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H Dargahi , M Ghazi Saeedi , R Safdari , M Hamedan ,
Volume 4, Issue 2 (19 2010)
Abstract

Background and Aim: The benefits of a unique computerized medical records and communication equipments is utilized to collect, storage, process, extract and relate to patient care information and management information. If this utilization is in accordance with the needs of managers and staff of medical records, many of the nation's health system problems will be dissolved. Information systems in health supply system by compiling, analyzing and publishing data provide utilization of information improve the health of the society. The purpose of this study is to investigate the process of clinical information systems in general hospitals of Tehran University of Medical Sciences based on available clinical information system in these hospitals.

Materials and Methods: This descriptive study is an application study that conducted in order to determine the process of clinical information system in general hospitals of Tehran University of Medical Sciences based on available clinical information in these hospitals. The required data have been collected by a valid and reliable questionnaire. Descriptive statistics were used to analyze data.

Results: With regard to the current condition and the importance of survey of the process of clinical information system in the studied hospitals, the authors provided the desired checklist in general hospitals with studying the related system in America, Australia and England countries, on the basis of country requirements in the form of clinical information system processes. We studied clinical information system processes in departments of admission, filling and retrieving, statistical and coding and also soft wares in this department.

Discussion and Conclusion: It is necessary to create a coordinated and integrated clinical information system with suitable process and empower experts in the field of proper use of data with regard to the position of information system in each organization and its fundamental role in the adoption of accurate policies. We found that relative frequency of clinical information system processes is more than 60% in this department and clinical information system elements was observed 75% in all the departments except admission.


Keivan Keramati, Sina Adib, Mahmood Ahmadi Hamedani, Leila Mohammadnejad Nasrabadi,
Volume 19, Issue 2 (7-2025)
Abstract

Background and Aim: BronchoT.D is an Iranian herbal drug manufactured for human consumption and has anti-cough and expectorant properties. Isoproterenol is a non selective agonist of beta-adrenergic receptors that although has been used as a drug in cases such as bradycardia, but based on the results of some studies, it has been determined that isoproterenol can also lead to tissue damage and hematological changes. The aim of this research was hematological evaluation of the interaction of BronchoT.D® with isoproterenol.
Materials and Methods: This was an experimental study. Eighteen male wistar rat were used in 3 experimental groups (each group 6 rats) including control, recipient of isoproterenol and normal saline and recipient of isoproterenol and BronchoT.D. There was no intervention in the control group. Isoproterenol was administered via twice injection and normal saline and BronchoT.D were administered five times orally. Finally, blood was collected from the rats and White Blood Cells (WBC), Red Blood Cells (RBC), Hematocrit (Hct), Hemoglobin (Hgb), Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin Concentration (MCHC) and Platelets (Plt) were measured. Statistical analysis of data was performed through one-way analysis of variance using SPSS software. 
Results: In terms of WBC, the difference between the experimental groups was not significant. The isoproterenol and normal saline receiving group had a significant increase in terms of RBC, Hct, Hgb and Plt as compared to the control group. The difference between the isoproterenol and BronchoT.D receiving group was not significant in terms of RBC, Hct and Plt as compared to the control group. In terms of Hgb and MCHC, the isoproterenol and BronchoT.D receiving group had a significant increase as compared to the control group. In term of MCV, the difference between experimental groups was not significant. The isoproterenol and normal saline receiving group did not differ significantly in comparison with the control group in term of MCHC. 
Conclusion: Based on the findings of this study, it can be concluded that BronchoT.D not only prevents some hematological changes caused by isoproterenol, such as an increasing of RBC and plt, but can also increase the oxygen-carrying capacity of blood through a significant increase in Hgb and MCHC. BronchoT.D probably causes such effects by counteracting oxidative stress or by directly affecting the bone marrow, although additional researches are necessary to investigate such probablities.


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