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Showing 23 results for Exposure

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Volume 1, Issue 2 (3-2012)
Abstract

Introduction: Needlestick (NSI) is a known serious treat and occupational exposure among health care workers especially nurses. Since nurses are the biggest part of healthcare workers, and considerable percent of NSI are preventable, we decided to determine frequency of NSI and some related occupational factors among a group of them.

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Methods and Materials: This cross-sectional project was conducted among all the nurses (340 nurses with at least one year work experience) in Babol and Amirkola educational and private hospitals (in north of Iran). The data were gathered by means of a tailor-made data collection sheet including personal information and some occupational effective factors, during autumn and winter. The data were analyzed with descriptive statistical indexes and Chi-square test.

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Results: Our result showed that the relative frequency of NSI among the nurses group (the mean age of nurses was 33.8±7.7 years old and the mean work experience was 10.3±8 years) was 59.7 percent. Chi-square test result indicated that there were significant differences between NSI in different groups of some personal and occupational factors including age, years of experience, training condition, and needle recapping(p<0.05).

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Conclusion: According to positive effects of training and negative effects of incorrect working habits, repetition and completion of occupational education is necessary.


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Volume 2, Issue 2 (9-2012)
Abstract

Introduction: Application of agricultural machineries such as tractor has been yielded a considerable development in different agricultural activities and productions. However, noticeable health problems such as noise pollution impact the users of these off-road vehicles. The purpose of this study was to determine the noise level induced by agricultural tractors and to evaluate the driver’s noise exposure level.

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Material and Method: The sound pressure levels of three brands of tractor include John Deere, Ferguson and Romani were measured by sound level meter model Tes-1358. The characteristics of place for measuring tractors noise pollution were determined based on the ISO standard No 7216, 5131. The acquired data was analyzed using spss16 software.

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Result: The results showed that the highest and the lowest noise level around the tractors were 83.8 dB (A) and 73.9 dB (A) for the John Deere and Romani, respectively. The effect of different transmission gears on the noise level of tractors was not statistically significant Pvalue>0.05. While, the effect of the tractor engine speeds on the noise level was statistically significant Pvalue<0.01. The exposure time of the most of drivers was frequently about 8 hour or more In this regards, the exposure levels of the tractor’s drivers to noise measured between 85-90 dB (A) were higher than the Iranian occupational exposure limit (85 dB (A)).Moreover, mean noise reduction rate of exsisting room which was used upon the typical tractor’s body was 9.5 dB in one octave band.

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Conclusion: Application of standard cockpit and expansion mufflers can effectively reduce noise pollution emission and driver’s occupational exposure. Moreover, regular preventive maintenance and effective hearing conservation program including annual audiometry, hearing protection device, occupational health training for drivers must be implemented.


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Volume 2, Issue 2 (9-2012)
Abstract

Introduction: According to the literature, a large number of people working in industries and service providing personnel, such as firefighters, physicians, and nurses, are shift workers. The spread of shift working in industrial societies and the incidence of the problems resulting from shift working have caused the researchers to conduct studies on this issue. The present study also aimed to investigate melatonin and cortisol circadian rhythms in the security guards of Shiraz University of Medical Sciences, Shiraz, Iran.

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Material and Method: The present study was conducted among 20 security guards of Shiraz University of Medical Sciences. In order to collect the required data, blood samples were taken from the participants in different times of the day (1, 4, 7, 10, 13, 16, 19, and 22) and cortisol and melatonin levels were determined using radioimmunoassay and enzyme immunoassay techniques, respectively. Then, the data were entered into the SPSS statistical software (v. 16.0) and analyzed using One-Way ANOVA.

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Result: The results showed that as the intensity of light increased during night time, the level of plasma cortisol increased, as well. Besides, no statistically significant difference was found between the plasma cortisol levels in natural light and 4500-lux light. On the other hand, a significant difference was observed between the level of plasma cortisol in natural light and 9000-lux light as well as 4500- and 9000-lux lights. The study findings also showed that as the intensity of light increased at night, the level of plasma melatonin decreased. In addition, a statistically significant difference was found between the plasma melatonin levels in natural light and 4500-lux light. Nevertheless, no significant difference was observed between the plasma melatonin levels in natural light and 9000-lux light as well as 4500- and 9000-lux lights.

