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Showing 2 results for Hooshmand Moghadam

Javad Norouzi, Afsaneh Khosravi, Babak Hooshmand Moghadam, Abbas Ali Gaeini,
Volume 15, Issue 1 (Apr & May 2021)
Abstract

Background and Aim: Excessive production of free radicals and the accumulation of oxidative damages play an important role in accelerating the aging process. However, one of the ways to fight against aging and related diseases is through physical activity. The aim of the present study was to investigate the effect of 12 weeks of resistance training on oxidative stress indicators (8-iso-prostaglandin-F2α: 8-iso PGF2α) and oxidative DNA damage (8-hydroxydeoxyguanosine: 8-OHdG) in elderly men.
Materials and Methods: In this quasi-experimental study, 30 elderly men were selected voluntarily and purposefully as a statistical sample and were randomly divided into experimental (n=15) and control (n=15) groups. Participants of the experimental group performed resistance exercises three sessions per week for 12 weeks. At the beginning and end of the study, serum levels of 8-iso PGF2α and 8-OHdG were measured by ELISA method. Correlated and independent t-tests were used to compare intragroup and intergroup means, respectively.
Results: Serum values of 8-iso PGF2α (P=0.007) and 8-OHdG (P=0.013) decreased significantly after 12 weeks of resistance training. Also, there was a significant difference between the experimental and control groups in serum values of 8-iso PGF2α (P=0.009) and 8-OHdG (P=0.02).
Conclusion: It seems that 12 weeks of resistance training reduces the values of oxidative stress (8-iso PGF2α) and oxidative DNA damage (8-OHdG) indicators in older men. Therefore, regular resistance training can play an important role in preventing injuries caused by oxidative stress, especially in old age.

Bizhan Hooshmand Moghadam, Shadi Moazami Goudarzi, Amir Rashid Lamir,
Volume 18, Issue 1 (3-2024)
Abstract

Background and Aim: Adipokines imbalance causes pathological effects on this system. Exercise interventions can play an important role in regulating the secretion of adipokines. This study aimed to investigate the effect of 12 weeks of resistance training on the serum level of apelin, vaspin, and blood pressure in elderly men with hypertension.
Materials and Methods: In this quasi-experimental study, 24 elderly men with high blood pressure were selected purposefully and based on the inclusion criteria and were randomly assigned to resistance training (N=12) and control (N=12) groups. The participants of the resistance training group performed resistance training for 12 weeks and three days a week. At the beginning and end of the study, blood samples were collected to measure the serum level of apelin and vaspin. Data analysis was performed using SPSS version 24 software with dependent and independent t-tests at a significant level of less than 0.05.
Results: After 12 weeks of resistance training, there was a significant decrease in the serum level of apelin (P=0.002), vaspin (P=0.01), systolic blood pressure (P<0.001), and diastolic blood pressure (P<0.001) as compared to the pre-test. In addition, a significant difference was observed between the two experimental and control groups in the serum level of apelin (p=0.001), vaspin (P=0.001), systolic blood pressure (P<0.001), and diastolic blood pressure (P<0.001).
Conclusion: It seems 12 weeks of resistance training can improve systolic and diastolic blood pressure and regulate the secretion of adipokines apelin and vaspin in elderly men with high blood pressure.


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