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Identification And Ranking The Components Serving Doctors And Paramedics Manpower In Choosing Their Place Of Employment And Durability
Hosein Sanjari , Zeinab Moghadamifard, Behnosh Heydarzadeh, Hosein Mobaraki,
Volume 8, Issue 6 (3-2015)
Abstract

Background and Aim: In order to harmonize the demands of doctors and paramedics serving subject to the law Ministry of Health with intended policy of the health ministry on determining priorities and equitable distribution of mentioned resources, the first step that should be taken is to organize resources and to consider their viewpoints . The goal of this paper was to Identify and rank the indexes related to paramedics and ranking them on choosing their place of employment and their durability.

Materials and Methods: The research was a descriptive- Analytic study . Participants in the study were resources of law service of doctors and paramedics in 2012 . All data were analyzed by statistical software SPSS and EXCEL . Friedman test was used for prioritizing and determining the importance of each of the factors influencing the selecting places of employment . 

Results: Among all the factors , social / beliefs factors with mean value of (SD ) 3/52 (0/019) had the greatest influence on the choice of place of service of subject to the law, and it is the first priority of service location by field of study , educational level , place of service and the service index subjects served . 

Conclusion: In order to properly organize and direct the Ministry of Health , the most effective factor is correct understanding of the priorities , needs and mental ideal needs of the mentioned resources . Especially the changes in behavior patterns and easy access to information in large extend will create huge changes of current generation than previous generations.


Relationship between FSH Receptor’s Exon 10 Polymorphisms with IVF Results in Iranian Women
Maliheh Javadi-Arjmand, Elia Damavandi, Hamid Choobineh, Majid Kabuli, Mohsen Ghadami,
Volume 18, Issue 3 (5-2024)
Abstract
Background and Aim: Follicle stimulating glycoprotein hormone (FSH) exerts its functions through its receptor (FSHR). In women of reproductive age, this hormone causes the growth and development of follicles in the ovary during the follicular phase of the menstrual cycle. This hormone is widely used in the treatment of infertility. Several polymorphisms have been reported so far in the FSHR gene, which are effective in the ovarian response, but the FSHR gene has two very common single nucleotide polymorphisms at positions 680 and 307 in exon 10. One of them at position 307 changes the amino acid threonine to alanine and the other at position 680 changes asparagine to serine. The polymorphism at position 307 of exon 10 is in the extracellular region of the receptor and the binding site of the hormone, which can be affected in response to internal and external FSH stimulation. These two SNPs have been reported to be associated with various ovarian responses and IVF outcomes in different populations. Different studies have particularly focused on rs6166 (p. Asn680Ser), but this study was conducted to investigate the possible association between rs6166 and rs6165 (p. Thr307Ala) and the IVF outcome.
Materials and Methods: After blood sampling and DNA extraction, the two polymorphisms in exon 10 of FSHR gene were analyzed using PCR-RFLP method in 120 women randomly assigned to two equal groups including IVF successful and IVF unsuccessful infertile women. The selection of patients to enter the study as well as the criteria for successful IVF are described in the text. In order to confirm the results, DNA sequencing was done for some selected samples. Finally, the results were analyzed using SPSS software.
Results: No significant differences were found in either SNPs between successful IVF and unsuccessful IVF patients in allelic frequencies (P-value>0.05).
Conclusion: Despite the different results of the studies conducted regarding the effect of FSHR gene polymorphisms (rs6165 and rs6166) in different populations, considering the lack of significant difference in the frequency of the above polymorphisms in the studied population, it is concluded that these two polymorphisms cannot be used to predict the outcome of IVF in Iranian infertile women.

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