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Conclusion: The present study aimed to investigate the subsequences of shift working in the security guards of Shiraz University of Medical Sciences and showed that occupational exposure to bright light could affect some biological markers, such as melatonin and cortisol secretion.


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Volume 2, Issue 4 (2-2013)
Abstract

Introduction: Existing literatures indicate that occupational exposure to formaldehyde may decrease blood platelets. In this study, the influences of occupational exposure to formaldehyde on the number of blood plateletsand clinical symptoms were studied while determining the occupational exposure of employees of a wood industry to formaldehyde.

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Material and Method: In a case study, the occupational exposure to formaldehyde was determined among 30 workers from production line and 30 administrative staffs of a wood company using US-NIOSH method No 2541. The number of blood platelets was determined using the normal blood count method and related indices. Demographic data as well as the clinical symptoms of exposure to formaldehyde were collected using a standard questionnaire. The smokers and those using drugs interacting with similar symptoms and blood characteristics were excluded from the study. Ethical principles for medical research involving human subjects announced in Helsinki declaration were considered. The research proposal had been approved by the university committee of ethics prior to its execution. Details of tests were explained for all subjects and a written consent was signed by each subject.

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Result: Occupational exposure of workers in various parts of particle board production line ranged from 0.5 ppm to 1.52 ppm which was higher than the ceiling level (0.3 ppm) recommended by US-ACGIH. The prevalence of all studied symptoms from formaldehyde exposure in workers was significantly higher than the administrative staffs. In case group, tearing rate was the highest average 8.98 while the chest pain with an average rate of 3.20 was the lowest. In control group, the prevalence of coughing with an average rate of 6.62 was the highest and the chest pain with an average rate of 5.53 was the lowest. The average number and standard deviation of blood platelets of workers in production line and staffs were statistically different with the range 207.33±41.79 and 254.60±71.05, respectively. The statistical tests showed no relationship between the level of occupational exposure to formaldehyde and the number of blood platelets (p>0.05). This means that, increasing the exposure level would not lead to a further reduction in the number of platelets.

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Conclusion: Occupational exposure to formaldehyde significantly changed the number of blood platelets.


, , , , , , ,
Volume 2, Issue 4 (2-2013)
Abstract

Introduction: Noise exposure is known as a risk factor for hearing loss and one of its effects is noise-induced stress. Cortisol, as stress hormone- is used in noise-induced stress assessments studies. The aims of this study were:(1) measuring and comparing saliva cortisol concentrations in the morning and evening in normal work day and rest day between two groups, (2) assessing the relationship between industrial noise exposure and salivary cortisol concentrations between two groups.

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Material and Method: Two hundred male workers (100 industrial and 100 office employees) participated in this study. Morning and evening saliva samples were collected at 7 a.m and 4 p.m, respectively. Noise exposure levels were assessed by sound level meter and noise dosimeter. All measurements occurred in two days: one in rest day and other in working day. Descriptive statistics, paired and independent sample t-test and regression analysis were used as statistical tools with α=0.05.

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Result: On the rest day and work day, between morning salivary cortisol was no significant difference in two groups. Comparing evening cortisol concentrations in work day with rest day a significant difference was observed, in worker group, but it was not significant in the other group. The evening cortisol in the working day in was significantly higher among workers than officers.

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Conclusion: This study revealed that industrial noise exposure with levels higher than 80 dBA has a significant effect on salivary cortisol elevation.


H. Aghaei, H. Kakooei, S.j. Shahtaheri, F. Omidi, S. Arefian, K. Azam,
Volume 3, Issue 4 (2-2014)
Abstract

Introduction: PAHs are organic compounds with benzenic rings that releas from hot asphalt as incomplete combusting. These compounds are one of the major concern in scientific societies, workplace and environment due to their stability, bioaccumulation, carcinogenic and mutagenic effects. Since asphalt workers are exposed to PAHs frequently in their job, in this study it was attempted to evaluate respiratory exposure of asphalt workers to PAHs in their breathing zone.

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Material and Method: In this study air samples of the asphalt workers were collected in accordance with the NIOSH 5506 method using PTFE filter and XAD-2 adsorbent. The ultrasonic bath and acetonithrile are used in order to extract the analytes from the filter and adsorbent. Also, the samples were analyzed by HPLC-UV.

