Showing 7 results for Ansari
M Naghipour, F Azadeh, H Dargahi, Sj Ghazi Mir Saedi, M Hasanzadeh, J Khansari,
Volume 2, Issue 3 (20 2008)
Abstract
Background and Aim : Creation of knowledge management (KM) and efforts to use it in the university research programs shows the university society activity to enhance intellectual qualities and improve this effectiveness of the universities on the development and advancement in the countries. The objective of present study was to evaluate the status of organizational culture and structure for implantation of KM in the central libraries of the medical science universities in Iran.
Materials and Methods:The present work is an applied research and descriptive-analytic study. The survey population consisted of 80 people who were directors or managers of 29 central libraries in medical science universities. Data collection method was used based on the questionnaire. The validity was checked by researchers and reliability Cronbach's alpha (>0.7). The data & information were analyzed with descriptive statistics and independent t-test by SPSS software package ver. 15.
Results: The findings showed that the status of "organizational structure" of KM in these libraries was intermediate, whereas "organizational culture" was in the suitable status. Also in the libraries in which decentralization, revision in knowledge sharing process and Internal Network for knowledge sharing is adopted, higher organizational culture as compared with other libraries, and have significant differences in them (p<0.05).
Conclusions: The result of present work is a proof for willingness and propensity of the Iranian librarians and their managers in the process of knowledge sharing and utilization of KM is at the proper level. Therefore, the authorities should provide the necessary structures and other complementary backgrounds for the utilization of KM in Iranian university libraries.
Sj Ghazimirsaied, M Hemmat, H Dargahi, J Khansari,
Volume 4, Issue 3 (20 2011)
Abstract
Background and Aim: Using Hirsch index as an important tool to describe the scientific outputs of researchers has caused some authors to increase their self-imposed parameters, increase, citing themselves. Therefore it is necessary to consider the effect of self-citation on Hirsch index for every author to have better measuring on the quality of researchers scientific production.
Materials and Methods: This research is descriptive method of citation analysis in general and specifically self-citation analysis. The study, are Iranian prolific authors in the field of medicine that have at least 30 documents indexed in Web of Science database between 2004 to 2006. Citations following up was studied till December 2010 Results was analysis using Excel software version 2007.
Results: The average self-citation observed between prolific authors in medical field was 25/89 percent. Hirsch index for 30/77 percent of authors had changed considerably. The authors rating scheme based on Hirsch index was done after removing self - citation so that 38/46 percent of authors decreased to lower level.
Conclusion: Considering that 10 to 30 percent of self-citation can be normal and justified, the status of self-citatin of Iranian prolific authors in medical field is desirable. Also, lower rates of self - citation of these authors doesnot affect Hirsch index.
Abolfazl Kalantari , Farhad Zaker, Shahla Ansari Damavandi , Heydar Sharafi , Seyed Amir Yazdanparast ,
Volume 8, Issue 5 (1-2015)
Abstract
Background and Aim: Acute lymphoblastic leukemia patients show differences in serum levels and toxicity associated with methotrexate after its treatment. Pharmacogenetics is an important determining factor for these differences. In this study, the effect of +452 C / T and -401C / T polymorphisms of GGH gene on serum levels and toxicity associated with methotrexate was studied. The aim of this study was to evaluate the effect of +452C / T and -401C / T polymorphisms of GGH gene on methotrexate level in serum and its associated toxicity in patients with acute lymphoblastic leukemia. Furthermore, the frequency of the above polymorphisms was investigated for the first time in Iran.
Materials and Methods: The prevalence of these polymorphisms was assessed in 83 Iranian patients with ALL using PCR and RFLP. The relationship between the polymorphism and serum methotrexate levels and its toxicity was estimated by calculating the Odds Ratio.
Results: No correlation was found between +452CT polymorphism and serum levels of methotrexate and methotrexate-related toxicity. -401CT polymorphism was found to be correlated with methotrexate-related toxicity leading to thrombocytopenia (95% CI= 0.009-0.019, odds ratio=0.265) and leukopenia (95% CI = 0.021-0.042, odds ratio = 2.182) in consolidation phase of the treatment.
Conclusion: Evaluation of patients for methotrexate-related polymorphism of GGH gene may be useful in selecting the appropriate dose of methotrexate and reducing the toxic side effects associated with its administration.
Aziz Rezapour, Farbod Ebadifard Azar, Negar Yusef Zadeh, Fatemeh Hasanpour, Hossein Bagheri Faradonbeh, Saeideh Ansari Nosrati, Zahra Asemaneh , Mohammad Hossein Ghafoori,
Volume 9, Issue 2 (7-2015)
Abstract
Background and Aim: Receiving and using health care services is called
health services uitilization. There are many socio-economic factors including
income, culture, age and education affecting the utilization of the services. This
survey aimed to study socio-economic determinants of health utilization in Tehran.
Materials and Methods: This was a cross-sectional, population based health
survey done in year 2013. The sample was 792 households living in Tehran. Data
was collected by WHO (households) questionnaire, and analyzed using logistic
model and stata12.
Results: Among the study variables, households' income, presence of a person
with chronic disease, education of the head of the household, and presence of
person older than 60 and younger than 14 in households, had a significant
statistical relationship with utilization. Insurance coverage had a vague and weak
effect on the utilization of health services. Moreover about 23 percent of the
households were not under insurance coverage.
