Showing 11 results for Ghasemi
H Dargahi, M Ghazi Saidi, M Ghasemi,
Volume 1, Issue 2 (20 2008)
Abstract
Background and Aim: Ever-increasing development of access to appropriate software and hardware for e-learning especially development of worldwide web has suggested new horizons for educational institutes. It is much important in medical sciences, because Medical Sciences deal with the health of human beings. Since beside issues related to education, research and information production, appropriate treatment of the patients is possible through having up to date and new information as well. For this reason Medical Sciences utilize information technology as soon as possible in order to prepare essential information for physicians quickly. This article discusses the role of e-learning in Medical Sciences universities.
Materials and Methods: in this literature review article, gathering information has been done by using paper and paperless documents related to the topic.
Results: For implementing of e-learning in Medical Sciences organization there should be some infra-structures, standards and skills which are to be noted prior to commencing e-learning. These infra-structures, standards and skills play a special role in successful implementation of e-learning.
Conclusion: Regarding the advantages of e-learning naturally possesses, there is no doubt in necessity of developing Medical Sciences e-learning. But the ways of efficient access to this sort of education is much more important. So, it is recommended that by comparing the existing process in the world and using the experiences of prominent countries in this field, the most appropriate method be chosen and applied.
H Dargahi, M Ghazi Saidi, M Ghasemi,
Volume 3, Issue 3 (25 2010)
Abstract
Background and Aim: Electronic learning system is a new educational process which designed upon basis of computerized technology, multimedia and processors. It has several potentials and contexts.
To do comparative study and utilizing of successful electronic learning in developed countries could help us to develop this new process in Iran's Universities of Medical Sciences.
Materials and Methods: This research is developed descriptive comparative study in 2007 - 2008 by using of developed countries universities websites information and 62 references and keywords such as Electronic Educations,Medical Sciences Courses,Commutation Technology, Comparative Study and University in the field of electronic medical sciences. Then, the findings will compare with each developed countries universities and Iran's Universities of Medical Sciences.
Results: The results showed that Manchester and Dekin University have much experience in developing of electronic learning. The Students should be assessed by attendance, online and blended in developed universities.
Degree based courses are only present in South - Africa University, meanwhile single courses and training are present in other universities. Electronic health sciences courses and training are developed much more in compressive with others.
Discussion and Conclusion: The studied universities are different in history of construction, student assessment type, homework presence type, registration procedures, electronic medical education type with each other.
Iran's Universities of Medical Sciences, electronic education have several deficiencies in comparison with developed countries universities. We suggest appropriate technological and cultural infrastructure and use's skill improvement to develop this process in our country's universities of Medical sciences.
R Ghasemi Barghi, Ghr Hassanzadeh Ghulam, M Javadi, M Asadi, B Bayat, N Saiepour, H Choobineh,
Volume 5, Issue 2 (20 2011)
Abstract
Background and Aim: The disabled people are a part of our society (1%) and a disabled will face incorrect behaviors from childhood that is caused by an incomplete understanding of the society, but family can play a constructive role to increase the disabled abilities.
This study was conducted to determine the views of deaf, blind and physical motor handicaps and their families regarding disability in the family in the Qazvin and Karaj.
Materials and Methods: One hundered and fifty handicaps and their families from handicaps center, welfare office, the disabled school students, the Mostazafan and Janbazan foundation were enrolled in this study. Information was collected by using 2 questionnaires. T test and Analyses Of Variance have been applied for data analysis, using SPSS software.
Results: The results show that among different disabilities, the deaf ones and their families had more positive view than other disabled ones about their disabilities.
Also, increasing the number of family members can cause more negative view about disability (p<0.05). This study shows that there isn't a significant relationship between the disabled view and his / her gender, cause of disability and parents high education
Conclusion: With regard to the similarity of the disables and their families views about disability and also their need to obtain more awareness about disability, the disable's needs and complications, it is necessary to stress on correct training of disabled person, his/ her family and the society.