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Result: In all samples, Finisher assistance and oilman with 1754.48 ng/m3 , 24.65 ng/m3 had maximum and minimum exposed to ∑PAH, respectively. Among the PAHs compounds, which asphalt workers exposed to, Naphtalene had the highest concentration. Among different asphalt workers tasks, screedman expoused to PAHs, had a significant difference.

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Conclusion: Evaluation of Polycyclic aromatic hydrocarbons concentrations in the breathing zone of asphalt workers indicated that exposure to these compounds were below the occupational exposure limits recommended by NIOSH, OSAH, ACGIH and Iranian OEL. Due to the highly carcinogenic potential of some of these compounds and absence of occupational exposure limits for these compounds, likes Chrysene and Benzo (a) Anthracene, it is strictly recommended to employ engineering controls and using suitable PPEs. This study also indicated that the exposure to PAHs in the most asphalt workers tasks had significant differences, and it can be due to proximity of the workers to the source of hot asphalt and also exposure to the exhaust gases that releasesd from the construction machinery.


M. Abbasi, M. R. Monazzam Esmaielpour, A. Akbarzadeh, S. A. Zakerian, M. H. Ebrahimi,
Volume 5, Issue 3 (9-2015)
Abstract

Introduction: Installation of wind turbines in residential areas due to their unique sound characteristics may cause noise annoyance. Noise annoyance can increase the risk of health problems and sleep disturbance. Thus, this study was conducted to assess the effect of wind turbine noise annoyance on sleep disturbance among the Manjil wind farm workers.

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Material and Method: All the Manjil wind farm workers have been divided into three groups according to their noise exposure levels, including maintenance, security, and administrative workers. The equivalent A weighted noise levels were measured for each of the study working groups, using ISO 9612 standard method. Information related to the noise annoyance and sleep disturbance were determined by ISO15666 standard and the Epworth Sleepiness Scale, respectively. Data were analyzed using R software.

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Result: Findings of ANOVA and Kruskal-Wallis statistical tests showed that noise annoyance and sleep disturbance were statistically different among workers with various occupational, age, and work experience groups. Also, noise annoyance and sleep disturbance had a significant association in a way that regardless of the effects of other variables, it can be stated that for every one unit increase in noise annoyance, 0.26 units will be added to the amount of sleep disturbance.

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Conclusion: In this study, workers with more wind turbine noise annoyance had more sleep disturbance. Therefore, in addition to the direct effects of noise on sleep disturbance, it can indirectly exacerbate sleep disturbances.


Kourosh Sayehmiri , Marzieh Beigom Bigdeli Shamloo, Marzieh Khataee, Forghan Rabiei Fakhr, Milad Azami,
Volume 6, Issue 3 (9-2016)
Abstract

Introduction: Lead exposure is considered as a global health problem. The irreparable harmful effects of this heavy metal on human have been proven in various studies. Comparing to general population, workers in related industries are more exposed to lead. Several studies have investigated lead occupational exposure and its biological evaluation in Iran; however there is no overall estimate. Thus, the present study was conducted to determine the occupational exposure to lead and its biological evaluation in Iranian workers, using systematic review and meta-analysis.

Material and Method: This study was carried out based on information obtained from databases including Magiran, Iranmedex, SID, Medlib, Trials Register, Scopus, Pubmed, Science Direct, Cochran, Embase, Medline, Web of Science, Springer, Online Library Wiley, and Google Scholar from 1991 to 2016, using standard key words. All of the reviewed papers which met the inclusion criteria have been evaluated. Data combination was performed according to Random Effects Model using Stata software version 11.1.

Result: In the 34 qualified studies, the mean blood lead level (BLL) concentration in Iranian workers was estimated 42.8µg/dl (95% CI: 35.15-50.49). The minimum and maximum BLL were belonged to west (28.348µg/dl) and center (45.928µg/dl) regions of Iran, respectively. Considering different occupations, the lowest mean value was reported in textile industry workers (12.3 µg/dl), while the highest value was for zinc-lead mine workers (72.6 µg/dl). Mean breathing air lead level of Iranian workers reported in 4 studies was estimated 0.23 mg/m3 (95% CI: 0.14-0.33).

Conclusion: According to the high concentration of BLL and breathing air, it is recommended to increase protective measures and frequent screening. Scheduled clinical and paraclinical examination should also be performed for workers.


