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Showing 2 results for kiani

F. Kiani, M. R. Khodabakhsh,
Volume 3, Issue 3 (12-2013)
Abstract

Introduction: Researches show that workplace quality play important role in developing job involvement. The purpose of this study was to determine the predicted power of job involvement by perceived supervisor support and perceived coworker support.

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Material and Method: This research was a cross-sectional study. The participants consisted of 189 employees from Isfahan Steel Company in 2012 and they were selected according to the stratified random sampling method and responded questionnaires about demographic characteristics, perceived supervisor support, perceived coworker support and job involvement. Data was analyzed using Pearson correlation coefficient and regression analysis.

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Result: The results showed that there were significant relationships between perceived supervisor support and perceived coworker support with job involvement (p<0.05). Also, results indicated that the variables of perceived supervisor support and perceived coworker support significantly predicted almost 13% and 11% of job involvement variance (p<0.05).

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Conclusion: The research results maintain the importance of psycho-social variables in predicting job involvement in workers.


Esmaeil Karami, Zahra Goodarzi, Reza Chahardoli, Mahmoud Ghazi Khansari, Mehrafarin Kiani, Seyed Jamaleddin Shahtaheri,
Volume 12, Issue 2 (6-2022)
Abstract

Introduction: Although aluminum oxide nanoparticles (Al2O3-NPs) are the most widely used nanomaterials, limited studies have been reported on their toxicology. Therefore, the present study aimed to investigate the potential toxicity of aluminum oxide (alumina) nanoparticles and the protective role of aqueous extract of wormwood plant on nanomaterial-induced disorders in the lung of rats.
Material and Methods: Here, 36 male Wistar rats were randomly divided into six groups. Next, the rats were first exposed to 200 mg/kg of the aqueous extract of wormwood plant (by gavage) for 15 days and then received a dose of 30 mg/kg of aluminum oxide nanoparticles as an intraperitoneal injection for 14 days. Furthermore, various features of clinical signs, body weight, biochemical parameters, gene expression changes, lung weight ratio, histopathological observations, and metal content in lung tissue were evaluated during the experiment. Eventually, the ANOVA (Analysis of Variance) and Tukey’s range test were employed to analyze and compare the mean of the data.
Results: The results revealed that aluminum oxide nanoparticles at a concentration of 30 mg/kg body weight led to changes in antioxidant enzyme activities, e.g., T-SOD, CAT, GPx, and TAC, lipid peroxidation, and iNOS for exposed rats. Also, the above biochemical disorders were associated with altered expression of oxidative stress-related genes (HO-1, MT-1) and histological changes in the lung tissue. On the other hand, simultaneous intake of aqueous extract of wormwood plant and aluminum oxide nanoparticles in rats significantly improved the studied parameters (p <0.05).
Conclusion: Our findings showed that the γ-Al2O3 NPs were more toxic than α-Al2O3 NPs, which can be attributed to changes related to their size and shape characteristics. Also, it was observed that the wormwood plant could play a protective role against aluminum oxide nanoparticles-induced pulmonary toxicity in rats.


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