Conclusion: According to the announced policies by the supreme leader of the
Islamic Republic of Iran to the Ministry of Health and Medical Education and by
cconsidering the main focus of these policies on the universal insurance coverage,
households financial security and reform of the payment system identifying
households that utilize more health care services than any others because of any
socio-economic reasons is a considerable step for providing financial security for
vulnerable households and reforming health care system at the national level.
Fereshteh Farzianpour, Saeadeh Ansari Nosrati, Abbas Rahimi Foroushani ,
Volume 10, Issue 5 (1-2017)
Abstract
Background and Aim: Due to social development, population growth, industrialization of countries and require some work, most of the employees are working with program shift. The purpose of this study was determination of relationship between nurses shift rotation and personality characteristics and coping strategies in selected private hospitals in Tehran, Iran.
Materials and Methods: In this descriptive and cross-sectional study standard shift work questionnaire and Eysenck personality questionnaire was used. After confirming the validity and reliability (Cronbach's alpha 0.73), the questionnaire was distributed among 305 nurses and 6 non-governmental hospitals in Tehran on the cluster random sampling method. Descriptive and analytical methods were used for data analysis using SPSSv.22 software.
Results: 43.6 percent of nurses participating in the study were introverted and 56.4 percent were extroverted. The results showed that there was a meaningful statistical relationship between age and health (p=0.008), gender and physical health (p=0.015), education level and physical health (p=0.014), gender and physical-cognitive anxiety (p=0.006), age and family- socioeconomic status (p=0.001), marital status and family-socioeconomic status (p=0.001), second occupation and family-socioeconomic status (p=0.001).
Conclusion: Planning according to nurses working hours standard and to avoid overtime, especially nurses who have more experience can prevent severe complications of shift work and improve health and the quality of care.
Mohammad Mehdi Soltan Dallal, Abolfazl Keshavarz, Ebrahim Kord, Nastaran Ansari, Zamaneh Hajikhezri, Katayoun Samimi-Rad,
Volume 12, Issue 1 (5-2018)
Abstract
Background and Aim: At the present time one of the strategies in vaccine design is generation of fusion proteins containing (including) immunogen of infectious agents and adjuvants. In this study design and construction of E2-fliC fragment as a vaccine candid was conducted by using fliC gene from Salmonella enterica and E2 gene from hepatitis C virus.
Materials and Methods: To prepare the E2-fliC construct, E2 and fliC fragments were first amplified from pBluscript-E2 and pBluscript-fliC, respectively by PCR method. To generate pcDNA-E2-fliC plasmid, E2 was subcloned into plasmid pcDNA3.1 (+) which was extracted from DH5α cells. The fliC sequence was then cloned into the pcDNA3.1-E2. To evaluate the expression of E2-fliC construct, it was inserted into the pEGFP-N3 expression vector. Then COS-7 cells were transfected with pEGFPN3- E2-fliC to evaluate the expression of the fusion protein by observation of the EGFP signal under the fluorescence microscope.
Results: By development of GFP fluorescent using fluorescence microscopy the most expression of E2-fliC construct was observed at 24h after transfection. The accuracy of the recombinant plasmid pcDNA-E2-fliC was confirmed by PCR, restriction enzymes and DNA sequencing.
Conclusion: Our findings suggest that E2-FliC fusion protein has expressed efficiently and most likely similar to HCV E2 protein induces immune system of mice after their immunization with pcDNA-E2-fliC.
Nazli Ebrahim Netaj, Maryam Rezaei Dastjerdi, Saham Ansari, Kamran Amirian Chayjan, Mahdi Sepidarkish, Jalal Jafarzadeh, Akbar Hossein Nejad, Mojtaba Taghizadeh Armaki,
Volume 16, Issue 4 (Oct 2022)
Abstract
Background and Aim: Denture stomatitis is the most prevalent oral mucosal lesion among denture wearers. Because there have been multiple reports of resistance of Candida species to antifungal drugs in the last two decades, if the antifungal properties of Achillea millefolium and Trachyspermum ammi are validated, these compounds may be a suitable adjuvant drug along with the use of common antifungal drugs. Therefore, the current study aimed to assess the antifungal activity of alcoholic extracts of Achillea millefolium and Trachyspermum ammi against Candida albicans isolated from denture stomatitis.
Materials and Methods: Antifungal sensitivity of 50 isolates of C. albicans with the origin of denture stomatitis to the alcoholic extracts of Achillea millefolium and Trachyspermum ammi plants as well as the antifungal drugs miconazole and nystatin was determined by broth microdilution method and according to CLSI-M27S4 guidelines. The range of dilution for all compounds was 0.016-16 μg/ml. A concentration of compounds that showed at least 50% growth inhibition as compared to the positive control group was considered MIC (minimum growth inhibitory concentration). Statistical analysis was done using SPSS software and the significance level was considered as P<0.05.
Results: The MIC ranges in microbroth dilution method for the antifungal drugs miconazole, nystatin, as well as the alcoholic extracts of Achillea millefolium and Trachyspermum ammi plants on C. albicans, were close to each other, indicating that their effectiveness against C. albicans species does not differ significantly (P<0.05). The Achillea millefolium methanolic extract had the highest and lowest MIC values, with an average of 2.67±2.55 μg/ml and 0.067±0.057 μg/ml, respectively. A significant difference (P<0.001) was observed when the MICs outcomes the herbal alcoholic extracts and antifungal drugs were compared.
Conclusion: Based on the obtained MICs, Achillea millefolium and Trachyspermum ammi alcoholic plant extracts have a lesser efficacy than the antifungal drugs, but even though they may have a lower MIC and more effectiveness than other chemical drugs.