Keykaous Azrah, Mohsen Poursadeghiyan, Mohammad Javad Fani , Mohammad Rezazade, Ardalan Solaimanian,
Volume 6, Issue 3 (9-2016)
Abstract

Introduction: Limited studies have been done to evaluate the whole-body vibration (WBV) exposure experienced by Taxi drivers. Therefore, the aim of this study was to evaluate the exposure to whole body vibration and repeated shocks in urban taxi drivers and also to compare different methods of evaluation in this job environment.

Material and Method: Measurement and evaluation process were conducted in accordance with procedure of the ISO 2631-1 and ISO 2631-5 standards. The measurements were done by SVAN 958 Sound and Vibration Analyzer and using tri-axial accelerometer centered on the contact surface between the seat and the driver in 9 taxis.  

Result: The measurements done according to ISO 2631-1 method showed greater risk compared to Daily Equivalent Static Compression Dose, Sed, presented in ISO 2631-5. Calculated daily exposure durations for exposure action level in root-mean square, vibration dose value, and daily equivalent static compressive stress methods were 4.55, 3.54 and 31.70 hours, respectively.

Conclusion: The large differences in estimated exposure durations of action limits and permissible limits resulted by different methods reflect the inconsistency of the selected evaluation methods. Therefore, future research is necessary to amend the limits presented in the standard.


Javad Sajedifar, Amir Hosein Kokabi, Kamal Azam, Somayeh Farhang Dehghan, Ali Karimi, Farideh Golbabaei,
Volume 6, Issue 4 (12-2016)
Abstract

Introduction: Nowadays, Shielded Metal Arc Welding (SMAW) is the most widely used arc welding. During the welding operation, typically, various harmful agents such as fumes, gases, heat, sound and ultraviolet radiation are produced of which fume is the most important component from the viewpoint of occupational health. The present study aims to compare the number and the mass concentration emitted in SMAW to determine the most appropriate index of exposure to fumes in the welding processes.

Material and Method: In this study, the portable laser aerosol spectrometer and dust monitor of GRIMM, model 1.106, was used to measure the number and mass concentration of fumes emitted from SMAW on 304 stainless steel with a thickness of 0.4 mm. Air sampling was performed at a distance of 41 cm representing the welder’s breathing zone. The measurements of number concentration (NC) and mass concentration (MC) were taken under the condition of 25 volt voltage and direct current of the electrode polarity.

Result: The total NC and MC of welding fumes in welder’s breathing zone was 1140451 particles per liter and 1631.11 micrograms per cubic meter, respectively. The highest number concentration was found to correspond to the particles with 0.35 to 0.5 micrometer-sized distribution (NC1; 938976 particles per liter) and the lowest was related to the particles with 5 to 6.5 micrometer-sized distribution (NC7; 288 particles per liter) and the particles larger than 6.5 micrometer (NC8; 463 particles per liter). Moreover, the highest mass concentration was related to the particles with 0.35 to 0.5 micrometer-sized distribution (MC1; 450 micrograms per cubic meter) and the particles larger than 6.5 micrometer (MC8; 355 micrograms per cubic meter).

Conclusion: The findings indicated that there is no agreement between number and mass concentration as two particles assessment index, and as the particles’ size become smaller, the mismatch of them is becoming more apparent. Since the smaller particles penetrate into the lower respiratory tract and have higher potential for adverse health effects, it is necessary to measure and assess particles in various size distributions and especially the smaller fraction of particles. Therefore, it is thought that considering the mass concentration alone and not paying attention to number concentration in the assessment of exposure to particles in the industrial workplaces and specifically in welding stations will not be reflected valid assessment of adverse health effects of welding fumes as a systemic poison on body organs.


Fatemeh Zarei, Mansour R. Azari, Sousan Salehpour, Soheila Khodakarim, Saba Kalantary, Elahe Tavakol,
Volume 7, Issue 1 (4-2017)
Abstract

Introduction: Occupational exposure to crystalline silica increases the risk of lung cancer and restrictive lung disease with extensive fibrosis. Silica dust is a major health hazard in foundry factories. The aim of this study was to determine core making workers’ exposure to respirable crystalline silica dust in a foundry factory.

Material and Method: This cross-sectional study was conducted in core-making unit of a foundry factory in 2015. Occupational exposure of 55 workers to respirable crystalline silica aerosols was evaluated by using the improved NIOSH7602 method in core-making unit. Risk assessments for silicosis and excess lifetime risk of mortality from lung cancer were done according to Manettej and Rice models, respectively. Data was analyzed with Spss19 software.