Mahdihe Ghasemi, Fatemeh Nadali, Seyed Naser Ostad, Farhad Zaker, Shahrbanoo Rostamy, Hossein Dargahi,
Volume 6, Issue 4 (15 2012)
Abstract
Background and Aim: Chronic myelogenous leukemia is characterized by Philadelphia (Ph) chromosome, the presence of BCR-ABL fusion gene and constitutive activation of the ABL1 tyrosine kinase. Despite an excellent result of target therapy by imatinib, some patients develop resistance to imatinib. In this study Efficacy of HESA-A on proliferation and apoptosis of K562 cell line was assessed.
Materials and Methods: In this study doubling time of K562 cell line was calculated. The cells were affected by various concentrations of HESA-A(1,2,4 and 8 mg/ml respectively). Cytotoxicity and IC50 dose of HESA-A were detected by MTT and trypan blue exclusion assay. Apoptosis was assessed by flowcytometry after 48 h cell treatment in the presence of IC50 dose.
Results: Doubling time of K562 cells was 24 hours. HESA-A reduced the number of viable K562 cells in a concentration dependent manner.IC50 dose was 3.5 mg/ml. In flowcytometry analysis of apoptosis, 19.22% of the treated cells were located in the position of the necrotic cells.
Conclusion: The results of MTT and trypan blue exclusion assay suggest that HESA-A inhibits the growth of k562 cells in a concentration dependent manner and induces necrosis in K562 cells.
Zahra Ghasemi Aghbolaghi, Fereydoon Azadeh, Fatemeh Sheikhshoaei,
Volume 12, Issue 2 (Jun & Jul 2018)
Abstract
Background and Aim: In the field of scientometrics, little attention has been paid to stem cells. Therefore, the purpose of this study is to draw a Scientific Map of stem cells area (co-word analysis) based on the papers indexed in Web of Science database in selected countries during the years 2011-2013.
Materials and Methods: This study is based on descriptive method, and it was conducted by scientometrics and co-word analysis technique. In this study, 34,142 articles were analyzed from Web of Science database. The search system of Web of Science is a tool for collecting data. Data analysis was done using Web of Science analysis system and CiteSpace software.
Results: Most productions in stem cells are in English and belong to America. Stem cell, cell differentiation, in vitro, gene expression, mesenchymal stem cells, embryonic stem cells and transplantation are the most frequently used words and hot topics in this field.
Conclusion: The growing trend in this area has caused different subject fields to enter stem cells areas. Considering the high frequency of embryonic stem cells in the field, it can be said that different diseases such as spinal cord problems and heart diseases can be treated using these cells.
Parichehr Hanachi, Zahra Ghaseminya, Khosro Sadeghniyat, Abolfazl Golestani,
Volume 12, Issue 3 (Aug & Sep 2018)
Abstract
Background and Aim: Obstructive sleep apnea (OSA) is one of the most common sleep disorders that, despite the high prevalence, most people are unaware of it. The reason for this disorder is obstruction of the respiratory tract, which reduces blood oxygen as a result of frequent waking during the night. In this study, the status of antioxidant defense was considered as one of the most important mechanisms involved in preventing the consequences of this complication.
Materials and Methods: The 35 subjects of OSA were selected and categorized according to the apnea-hypopnea index (AHI) in two groups: Mild OSA (n=17) and severe OSA (n=18). The fasting blood samples were taken in order to evaluate the antioxidant defense status of the glutathione peroxidase activity (GPx) and glutathione (GSH) content.
Results: The results showed the mean values for GPx in patients with mild and severe apnea were 36.6±2.2 and 35.3±3.7 (u/gHb), respectively. Also, the mean values for GSH content in patients with mild and severe apnea were 0.54±0.1 and 0.68±0.1 µM, respectively that showed a 23% increase (P˂0.05) in severe apnea patients.
Conclusion: There was no significant difference in the GPx activity of mild apnea, however, patients with severe apnea showed a significant increase in GSH levels compared to mild apnea (P<0.05), which may indicate a long-term response to oxidative stress alters gene expression and increases the level of these biomarkers in a long time.
Fatemeh Bahrami-Banan, Mohammad Hasan Sheikhha, Nasrin Ghasemi, Mohammad Majdizadeh, Bibi Fatemeh Haghiralsadat,
Volume 12, Issue 4 (Oct & Nov 2018)
Abstract
Backgrounds and Aim: One of the effective strategies for targeting chemotherapy in the treatment of cancer is the use of lipid nano-carriers. In this study, an optimal formulation of niosomal drug containing doxorubicin has been developed to better fight cancer cells.
