Background and Aim: Cerebral palsy is characterized by non-progressive abnormalities in the developing brain that creates a cascade of motor deficits and finally affects functional activities. Limited hand function is a characteristic of the movement disorders in children with cerebral palsy which leads to disability in performing activities of daily living, work and play. The purpose of this study was to investigate the effects of wrist Kinesio Taping on hand function of children with spastic diplegic cerebral palsy.

 Materials and Methods : In this randomized clinical trial and single-blind study, 26 children (3-6 years old) with spastic diplegic cerebral palsy were selected by convenient and simple sampling and randomly divided into two intervention and control groups. During the study for 12 days ,control group received only common occupational therapy treatment or Neuro-Developmental Treatment (NDT). Intervention group received both NDT and wrist Kinesio Taping for 24 hours a day on both wrists. Assessment tool was QUEST for evaluating quality of upper extremity skills and Modified Ashworth Scale for assessing spasticity of wrist before and after intervention in both groups. Data were analyzed by independent t-test and Wilcoxon rank sum.

 Results : The results showed significance increase of total QUEST score (P=0.029) and significance difference in domains of dissociated movements (P=0.003) and grasp (P=0.008) in Kinesio Taping group. However, there were no significant differences in weight bearing (P=0.46) and protective extension (P=0.89) domains. The data showed that wrist Kinesio Taping was effective in reducing spasticity of right wrist(P=0.004) but no significant difference for left wrist(P=0.06).

 Conclusion: Wrist Kinesio Taping technique revealed to be effective in increasing quality of upper extremity skills of spastic diplegic cerebral palsy children in domains of dissociated movements and grasp. Moreover, it was concluded that this technique can be effective in reducing spasticity of right hand due to more active use of dominant hand.