Result: The mean of respirable crystalline silica dust was 0.246 ± 0.351 (mg/m3). All  workers’ exposure to respirable crystalline silica was higher than recommended occupational exposure limits. Silicosis mortality risk and excess lifetime risk of mortality from lung cancer were estimated in the range of 6-63 and 65 per thousand people, respectively.

Conclusion: The mean of workers’ exposure to respirable crystalline silica was higher than recommended occupational exposure standards in core making unit. The risk assessment of silicosis mortality and excess lifetime risk of mortality from lung cancer were higher than acceptable levels of risk.


Hamzeh Mohammadi, Farideh Golbabaei, Somayeh Farhang Dehghan, Mohammad Normohammadi,
Volume 7, Issue 1 (4-2017)
Abstract

Introduction: Exposure to crystalline silica dust can seriously threaten health of workers engaged in processes such as casting, stone crushing, grinding, construction activities, insulator manufacturing, and glassblowing and sandblasting. The aim of this study was to assess occupational exposure to crystalline silica and to determine the risk of mortality from silicosis and lung cancer in an insulator manufacturer.

Material and Method: Air personal sampling was performed using 10 mm nylon cyclone and mixed cellulose ester (MCE) membrane filters (5 mm diameter, 0.8 μm pore size) for 60 male workers. Samples were prepared and analyzed according to the National Institute for Occupational Safety and Health (NIOSH) 7601 standard method. The risk assessment of mortality due to silicosis resulting from crystalline silica exposure was done by using model of Mannetje et al. for the period of 10 years. The mortality rate of lung cancer was determined using a linear regression model derived from the study Rice et al.  

Result: The highest and lowest exposure levels to silica were belonged to the packing unit (0.54±0.28 mg/m3) and the furnace (0.02±0.01 mg/m3), respectively. Crystalline silica concentrations for all samples were higher than Threshold Limit Values (0.025 mg/m3) recommended by the American Conference of Governmental Industrial Hygienists (ACGIH). According to Mannetje et al. model, the cumulative exposure of 25% workers was in the range 0 to 0.99 that it represents 1 death per 1,000 people. The risk of mortality due to lung cancer was obtained in the range of 7-94 persons per 1000 workers exposed to silica.

Conclusion: In general, the geometric and arithmetic mean of crystalline silica exposure was higher than threshold limit value for most of the subjects. For all workers of the insulator manufacturer, the risk of silicosis related mortality was higher than 1/1,000 (unacceptable level of risk). Predicting the lung cancer mortality from silica exposure indicated a high level of mortality risk among understudied workers.


Mohammad Hamid Ijazi, Sara Salarian, Majid Bagheri Hosseinabadi,
Volume 8, Issue 2 (6-2018)
Abstract

Introduction: Mercury, in different form can induce adverse effects on various organs especially central nervous system. The aim of this study was to determine concentration of mercury in inhalation and urine of the exposed worker and to investigate the prevalence of probable neurobehavioral disorders.
 

Material and Method: The present case-control study was conducted among workers of a unit in a petroleum industry. The study population consisted of 52 workers as case and 63 workers as control groups. The mercury concentration in air and urine was measured according to NIOSH 6009 standard and using the cold vapor atomic absorption spectrophotometer (CV-AAS). Demographic data and neurobehavioral disorders were collected using a self-reported questionnaire. Pearson correlation coefficient, multiple regression tests and SPSS v24 were used to analyze the data.
 

Result:  Air concentration of mercury was 0.062 ± 0.0014 mg/m3  which was higher than the recommended threshold by NIOSH and ACGIH. In addition, there was a significant difference between urinary concentration of mercury in the case (37.73 ± 13.01 µg/g cratinine) and control (5.93 ± 4.76 µg/g cratinine) groups (p=0.03 6). Based on the multivariate logistic regression model, significant relationships were found between memory loss, sleep disturbance, and urine mercurial concentrations and, between memory loss, moody, muscle weakness and air mercurial concentration.
 

Conclusion: The values of Hg in blood and urine workers who worked in investigated unit were significantly higher than recommended threshold values. In addition, the Hg concentration in urine was related to some of neurobehavioral disorders.