Material and Methods: Niosomal vesicles were prepared using phosphatidylcholine (22%), span60 (52/5%), cholesterol (22/5%) and DSPE-PEG2000 (5%) by thin-film method. Doxorubicin were loaded into the niosomes using inactive loading method. Their physico-chemical features were assayed using Zeta-Sizer, FTIR and SEM, and drug release amount was calculated at 37° C and 44° C. At the end, the toxicity of the nano drug carrier system was measured on the KG-1 cell line of the bone marrow cancer by MTT method.
Results: Niosomal vesicles containing Doxorubicin showed the size of 160.37±65.2 nm, 94.18% drug encapsulation efficiency -58.11± 1.24 mV of zeta potential and polydispersity index (PDI) of 0.234±0.02 The prepared niosomal system presented drug controlled release and FTIR investigation showed almost no interaction between nano-carrier containing drug and the drug itself. As well, morphological examination of nano-carriers using SEM microscopy revealed that they have spherical structures. Also, cellular studies showed that drug toxicity was higher in encapsulated conditions compared to non-encapsulated conditions.
Conclusion:The results of this study, meanwhile confirming the proper physicochemical characteristics of the system and being Slow-release system indicate that this nano-carrier anionic increases the toxicity of the drug for the KG-1 cell line of the bone marrow, thus, this niosomal nano-carrier can be a suitable carrier for drug delivery to cancer cells.
Mohammad Reza Haji Ghasemi, Mehdieh Azhdari,
Volume 14, Issue 2 (Jun & Jul 2020)
Abstract
Background and Aim: Neurological disorders occur under the conditions when there is perturbation in one part of the brain or the nervous system. The increasing outbreak of neurological disorders and its high expenses imposed on society have made the necessity to modify the policies of health care. This study calculated the cost of services for pediatric neurology patients to reduce costs.
Materials and Methods: This quantitative cross-sectional descriptive-analytic case study implemented a Fuzzy Time-Driven Activity-Based Costing(FTDABC) model in treating pediatric neurology patients in 2016. The Wilcoxon nonparametric test was used to test the hypothesis of the research and investigate the significant difference in the cost of services provided to patients in the FTDABC and the traditional costing model.
Results: The results confirmed a meaningful patient services costs in both methods; the cost of patient care using FTDABC model was estimated to be 5,736,843,432 Rials, 41.61% of which goes to overhead and 5.94% goes to idle capacity. Visiting and counseling activities, controlling vital signs, and patient displacement were identified as the most time-consuming activities in the treatment process, respectively.
Conclusion: According to the research findings, it seems necessary to reform human resource management and reduce idle capacity to increase the effectiveness of hospital resources and improve the therapeutic processes. If management can reduce patient displacement activity by 20%, it will result in 2.89% reduction of time and 1.86% of the cost of the treatment process.
Hamzeh Amin-Tahmasbi, Maede Ghasemi,
Volume 14, Issue 4 (Oct & Nov 2020)
Abstract
Background and Aim: The growing healthcare expenses, technological advancements and increasing competition in healthcare services, brings up new challenges for healthcare industry in providing appropriate services to customers. The Lean methodology, which is a managerial approach, provides tools necessary to eliminate waste and increase customer satisfaction through increasing quality of the services and decreasing the wait times and costs. The Scope of this paper is to determine and rank the lean criteria for hospitals.
Materials and Methods: 22 base criteria for a lean organization was selected and reconciled to hospitals from literature review. Then they were evaluated by experts in the field using Likert scale, leading to 18 criteria. The correlation of these criteria was found using ISM methodology, followed by ranking of these criteria. Lastly, the criteria were categorized utilizing MICMAC analysis.
Results: utilizing MICMAC analysis, the "defining the flow of processes & continuous improvement", "utilizing visual surveillance to understand the situation & exploit the problems" were identified as the most important variables.
