefore, changing lifestyle such as proper diet, regular exercise and not smoking can be an effective step towards improving the parameters of lung function.

---

Introduction: One of the most important factors affecting quality of work-life (QWL) is the workload in the form of mental and physical. The increased workload may reduce the level of performance of workers. Therefore, the present study aimed to evaluate the relation of the mental and physicalworkload with the QWLof workers in the foundry industry.
Material and Methods: This cross-sectional study was conducted on 218 male workers in a foundry industry and the work units with high work stress were selected. The NASA-TLX, physical load and the Walton questionnaires were used to collect and evaluate the workload and the QWL.The SPSS software was used for data analysis.
Results: It was clarified that there was a significant inverse relationship between QWL with physical load (P = 0.001) and mental workload (P = 0.01). The comparison of mean QWL between different groups of demographic variables showed that the only significant relationship was between different age groups and QWL (P = 0.003). Finally, it was found that the variables of physical load, mental workload and age had a significant simultaneous effect on the mean score of QWL (P<0.05).
Conclusion: The findings showed that there was a significant relationship between QWL and mental and physical workloads.