Milad Abbasi, Parvin Nassiri, Roghay’eh Jaffari Talaar Poshti, Seyed Mohammadreza Taghavi , Saeid Aarabi, Rohollah Fallah Madvari, Mohammad Hossein Ebrahimi, Maryam Ghaljahi,
Volume 8, Issue 3 (9-2018)
Abstract

Introduction: Chronic occupational noise exposure may constitute a risk factor for cardiovascular disease for workers. The aim of this study was to investigate the relationship between occupational noise exposure and noise annoyance with blood pressure, serum cholesterol and triglyceride levels in workers of a textile industry.

Material and Method: This cross-sectional study was carried out among 220 employees of Savadkouh textile industry complex in Mazandaran province, Iran in 2017. To achieve the study objectives, the 8 -hour equivalent sound exposure level was measured and the cumulative noise exposure was calculated. Based on noise exposure level, workers were divided into control and case groups. Then, blood pressure was measured and blood samples were collected from each individual for determination of the serum cholesterol and triglyceride levels and they were transfered to the laboratory for further analysis. The noise annoyance scale and socio-demographic questionnaire were used to collect noise annoyance and other background and demographic information, respectively. Finally, Paired t-test, one-way ANOVA and multivariate regression were used to study the relationship between variables using SPSS Version 20.

Result: In total, 159 workers participated in this study considering the inclusion and exclusion criteria. Eighty-three participants were exposed to more than or equal to 85 dBA, and 76 person were exposed to less than 85 dBA noise level, respectively. The results showed that mean blood pressure and cholesterol were significantly different between the control and case groups (P-value< 0.05). Based on multivariate regression results, noise exposure, cumulative noise exposure (CNE) and noise annoyance had a significant effect on blood pressure (P-value< 0.001).  Cholesterol was also significantly affected by noise exposure and noise annoyance (P-value< 0.005).

Conclusion: Based on the results of current study, noise can be considered as a risk factor for cardiovascular disease ampong workers. Actually, high intensity noise affect serum cholesterol and blood pressure directly, and may do indirectly by causing noise annoyance which acts as a mediator. Therefore, it seems necessary to conduct a controlled cohort study to investigating the interactions among whole variables of interest.


Saba Kalantary, Farideh Golbabaei, Saeid Yazdanirad, Somayeh Farhang Dehghan,
Volume 9, Issue 1 (4-2019)
Abstract

Introduction: Nowadays, millions of people are exposed to the dusts in their workplaces. Occupational exposure to dusts is considered as one of the most common and serious occupational hazards to workers’ health. The purpose of this literature review was to review the literature related to the occupational exposure to dusts in Iran published over the past 14 years.  
Material and Methods: In this review, published articles were obtained from Web of Science, PubMed, Google Scholar, Scopus, ScienceDirect, Islamic World Sciences Citation (ISC), Magiran, SID، Iran Medex, and Civilica search engine. The main keywords for search were Occupational Exposure, Lung, Dust, Total Dust, and Respirable Dust. The relevant articles published in Iran over the past 14 years were searched and extracted after checking their relevancy. All articles were classified based on the titles, years of publication, places of publication, type of industries, geographic distributions, sampling and analysis methods, fields of study, and the amounts of exposure.
Results: Findings showed that in spite of increases in the rate of published literature in recent years and by considering geographical variation and the large number of dust generating firms and industries, a relatively small number of studies was conducted and published in this field. Majority of the studies in this field considered the levels of dust exposure and respiratory effects of dust exposures.  In most studies the levels of occupational exposure to dusts (and crystalline silica dusts) were higher than the recommended limit values.
Conclusion: Although an increasing number of studies can be seen in recent years on occupational exposure to dusts and their effect, by considering the presence of large and small size industries with dust generating pollution  in Iran, the large number of exposed people, adverse-health  effects,  and  the need for control measures, few studies have been published in this field and further works need to be done in this area.
Hassan Rajabi-Vardanjani, Hassan Asilian-Mahabadi, Morteza Bayareh, Morteza Sedehi,
Volume 9, Issue 4 (12-2019)
Abstract