Conclusion: In order to increase quality of services and customer satisfaction and to reduce operating costs, hospitals are advised to utilize lean methodology. In which case the management should pay more attention to the two more important criteria derived by MICMAC analysis, "Defining the processes in order to find problems" and "Continuous improvement and utilizing visual surveillance in order to find problems".
Seyede Mahrokh Alinaghi-Maddah, Maryam Zahedi Tabarestani, Kazem Kazemnejad-Tabrizi, Samira Ghasemi, Fatemeh Mehravar,
Volume 16, Issue 2 (Jun 2022)
Abstract
Background and Aim: Atracurium, as one of the neuromuscular relaxants, is one of the most important irritants of the allergic reaction during anesthesia, which causes the release of histamine. This study was conducted with the aim of determining the effect of hydrocortisone on hemodynamic changes resulting from atracurium drug in patients with upper limb fractures under general anesthesia.
Materials and Methods: In this double-blind randomized clinical trial study, 50 patients with upper limb fractures under general anesthesia, 18 to 60 years old with ASA class 1 and 2, were randomly assigned to two groups of hydrocortisone and placebo (distilled water). In intervention group, 30 minutes before entering the operating room, vial oxycort (hydrocortisone) was administered intravenously and bolus with 300 ml of normal saline. Hemodynamic changes in patients before administration of hydrocortisone, 30 minute after administration, 5 minutes after the peak effect of atracurium (before intubation) and after extubation were recorded in the relevant checklist and comparisons were made between the two groups.
Results: There was no significant difference between the two groups in terms of age, gender and duration of surgery. Systolic blood pressure 5 minutes after the peak effect of atracurium (before intubation) in the control group was lower than the intervention group and this difference was statistically significant (P=0.02). Thirteen minute after hydrocortisone administration, mean blood pressure systolic and diastolic patients decreased and this decrease continued after administration of histamine release atracurium (before intubation); but after extubation, the patients’ mean blood pressure has increased. Also, after administration of atracurium, the mean heart rate of patients decreased by 14.44 units as compared to before administration of hydrocortisone and this decrease was significant (P=0.001).
Conclusion: The results of this study show that hydrocortisone can be used as an effective factor in maintaining hemodynamic stability in patients under general anesthesia. However, its use as a factor in maintaining hemodynamics has not yet been widespread and needs further investigation.
Parisa Moradimajd, Shahnam Sedighmaroufi, Shaqayeq Taghizadeh, Mr Jamileh Abolghasemi, Alireza Babajani,
Volume 18, Issue 1 (3-2024)
Abstract
Background and Aim: One of the basic principles in the safety of drug therapy for patients is the correct registration and labeling of anesthetic drugs, which can lead to the reduction of drug errors, the increase of drug and patient safety, the reduction of drug consumption and the environment, and the optimization of hospital costs.
Materials and Methods: This descriptive-analytical and cross-sectional research was conducted in February 2022 in the operating rooms of Iran University of Medical Sciences hospitals. The participants included 177 Anesthesia experts working in the hospitals’ operating rooms, who were included in the study by census method. The data was collected using the checklist for evaluating anesthetic drug registration and labeling guidelines and analyzed using SPSS software and one-way ANOVA, Fisher, and Pearson correlation coefficient statistical tests. The significance level was considered P value < 0.05.
Results: The average compliance with the guidelines for registration and labeling of anesthetic drugs in all hospitals was 3.559 out of the total score of 16. The average adherence to guidelines in 8 hospitals was significantly different from each other (P < 0.001). Hazrat Ali Asghar Hospital had the highest compliance rate, averaging 10.333 out of 16. Firouzgar and Shahid Akbarabadi hospitals were in the next rank, averaging 10.11 and 6.65, respectively. There was a negative and significant correlation between the level of compliance with the guidelines and the average work experience and age of the experts (P=0/17); However, gender did not significantly correlate with the degree of adherence to the guidelines(P=0/596).
Conclusion: According to the obtained results, compliance with the guidelines for registration and labeling of anesthetic drugs in most hospitals was assessed as weak and at an unfavorable level. Considering the importance of this issue in reducing medication errors and increasing patient safety, it is necessary to use empowerment and retraining courses for Anesthesia experts according to the latest guidelines.