Introduction: Usually, in the toxicological studies of airborne particulate pollutants, inhalation exposure chambers are used for providing and distributing the test atmosphere uniformly and stability in the respiratory zone of laboratory animals. The purpose of this study was to design, evaluate and optimize a whole-body exposure chamber, specifically for small laboratory animals exposed to particulate matter.
Material and Methods: In the first, the papers and scientific resources which had provided the technical details and performance of the inhalation exposure chambers were studied, and the advantages, disadvantages and those factors affecting their performance were extracted. Then the assumptions of the initial design of the chamber were prepared with regard to the principles of fluid dynamics and the standard conditions of lab animal housing. To create a uniform distribution of particles inside the chamber, guide plates of flow were used in the upper cone. Numerical simulation and ANSYS Fluent software were used to optimize the initial design. Drawing geometry of the chambers was done using Design modeler software and meshing of the computational field using ANSYS meshing software. The particles used had a mean aerodynamic diameter of 10 μm, spherical, inert, and a density of 1,400 kg. m^-3 and entered the chamber at the carrier gas velocity. Particle concentration was measured in the chambers along the cylindrical radius at 10 cm intervals on the x-axis. Then the percentage of variation coefficient of the particle concentration for each line was calculated. In the final analysis of the results, the geometry design with the lowest coefficient of variation of particle concentration along the selected sampling line was selected as the best chamber design.
Results: The optimized inhalation chamber has a dynamical flow and consists of a cylinder with two upper and lower cones. The flow enters from the upper cone and after passes through the guide plates, distributes in the interior of the chamber and exits from the lower cone. The k-ε turbulence and Discrete Phase Models could have modeled this problem. Design No. 7 was optimal design with the lowest coefficient of variation of the concentration (4.08%).
Conclusion: The numerical simulation method for planning and optimizing of the chambers, at a much lower cost than the empirical methods, was able to provide comprehensive information on the solution field. The analysis of this information led to the selection of the best chamber design to provide uniform concentration of the particles in the respiratory region of the animals.
Younes Mehrifar, Zohreh Mohebian, Hamideh Bidel,
Volume 10, Issue 2 (5-2020)
Abstract

Introduction: Risk identification and investigation is an appropriate and practical approach for the occupational health professionals. This paper aims to determine exposure to the gases and metal fumes and to perform risk analysis in three common types of welding activities in a shipbuilding industry.
Material and method: This analytical cross-sectional study was conducted in a shipbuilding industry and three types of welding were considered including SMAW, MIG and MAG welding. Sampling of Mn and Cr fumes was carried out using NIOSH 7300 standard method, and NIOSH 6014 method NO2 sampling, and also direct reading devices for CO and O3 gases. Moreover, SQCRA risk assessment method was adopted to specify the level of exposure risk.
Results: The results of risk analysis showed that among gas pollutants, O3 and NO2 in all welding processes had a very high-risk level, while among the metal pollutants; Mn metal showed a high and very high risk level in MIG and SMAW welding.
Conclusion: According to the both sampling results and risk analysis, MIG process welders are more dangerous position than other types of welding.
Vahid Ahmadi Moshiran, Ali Karimi, Farideh Golbabaei, Mohsen Sadeghi Yarandi, Ali Asghar Sajediyan, Aysa Ghasemi Koozekonan,
Volume 10, Issue 4 (11-2020)
Abstract

Introduction: Styrene (C₆H₅CH=CH₂) is known as one of the volatile organic substances produced or used in petrochemical industries. Exposure to this chemical compound can thus lead to respiratory diseases. Therefore, this study aimed to evaluate occupational exposure to styrene vapor and to determine the risks of its health consequences in petrochemical industry workers through a quantitative method.
Material and Methods: In this descriptive cross-sectional study, a total number of 150 samples from 50 employees were studied using the National Institute for Occupational Safety and Health (NIOSH) 1501 method. The samples were then analyzed by the Varian CP-3800 chromatograph. Upon determining exposure to styrene vapor, the risk assessment of the health consequences of styrene in the workers in the given industry was evaluated via the relationships established by the United States Environmental Protection Agency (US/EPA).
Results: According to the results, the polybutadiene latex unit (PBL) was observed with the highest average exposure (0.44 mg.(kg-day)-1). Therefore, the top predictors of carcinogenic and non-carcinogenic risks were valued 0.44 and 0.71, respectively, for the PBL unit. Given the lowest average exposure (0.0012 mg.(kg-day)-1) in the drying unit, the prediction revealed the most moderate carcinogenic (0.1 ×10-5) and non-carcinogenic risks (2×10-3) for the same employees.
Conclusion: Overall, the health risk was higher than the permissible limit in the petrochemical industry studied, especially in the PBL unit. Therefore, it is recommended to make use of artificial ventilation, notably the local type, in addition to the natural ones.
Haniyeh Ekhlas, Hamidreza Pouragha, Mohammadreza Monazzam, Ramin Mehrdad, Parisa Bahrami, Mojgan Zaeimdar,
Volume 11, Issue 4 (12-2021)
Abstract

Introduction: Previous studies have been conducted on the effects of exposure of industrial workers to high levels of noise and their association with mental health or exposure of people to harmful levels of environmental noise. In this study, we investigated the association between moderate noise levels and the symptoms of depression, anxiety, and stress in non-industrial workers.
Material and Methods: This study is a Cross-Sectional study that was conducted using the enrollment phase data of the Tehran University of Medical Sciences Cohort (TEC) study. The study population consisted of 3899 workers of Tehran University of Medical Sciences who were employed in seven occupational groups of the university, Office Workers, Healthcare workers, technical personnel, services workers, security guards, and radiology-radiation units. Exposure to moderate noise level was examined using the Leq10min index, and the Depression Anxiety Stress Scales were examined on the mentioned population by DASS-42 questionnaires.
Results: The results showed that the prevalence of severe to very severe symptoms of depression, anxiety and stress were 8.2, 7.9, and 11% respectively. Also, it was observed that 14.5% of the participants of the study were exposed to noises of more than 70 dB(A). Furthermore, the results indicated that the highest average noise was equal to 71.3 dB(A) for the technical staff group, and the lowest value with an average of 59.1 dB(A) was recorded for the office workers group. The symptoms of severe to very severe depression was associated with exposure to noises above 70 dB(A) (OR:5.22) anxiety (OR:1.16), stress (OR:1.17) and socioeconomic status (OR:1.84). The severe to very severe anxiety was associated with stress (OR: 1.25). On the other hand, the symptoms of severe to very severe stress was associated with variables of age (OR:0.99), gender (OR:0.46), socioeconomic status (OR:1.52), having job management position (OR:0.81) and having healthcare working job (OR:0.65).
Conclusion: Regarding the obtained results of the present study, it was concluded that exposure to moderate noise levels had positive and significant association with depression in non-industrial workers. In non-industrial work environments, exposure to moderate noise levels is and can be independently associated with depression.
Hamzeh Mohammadi, Somayeh Farhang Dehghan, Soheila Khodakarim Ardakani, Farideh Golbabaei,
Volume 12, Issue 3 (9-2022)
Abstract

Introduction: Studies show that in many cases, environmental hazardous agents such as heat, noise, as well as chemical pollutants cause adverse health effects through the mechanism of oxidative stress. This study has examined the effect of exposure to noise and whole-body vibration (WBV) on some parameters of oxidative stress (enzyme superoxide dismutase (SOD), total antioxidant capacity (TAC), and malondialdehyde (MDA)) of workers in a foundry industry.
Material and Methods: The workers were selected based on the calculations related to the sample size and taking into account the inclusion criteria as well as completing the informed consent form. The level of exposure to noise and WBV was measured according to ISO 9612 and ISO 2631, respectively. For each worker, the time-weighted average was calculated. The level of exposure of workers to the studied stressors was divided into three categories: low, medium, and high. The blood samples were taken from all participants between 7-9 am. Then, via ELISA method according to the protocol of the kit manufacturer, the samples were prepared and analyzed. Univariate analysis of variance was performed to determine the “effect size” of each physical stressors on the studied parameters.
Results: The mean levels of MDA, SOD, and TAC among participants were 22.48 (11.19) nmol / ml, 61.28 (10.97) U / ml, and 1.64 (0.90) mM, respectively. Among the exposure variables, noise had the largest effect on MDA level (B = 0.090), which was not statistically significant (P = 0.865). WBV had the largest effect on SOD level (B = -1.469) which was statistically significant (P = 0.016). None of the studied variables had a significant effect on the TAC level; however, among the exposure variables, the greatest effect was related to WBV (B = -0.077; P = 0.133).
Conclusion: The effect of noise on oxidative stress parameters was not statistically significant. The effect of whole-body vibration on oxidative stress parameters except SOD was not statistically significant. Noise and WBV had increasing effect on MDA and decreasing one on SOD and TAC levels.

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